DE69535643D1 - Process for the fermentative production of L-lysine and L-glutamic acid - Google Patents
Process for the fermentative production of L-lysine and L-glutamic acidInfo
- Publication number
- DE69535643D1 DE69535643D1 DE69535643T DE69535643T DE69535643D1 DE 69535643 D1 DE69535643 D1 DE 69535643D1 DE 69535643 T DE69535643 T DE 69535643T DE 69535643 T DE69535643 T DE 69535643T DE 69535643 D1 DE69535643 D1 DE 69535643D1
- Authority
- DE
- Germany
- Prior art keywords
- lysine
- glutamic acid
- fermentative production
- fermentative
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 title 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title 2
- 235000019766 L-Lysine Nutrition 0.000 title 1
- 239000004472 Lysine Substances 0.000 title 1
- 238000012262 fermentative production Methods 0.000 title 1
- 229960002989 glutamic acid Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/84—Brevibacterium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/843—Corynebacterium
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19546594 | 1994-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69535643D1 true DE69535643D1 (en) | 2007-12-27 |
Family
ID=16341537
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530306T Expired - Fee Related DE69530306T2 (en) | 1994-08-19 | 1995-08-09 | METHOD FOR PRODUCING L-LYSINE AND L-GLUTAMIC ACID BY FERMENTATION |
DE69535643T Expired - Lifetime DE69535643D1 (en) | 1994-08-19 | 1995-08-09 | Process for the fermentative production of L-lysine and L-glutamic acid |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530306T Expired - Fee Related DE69530306T2 (en) | 1994-08-19 | 1995-08-09 | METHOD FOR PRODUCING L-LYSINE AND L-GLUTAMIC ACID BY FERMENTATION |
Country Status (9)
Country | Link |
---|---|
US (1) | US5846790A (en) |
EP (2) | EP1293560B1 (en) |
JP (1) | JP2926991B2 (en) |
CN (1) | CN1079836C (en) |
BR (1) | BR9508730A (en) |
DE (2) | DE69530306T2 (en) |
ES (1) | ES2191710T3 (en) |
PE (1) | PE27597A1 (en) |
WO (1) | WO1996006180A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19681532T1 (en) * | 1995-08-23 | 1998-12-03 | Ajinomoto Kk | Process for the production of L-glutamic acid by fermentation |
JP3812019B2 (en) * | 1996-11-21 | 2006-08-23 | 味の素株式会社 | Process for producing L-glutamic acid by continuous fermentation |
US20030077765A1 (en) * | 1997-07-09 | 2003-04-24 | Ajinomoto Co. Inc. | Temperature-sensitive dtsR gene |
BR9810990A (en) * | 1997-07-09 | 2000-08-08 | Ajinomoto Kk | DNA-corineform bacteria, and processes to produce l-glutamic acid, and, to produce l-lysine and l-glutamic acid. |
CN101200742A (en) | 1998-03-06 | 2008-06-18 | 味之素株式会社 | Penicillin binding protein gene and process for producing l-glutamic acid |
AU756507B2 (en) | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
BR9906279A (en) * | 1998-12-18 | 2001-04-24 | Ajinomoto Kk | Chorineform bacteria, process to produce l-glutamic acid, and, dna. |
JP2003159092A (en) * | 1999-07-02 | 2003-06-03 | Ajinomoto Co Inc | Method for producing l-amino acid |
ES2272303T3 (en) * | 1999-07-23 | 2007-05-01 | Archer-Daniels-Midland Company | L-AMINO ACIDS PRODUCTION PROCEDURES THROUGH THE INCREMENT OF CELL NADPH. |
US6830903B1 (en) | 1999-07-23 | 2004-12-14 | Archer-Daniels-Midland Company | Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene |
CA2380320C (en) * | 1999-08-02 | 2015-01-06 | Archer-Daniels-Midland Company | Mutant bacterial strains l-lysine production |
US6984512B1 (en) * | 1999-08-02 | 2006-01-10 | Archer-Daniels-Midland Company | Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production |
JP2003506030A (en) * | 1999-08-02 | 2003-02-18 | アーカー−ダニエルズ−ミッドランド カンパニー | Metabolic engineering of amino acid production |
JP4427878B2 (en) * | 1999-08-20 | 2010-03-10 | 味の素株式会社 | Method for producing L-glutamic acid by fermentation method with precipitation |
US6927046B1 (en) | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
US6737262B1 (en) * | 2000-07-11 | 2004-05-18 | Robert I. Bolla | Animal feed containing polypeptides |
EP1789567A2 (en) * | 2004-09-01 | 2007-05-30 | Agrotechnology and Food Innovations B.V. | Enhanced substrate conversion efficiency of fermentation processes |
DE102005017508A1 (en) * | 2005-04-15 | 2006-10-19 | Basf Ag | Process for obtaining a basic amino acid from a fermentation broth II |
EP1930409B1 (en) * | 2005-08-26 | 2012-02-08 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for production of l-glutamic acid |
JP2010088301A (en) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | Method for production of l-amino acid |
BRPI0810011B1 (en) | 2007-04-17 | 2021-11-30 | Ajinomoto Co., Inc | METHOD FOR PRODUCING AN ACID SUBSTANCE HAVING A CARBOXYL GROUP |
CN103088081B (en) * | 2013-02-06 | 2014-12-03 | 中粮生化能源(龙江)有限公司 | Biotin supplemented fermentation method for producing glutamic acid |
CN113444655B (en) * | 2020-03-26 | 2023-05-16 | 吉林中粮生化有限公司 | Corynebacterium glutamicum, temperature-sensitive strain with high glutamic acid yield, obtaining method and application thereof, and glutamic acid fermentation method |
CN113292758B (en) * | 2021-05-25 | 2022-06-21 | 南京工业大学 | Shape memory composite material with both electric and temperature response, preparation method thereof and application thereof in immobilized cells |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5224593B2 (en) * | 1973-10-17 | 1977-07-01 | ||
JPS561889A (en) * | 1979-06-20 | 1981-01-10 | Ajinomoto Co Inc | Preparation of l-glutamic acid by fermentation |
JPS57102193A (en) * | 1980-12-17 | 1982-06-25 | Kyowa Hakko Kogyo Co Ltd | Preparation of l-glutamic acid |
JPS62201585A (en) * | 1985-11-26 | 1987-09-05 | Asahi Chem Ind Co Ltd | Dna fragment containing citric acid synthase-producing gene |
FR2590592B1 (en) * | 1985-11-26 | 1989-12-22 | Asahi Chemical Ind | DNA FRAGMENT CONTAINING A GENE ENCODING AN ENZYME CATALYZING A REACTION IN THE TCA CYCLE AND RECOMBINANT DNA CONTAINING THE SAME. |
JPS6244171A (en) * | 1986-08-07 | 1987-02-26 | Kyowa Hakko Kogyo Co Ltd | Novel bacterium capable of producing l-glutamic acid |
JP2578463B2 (en) * | 1988-02-03 | 1997-02-05 | 協和醗酵工業株式会社 | Production method of L-lysine by fermentation method |
JPH029384A (en) * | 1988-06-28 | 1990-01-12 | Kyowa Hakko Kogyo Co Ltd | Production of l-glutamic acid by fermentation process |
JP3245881B2 (en) * | 1990-02-15 | 2002-01-15 | 味の素株式会社 | Simultaneous fermentation of basic and acidic amino acids |
KR0130196B1 (en) * | 1990-02-15 | 1998-04-03 | 도바 다다스 | Method for concurrent fermentation of basic amino acid and acidi amino acid |
-
1995
- 1995-08-09 EP EP02025583A patent/EP1293560B1/en not_active Expired - Lifetime
- 1995-08-09 JP JP8507633A patent/JP2926991B2/en not_active Expired - Fee Related
- 1995-08-09 BR BR9508730A patent/BR9508730A/en not_active Application Discontinuation
- 1995-08-09 WO PCT/JP1995/001586 patent/WO1996006180A1/en active IP Right Grant
- 1995-08-09 EP EP95927999A patent/EP0780477B1/en not_active Expired - Lifetime
- 1995-08-09 DE DE69530306T patent/DE69530306T2/en not_active Expired - Fee Related
- 1995-08-09 US US08/776,597 patent/US5846790A/en not_active Expired - Lifetime
- 1995-08-09 ES ES95927999T patent/ES2191710T3/en not_active Expired - Lifetime
- 1995-08-09 DE DE69535643T patent/DE69535643D1/en not_active Expired - Lifetime
- 1995-08-09 CN CN95195728A patent/CN1079836C/en not_active Expired - Lifetime
- 1995-08-18 PE PE1995276735A patent/PE27597A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1293560A2 (en) | 2003-03-19 |
WO1996006180A1 (en) | 1996-02-29 |
EP1293560A3 (en) | 2004-12-01 |
EP0780477A4 (en) | 1999-06-30 |
BR9508730A (en) | 1997-10-21 |
EP0780477B1 (en) | 2003-04-09 |
US5846790A (en) | 1998-12-08 |
DE69530306D1 (en) | 2003-05-15 |
JP2926991B2 (en) | 1999-07-28 |
PE27597A1 (en) | 1997-08-12 |
EP1293560B1 (en) | 2007-11-14 |
CN1161059A (en) | 1997-10-01 |
ES2191710T3 (en) | 2003-09-16 |
DE69530306T2 (en) | 2003-12-11 |
CN1079836C (en) | 2002-02-27 |
EP0780477A1 (en) | 1997-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |