US4503939A
(en)
*
|
1983-08-19 |
1985-03-12 |
Westinghouse Electric Corp. |
Elevator system
|
ATE547119T1
(de)
|
1997-03-21 |
2012-03-15 |
Chugai Pharmaceutical Co Ltd |
Präventives oder therapeutisches mittel mit einem il-6-antagonisten als wirkstoff für durch sensibilisierte t-zellen vermittelte erkrankungen
|
IT1291932B1
(it)
*
|
1997-06-20 |
1999-01-21 |
Angeletti P Ist Richerche Bio |
Composizioni farmaceutiche antitumorali capaci anche di ridurre la farmacoresistenza in cellule tumorali, in particolare di carcinoma
|
US20020187150A1
(en)
*
|
1997-08-15 |
2002-12-12 |
Chugai Seiyaku Kabushiki Kaisha |
Preventive and/or therapeutic agent for systemic lupus erythematosus comprising anti-IL-6 receptor antibody as an active ingredient
|
DE19818044A1
(de)
*
|
1998-04-22 |
1999-10-28 |
Klinge Co Chem Pharm Fab |
Verwendung von Vitamin-PP-Verbindungen
|
WO2000044407A2
(en)
*
|
1999-02-01 |
2000-08-03 |
Amgen Canada |
Materials and methods to inhibit hodgkin and reed sternberg cell growth
|
UA80091C2
(en)
*
|
2001-04-02 |
2007-08-27 |
Chugai Pharmaceutical Co Ltd |
Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
|
DK1459762T3
(da)
|
2001-11-02 |
2008-10-06 |
Yoshiko Yasuda |
Anvendelse af EMP9 til forebyggelse af proliferative organsygdomme
|
IL161630A0
(en)
*
|
2001-11-06 |
2004-09-27 |
Applied Research Systems |
Methods of treating endometreosis
|
CN100374457C
(zh)
*
|
2001-11-14 |
2008-03-12 |
森托科尔公司 |
抗il-6抗体、组合物、方法和用途
|
EP2338910B1
(de)
*
|
2002-01-18 |
2015-07-08 |
ZymoGenetics, Inc. |
Zytokinrezeptor Zyctor17-Multimere
|
AU2003211990A1
(en)
|
2002-02-14 |
2003-09-04 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody-containing solution pharmaceuticals
|
WO2003090779A1
(fr)
*
|
2002-04-25 |
2003-11-06 |
Chugai Seiyaku Kabushiki Kaisha |
Remede contre le cancer du poumon
|
WO2004045507A2
(en)
*
|
2002-11-15 |
2004-06-03 |
Centocor, Inc. |
Anti-angiogenic uses of il-6 antagonists
|
GB2401040A
(en)
*
|
2003-04-28 |
2004-11-03 |
Chugai Pharmaceutical Co Ltd |
Method for treating interleukin-6 related diseases
|
US20050100550A1
(en)
*
|
2003-11-10 |
2005-05-12 |
Mohit Trikha |
Anti-angiogenic uses of IL-6 antagonists
|
EP3269738A1
(de)
|
2004-03-24 |
2018-01-17 |
Chugai Seiyaku Kabushiki Kaisha |
Subtypen des humanisiertem antikörper gegen interleukin-6-rezeptor
|
US8017395B2
(en)
|
2004-12-17 |
2011-09-13 |
Lifescan, Inc. |
Seeding cells on porous supports
|
PE20061324A1
(es)
*
|
2005-04-29 |
2007-01-15 |
Centocor Inc |
Anticuerpos anti-il-6, composiciones, metodos y usos
|
JP5065253B2
(ja)
|
2005-05-06 |
2012-10-31 |
ザイモジェネティクス, インコーポレイテッド |
Il−31モノクローナル抗体とその使用法
|
US9074189B2
(en)
|
2005-06-08 |
2015-07-07 |
Janssen Biotech, Inc. |
Cellular therapy for ocular degeneration
|
WO2008001851A1
(en)
|
2006-06-28 |
2008-01-03 |
Ihi Corporation |
Drug, drug induction device, magnetic detector and method of designing drug
|
JP2007091710A
(ja)
*
|
2005-08-31 |
2007-04-12 |
Ishikawajima Harima Heavy Ind Co Ltd |
薬、薬の誘導装置、磁気検出装置及び薬の設計方法
|
EP1966244B1
(de)
*
|
2005-12-30 |
2012-03-21 |
Merck Patent GmbH |
Die bindung von mit il-6ralpha komplexiertem il-6 an gp130 verhindernde anti-il-6-antikörper
|
US8741643B2
(en)
|
2006-04-28 |
2014-06-03 |
Lifescan, Inc. |
Differentiation of pluripotent stem cells to definitive endoderm lineage
|
US8080248B2
(en)
|
2006-06-02 |
2011-12-20 |
Regeneron Pharmaceuticals, Inc. |
Method of treating rheumatoid arthritis with an IL-6R antibody
|
ES2398076T3
(es)
|
2006-06-02 |
2013-03-13 |
Regeneron Pharmaceuticals, Inc. |
Anticuerpos de alta afinidad contra el receptor de IL-6 humano
|
EP2064241B1
(de)
*
|
2006-08-03 |
2015-10-07 |
Vaccinex, Inc. |
Monoklonale anti-il-6-antikörper und deren anwendungen
|
WO2008042611A2
(en)
*
|
2006-09-29 |
2008-04-10 |
Centocor, Inc. |
Method of using il6 antagonists with mitoxantrone for prostate cancer
|
US9701747B2
(en)
|
2007-05-21 |
2017-07-11 |
Alderbio Holdings Llc |
Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
|
US8062864B2
(en)
|
2007-05-21 |
2011-11-22 |
Alderbio Holdings Llc |
Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
|
US8178101B2
(en)
*
|
2007-05-21 |
2012-05-15 |
Alderbio Holdings Inc. |
Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
|
SI2164514T1
(sl)
*
|
2007-05-21 |
2017-04-26 |
Alderbio Holdings Llc |
Protitelesa proti IL-6 in njihova uporaba
|
US7906117B2
(en)
*
|
2007-05-21 |
2011-03-15 |
Alderbio Holdings Llc |
Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
|
US8404235B2
(en)
|
2007-05-21 |
2013-03-26 |
Alderbio Holdings Llc |
Antagonists of IL-6 to raise albumin and/or lower CRP
|
CA2688829A1
(en)
*
|
2007-05-21 |
2008-11-27 |
Alder Biopharmaceuticals, Inc. |
Novel rabbit antibody humanization methods and humanized rabbit antibodies
|
US8252286B2
(en)
|
2007-05-21 |
2012-08-28 |
Alderbio Holdings Llc |
Antagonists of IL-6 to prevent or treat thrombosis
|
US20090238825A1
(en)
*
|
2007-05-21 |
2009-09-24 |
Kovacevich Brian R |
Novel rabbit antibody humanization methods and humanized rabbit antibodies
|
US9080145B2
(en)
|
2007-07-01 |
2015-07-14 |
Lifescan Corporation |
Single pluripotent stem cell culture
|
KR101617243B1
(ko)
|
2007-07-31 |
2016-05-02 |
라이프스캔, 인코포레이티드 |
인간 배아 줄기 세포의 분화
|
CN101246160B
(zh)
*
|
2007-09-06 |
2012-11-21 |
三峡大学 |
在体外用ELISA方法建立的IL-6/sIL-6R结合的分子模型
|
KR101601986B1
(ko)
*
|
2007-10-02 |
2016-03-17 |
추가이 세이야쿠 가부시키가이샤 |
인터류킨 6 수용체 저해제를 유효 성분으로 하는 이식편대숙주병 치료제
|
US9062290B2
(en)
|
2007-11-27 |
2015-06-23 |
Lifescan, Inc. |
Differentiation of human embryonic stem cells
|
ME03057B
(de)
|
2007-12-07 |
2019-01-20 |
Zymogenetics Inc |
Für IL-31 spezifische humanisierte Antikörpermoleküle
|
PE20091174A1
(es)
|
2007-12-27 |
2009-08-03 |
Chugai Pharmaceutical Co Ltd |
Formulacion liquida con contenido de alta concentracion de anticuerpo
|
US20090169484A1
(en)
|
2007-12-28 |
2009-07-02 |
Ihi Corporation |
Iron-salen complex
|
AU2009215516B2
(en)
|
2008-02-21 |
2014-12-18 |
Janssen Biotech Inc. |
Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
|
US8623648B2
(en)
|
2008-04-24 |
2014-01-07 |
Janssen Biotech, Inc. |
Treatment of pluripotent cells
|
US8188235B2
(en)
|
2008-06-18 |
2012-05-29 |
Pfizer Inc. |
Antibodies to IL-6 and their uses
|
BRPI0914116A2
(pt)
|
2008-06-30 |
2019-09-17 |
Centocor Ortho Biotech Inc |
diferenciação de células-tronco pluripotentes
|
JP5785088B2
(ja)
|
2008-10-31 |
2015-09-24 |
ヤンセン バイオテツク,インコーポレーテツド |
ヒト胚性幹細胞の膵内分泌系への分化
|
US9012218B2
(en)
|
2008-10-31 |
2015-04-21 |
Janssen Biotech, Inc. |
Differentiation of human embryonic stem cells
|
US8062866B2
(en)
*
|
2008-11-13 |
2011-11-22 |
Femta Pharmaceuticals, Inc. |
Humanized anti-IL-6 antibodies
|
WO2010058280A1
(ja)
|
2008-11-20 |
2010-05-27 |
株式会社Ihi |
自己磁性金属サレン錯体化合物
|
EP2366021B1
(de)
|
2008-11-20 |
2017-08-02 |
Janssen Biotech, Inc. |
Pluripotente stammzellkultur auf mikroträgern
|
CN102257132B
(zh)
|
2008-11-20 |
2014-09-03 |
森托科尔奥索生物科技公司 |
用于在平面基底上进行细胞附着和培养的方法和组合物
|
US8323649B2
(en)
|
2008-11-25 |
2012-12-04 |
Alderbio Holdings Llc |
Antibodies to IL-6 and use thereof
|
US8337847B2
(en)
|
2008-11-25 |
2012-12-25 |
Alderbio Holdings Llc |
Methods of treating anemia using anti-IL-6 antibodies
|
US8992920B2
(en)
|
2008-11-25 |
2015-03-31 |
Alderbio Holdings Llc |
Anti-IL-6 antibodies for the treatment of arthritis
|
US8420089B2
(en)
|
2008-11-25 |
2013-04-16 |
Alderbio Holdings Llc |
Antagonists of IL-6 to raise albumin and/or lower CRP
|
US9452227B2
(en)
*
|
2008-11-25 |
2016-09-27 |
Alderbio Holdings Llc |
Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
|
US9212223B2
(en)
|
2008-11-25 |
2015-12-15 |
Alderbio Holdings Llc |
Antagonists of IL-6 to prevent or treat thrombosis
|
JP5317690B2
(ja)
|
2008-12-27 |
2013-10-16 |
株式会社東芝 |
メモリシステム
|
EP2464666B1
(de)
*
|
2009-07-15 |
2018-03-21 |
Eva Kovacs-Benke |
Kombination aus antagonisten des menschlischen interleukin-6- und antagonisten des menschlischen interleukin-6-rezeptors zur behandlung von krebs
|
SG177483A1
(en)
|
2009-07-20 |
2012-02-28 |
Janssen Biotech Inc |
Differentiation of human embryonic stem cells
|
AU2010276438B2
(en)
|
2009-07-20 |
2015-06-11 |
Janssen Biotech Inc. |
Differentiation of human embryonic stem cells
|
AR077766A1
(es)
|
2009-07-20 |
2011-09-21 |
Janssen Biotech Inc |
Diferenciacion de celulas madre embrionarias humanas
|
BR122022001178B1
(pt)
|
2009-10-26 |
2022-10-04 |
F. Hoffmann-La Roche Ag |
Método para a produção de uma imunoglobulina glicosilada e seu uso
|
WO2011066378A2
(en)
|
2009-11-24 |
2011-06-03 |
Alder Biopharmaceuticals, Inc. |
Antagonists of il-6 to prevent or treat thrombosis
|
US9775921B2
(en)
|
2009-11-24 |
2017-10-03 |
Alderbio Holdings Llc |
Subcutaneously administrable composition containing anti-IL-6 antibody
|
PL2516626T3
(pl)
|
2009-12-23 |
2017-10-31 |
Janssen Biotech Inc |
Różnicowanie ludzkich zarodkowych komórek macierzystych
|
RU2701335C2
(ru)
|
2009-12-23 |
2019-09-25 |
Янссен Байотек, Инк. |
Способ получения популяции панкреатических эндокринных клеток, соэкспрессирующих nkx6.1 и инсулин, и способ лечения диабета
|
JO3417B1
(ar)
|
2010-01-08 |
2019-10-20 |
Regeneron Pharma |
الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
|
JP6013196B2
(ja)
|
2010-03-01 |
2016-10-25 |
ヤンセン バイオテツク,インコーポレーテツド |
多能性幹細胞から誘導した細胞を精製するための方法
|
CA2800610C
(en)
|
2010-05-12 |
2019-09-24 |
Janssen Biotech, Inc. |
Differentiation of human embryonic stem cells
|
PL2578231T3
(pl)
|
2010-05-28 |
2023-01-16 |
Chugai Seiyaku Kabushiki Kaisha |
Środek wzmacniający przeciwnowotworową odpowiedź limfocytów t
|
KR101836850B1
(ko)
|
2010-08-31 |
2018-03-09 |
얀센 바이오테크 인코포레이티드 |
인간 배아 줄기 세포의 분화
|
BR112013004614A2
(pt)
|
2010-08-31 |
2024-01-16 |
Janssen Biotech Inc |
Diferenciação de células-tronco pluripotentes
|
SG10201506855RA
(en)
|
2010-08-31 |
2015-10-29 |
Janssen Biotech Inc |
Differentiation of human embryonic stem cells
|
WO2012064627A2
(en)
|
2010-11-08 |
2012-05-18 |
Genentech, Inc. |
Subcutaneously administered anti-il-6 receptor antibody
|
CA2818813C
(en)
|
2010-11-23 |
2020-10-06 |
Alder Biopharmaceuticals, Inc. |
Anti-il-6 antibodies for the treatment of oral mucositis
|
AR087305A1
(es)
|
2011-07-28 |
2014-03-12 |
Regeneron Pharma |
Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
|
TWI589299B
(zh)
|
2011-10-11 |
2017-07-01 |
再生元醫藥公司 |
用於治療類風濕性關節炎之組成物及其使用方法
|
JO3370B1
(ar)
|
2011-11-10 |
2019-03-13 |
Regeneron Pharma |
طريقة لتثبيط نمو الورم عن طريق تثبيط مستقبل انترلوكين 6
|
SG10201608914WA
(en)
|
2011-12-22 |
2016-12-29 |
Janssen Biotech Inc |
Differentiation of human embryonic stem cells into single hormonal insulin positive cells
|
CN104160018A
(zh)
|
2012-03-07 |
2014-11-19 |
詹森生物科技公司 |
用于扩增和维持多能干细胞的成分确定的培养基
|
BR112014030682A2
(pt)
|
2012-06-08 |
2017-06-27 |
Janssen Biotech Inc |
diferenciação de células tronco embrionárias humanas em células pancreáticas endócrinas
|
US10370644B2
(en)
|
2012-12-31 |
2019-08-06 |
Janssen Biotech, Inc. |
Method for making human pluripotent suspension cultures and cells derived therefrom
|
JP6557146B2
(ja)
|
2012-12-31 |
2019-08-07 |
ヤンセン バイオテツク,インコーポレーテツド |
多能性幹細胞から膵臓内分泌細胞膵臓内分泌細胞への分化のための、空気−液体界面での、ヒト胚性幹細胞の培養
|
RU2684215C2
(ru)
|
2012-12-31 |
2019-04-04 |
Янссен Байотек, Инк. |
Способ получения панкреатических эндокринных клеток (варианты) и способ увеличения выхода бета-клеток
|
SG11201505119UA
(en)
|
2012-12-31 |
2015-07-30 |
Janssen Biotech Inc |
Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells
|
MX363403B
(es)
|
2013-07-04 |
2019-03-22 |
Hoffmann La Roche |
Inmumoensayo con interferencia suprimida para la deteccion de anticuerpos anti-farmacos en muestras de suero.
|
US9017678B1
(en)
|
2014-07-15 |
2015-04-28 |
Kymab Limited |
Method of treating rheumatoid arthritis using antibody to IL6R
|
MX2016015004A
(es)
|
2014-05-16 |
2017-06-27 |
Janssen Biotech Inc |
Uso de moleculas pequeñas para mejorar la expresion de mafa en celulas endocrinas pancreaticas.
|
JP2018523684A
(ja)
|
2015-08-18 |
2018-08-23 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
リポタンパク質アフェレーシスを受けている高脂血症の患者を治療するための抗pcsk9阻害抗体
|
US11484591B2
(en)
|
2016-02-22 |
2022-11-01 |
Ohio State Innovation Foundation |
Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin A analogues or metabolites, and estradiol metabolites
|
MA45479A
(fr)
|
2016-04-14 |
2019-02-20 |
Janssen Biotech Inc |
Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
|
CN110603057A
(zh)
|
2017-03-17 |
2019-12-20 |
俄亥俄州创新基金会 |
用于递送化学预防剂的纳米颗粒
|
CA3128212A1
(en)
|
2019-01-31 |
2020-08-06 |
Sanofi Biotechnology |
Anti-il-6 receptor antibody for treating juvenile idiopathic arthritis
|
EP3947737A2
(de)
|
2019-04-02 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur vorhersage und vorbeugung von krebs bei patienten mit prämalignen läsionen
|