DE69433007D1 - Peptide zum induzieren einer antwort der zytotoxischen t-lymphozyten gerichtet gegen das hepatitis b virus - Google Patents
Peptide zum induzieren einer antwort der zytotoxischen t-lymphozyten gerichtet gegen das hepatitis b virusInfo
- Publication number
- DE69433007D1 DE69433007D1 DE69433007T DE69433007T DE69433007D1 DE 69433007 D1 DE69433007 D1 DE 69433007D1 DE 69433007 T DE69433007 T DE 69433007T DE 69433007 T DE69433007 T DE 69433007T DE 69433007 D1 DE69433007 D1 DE 69433007D1
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- virus
- cytotoxic
- hepatitis
- inducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 241000700721 Hepatitis B virus Species 0.000 title abstract 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/22—Viral peptide or viral protein
- Y10S930/223—Hepatitis related
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2412093A | 1993-02-26 | 1993-02-26 | |
US24120 | 1993-02-26 | ||
PCT/US1994/002195 WO1994019011A1 (en) | 1993-02-26 | 1994-02-25 | Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69433007D1 true DE69433007D1 (de) | 2003-09-11 |
DE69433007T2 DE69433007T2 (de) | 2004-06-09 |
Family
ID=21818965
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1994634954 Expired - Lifetime DE69434954T2 (de) | 1993-02-26 | 1994-02-25 | Peptide zum Induzieren einer Antwort der zytotoxischen T-Lymphozyten gerichtet gegen das Hepatitis-B-Virus |
DE1994633007 Expired - Lifetime DE69433007T2 (de) | 1993-02-26 | 1994-02-25 | Peptide zum induzieren einer antwort der zytotoxischen t-lymphozyten gerichtet gegen das hepatitis b virus |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1994634954 Expired - Lifetime DE69434954T2 (de) | 1993-02-26 | 1994-02-25 | Peptide zum Induzieren einer Antwort der zytotoxischen T-Lymphozyten gerichtet gegen das Hepatitis-B-Virus |
Country Status (11)
Country | Link |
---|---|
US (1) | US5788969A (de) |
EP (2) | EP0687182B1 (de) |
JP (2) | JP3657603B2 (de) |
KR (1) | KR960700745A (de) |
CN (1) | CN1118573A (de) |
AT (1) | ATE359089T1 (de) |
AU (1) | AU695261B2 (de) |
DE (2) | DE69434954T2 (de) |
ES (1) | ES2204912T3 (de) |
NZ (1) | NZ263030A (de) |
WO (1) | WO1994019011A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6607727B1 (en) * | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
US7611713B2 (en) * | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
US6689363B1 (en) | 1992-01-29 | 2004-02-10 | Epimmune Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
US20110097352A9 (en) * | 1992-01-29 | 2011-04-28 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
US6235288B1 (en) * | 1992-08-26 | 2001-05-22 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus |
JP2002509157A (ja) * | 1998-01-19 | 2002-03-26 | モガン バイオテクノロジー リサーチ インスティチュート | B型肝炎ウイルスのxプロテインに由来するペプチド抗原を含むリポソーム |
WO1999058658A2 (en) * | 1998-05-13 | 1999-11-18 | Epimmune, Inc. | Expression vectors for stimulating an immune response and methods of using the same |
US20070020327A1 (en) * | 1998-11-10 | 2007-01-25 | John Fikes | Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions |
EP1244465A4 (de) * | 1999-12-21 | 2005-01-12 | Epimmune Inc | Induzierung von zellulärer immunantwort gegen prostatakrebsantigenen mittels peptid- und nukleinsäureverbindungen |
KR100455902B1 (ko) * | 2001-07-18 | 2004-11-12 | 주식회사 펩트론 | B형 간염 바이러스 표면단백질 프리에스-1 유래의 펩타이드 |
CN1305527C (zh) * | 2003-11-21 | 2007-03-21 | 薛平 | 乙型肝炎治疗疫苗及其制备方法 |
JP2008533114A (ja) * | 2005-03-18 | 2008-08-21 | ユーシーエル ビジネス パブリック リミテッド カンパニー | メカノ成長因子ペプチドおよびその使用 |
US20090023895A1 (en) * | 2006-02-07 | 2009-01-22 | Nec Corporation | Hla-binding peptide, precursor thereof, and dna fragment and recombinant vector coding for said hla-binding peptide |
US8324345B2 (en) | 2006-10-12 | 2012-12-04 | Nec Corporation | HLA-binding peptide, precursor thereof, DNA fragment and recombinant vector encoding the same |
US20110110974A1 (en) * | 2007-10-29 | 2011-05-12 | Erik Depla | Methods and kits for inducing a ctl response using a prime boost regimen |
WO2010086294A2 (en) | 2009-01-28 | 2010-08-05 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
US10076570B2 (en) | 2009-08-07 | 2018-09-18 | Transgene S.A. | Composition for treating HBV infection |
EP2461826A2 (de) | 2009-08-07 | 2012-06-13 | Transgene SA | Zusammensetzung zur behandlung von hbv-infektionen |
TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Hbv聚合酶突變體 |
EP3522920A2 (de) | 2016-10-10 | 2019-08-14 | Transgene SA | Immuntherapeutisches produkt und mdsc-modulator-kombinationstherapie |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816564A (en) * | 1986-01-31 | 1989-03-28 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
EP0293201A3 (de) * | 1987-05-26 | 1990-02-28 | The Wistar Institute | Methode zur Impfung gegen Hepatitis-B-Virus |
EP0326111A3 (de) * | 1988-01-29 | 1989-12-27 | New York Blood Center, Inc. | Peptid-Derivate, immunogenisch gemacht bei Verabreichung zusammen mit Alaun als Zusatzmittel |
CA2157510A1 (en) * | 1993-03-05 | 1994-09-15 | Howard M. Grey | Hla-a2.1 binding peptides and their uses |
ES2180576T3 (es) * | 1993-04-27 | 2003-02-16 | United Biomedical Inc | Construcciones peptidicas de lhrh inmunogenicas y estimuladores de inmunidad universales sinteticos para vacunas. |
DE69430315T2 (de) * | 1993-08-06 | 2002-11-21 | Epimmune, Inc. | Methoden zur (ex vivo) therapie mittels peptid - bestueckten antigen - praesentierenden zellen zur aktivierung von ctl |
-
1994
- 1994-02-25 KR KR1019950703607A patent/KR960700745A/ko not_active Application Discontinuation
- 1994-02-25 EP EP19940910791 patent/EP0687182B1/de not_active Expired - Lifetime
- 1994-02-25 NZ NZ263030A patent/NZ263030A/en not_active IP Right Cessation
- 1994-02-25 JP JP51934194A patent/JP3657603B2/ja not_active Expired - Fee Related
- 1994-02-25 AT AT03010010T patent/ATE359089T1/de not_active IP Right Cessation
- 1994-02-25 DE DE1994634954 patent/DE69434954T2/de not_active Expired - Lifetime
- 1994-02-25 DE DE1994633007 patent/DE69433007T2/de not_active Expired - Lifetime
- 1994-02-25 AU AU63559/94A patent/AU695261B2/en not_active Ceased
- 1994-02-25 CN CN94191295A patent/CN1118573A/zh active Pending
- 1994-02-25 ES ES94910791T patent/ES2204912T3/es not_active Expired - Lifetime
- 1994-02-25 EP EP20030010010 patent/EP1375511B1/de not_active Expired - Lifetime
- 1994-02-25 WO PCT/US1994/002195 patent/WO1994019011A1/en active IP Right Grant
-
1995
- 1995-06-05 US US08/464,235 patent/US5788969A/en not_active Expired - Lifetime
-
2004
- 2004-01-05 JP JP2004000504A patent/JP3616390B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3616390B2 (ja) | 2005-02-02 |
EP0687182A1 (de) | 1995-12-20 |
EP1375511B1 (de) | 2007-04-11 |
DE69434954D1 (de) | 2007-05-24 |
EP1375511A2 (de) | 2004-01-02 |
EP0687182A4 (de) | 1997-03-12 |
US5788969A (en) | 1998-08-04 |
EP1375511A3 (de) | 2005-03-02 |
DE69433007T2 (de) | 2004-06-09 |
DE69434954T2 (de) | 2007-12-20 |
JP2004161778A (ja) | 2004-06-10 |
JPH08507080A (ja) | 1996-07-30 |
AU6355994A (en) | 1994-09-14 |
CN1118573A (zh) | 1996-03-13 |
WO1994019011A1 (en) | 1994-09-01 |
NZ263030A (en) | 1997-10-24 |
EP0687182B1 (de) | 2003-08-06 |
ES2204912T3 (es) | 2004-05-01 |
JP3657603B2 (ja) | 2005-06-08 |
AU695261B2 (en) | 1998-08-13 |
KR960700745A (ko) | 1996-02-24 |
ATE359089T1 (de) | 2007-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |