DE69411000T2 - Verfahren zur herstellung von beta-phenylisoserin-derivaten - Google Patents
Verfahren zur herstellung von beta-phenylisoserin-derivatenInfo
- Publication number
- DE69411000T2 DE69411000T2 DE69411000T DE69411000T DE69411000T2 DE 69411000 T2 DE69411000 T2 DE 69411000T2 DE 69411000 T DE69411000 T DE 69411000T DE 69411000 T DE69411000 T DE 69411000T DE 69411000 T2 DE69411000 T2 DE 69411000T2
- Authority
- DE
- Germany
- Prior art keywords
- radical
- pct
- optionally substituted
- general formula
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9303575A FR2703353B1 (fr) | 1993-03-29 | 1993-03-29 | Procédé de préparation de dérivés de la beta-phénylisosérine. |
PCT/FR1994/000339 WO1994022813A1 (fr) | 1993-03-29 | 1994-03-25 | PROCEDE DE PREPARATION DE DERIVES DE LA β-PHENYLISOSERINE |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69411000D1 DE69411000D1 (de) | 1998-07-16 |
DE69411000T2 true DE69411000T2 (de) | 1998-12-03 |
Family
ID=9445442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69411000T Expired - Lifetime DE69411000T2 (de) | 1993-03-29 | 1994-03-25 | Verfahren zur herstellung von beta-phenylisoserin-derivaten |
Country Status (10)
Country | Link |
---|---|
US (1) | US5681970A (de) |
EP (1) | EP0691951B1 (de) |
JP (1) | JP3633619B2 (de) |
AT (1) | ATE167179T1 (de) |
CA (1) | CA2158060C (de) |
DE (1) | DE69411000T2 (de) |
DK (1) | DK0691951T3 (de) |
ES (1) | ES2118394T3 (de) |
FR (1) | FR2703353B1 (de) |
WO (1) | WO1994022813A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69433297T2 (de) * | 1993-02-05 | 2004-10-21 | Bryn Mawr College Bryn Mawr | Synthese von taxol, seinen analogen und intermediaten mit variablen a-ring seitenketten |
KR100225534B1 (ko) * | 1996-03-19 | 1999-10-15 | 정지석 | (2R,3S)-베타-페닐이소세린 유도체의 입체선택적 제조방법[Storcospecific process for preparing(2R,3S)-β0phenylisoserine] |
US6025516A (en) * | 1998-10-14 | 2000-02-15 | Chiragene, Inc. | Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes |
US6847778B1 (en) | 1999-03-30 | 2005-01-25 | Tivo, Inc. | Multimedia visual progress indication system |
EP2266607A3 (de) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunokonjugate für Krebsbehandlung |
US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
US20110223154A1 (en) * | 2008-05-12 | 2011-09-15 | University Of South Florida | Compositions including triciribine and methods of use thereof |
US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
SI2574341T1 (sl) | 2004-03-29 | 2017-08-31 | University Of South Florida | Učinkovito zdravljenje tumorjev in raka s triciribin fosfatom |
US20100009928A1 (en) * | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
CA2724246C (en) | 2008-05-12 | 2019-11-26 | University Of South Florida | Anticancer combination therapy including triciribine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2023645C (fr) * | 1989-08-23 | 2002-03-26 | Jean-Noel Denis | Procede pour la preparation enantioselective de derives de la phenylisoserine |
MX9102128A (es) | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
-
1993
- 1993-03-29 FR FR9303575A patent/FR2703353B1/fr not_active Expired - Lifetime
-
1994
- 1994-03-25 ES ES94911225T patent/ES2118394T3/es not_active Expired - Lifetime
- 1994-03-25 AT AT94911225T patent/ATE167179T1/de active
- 1994-03-25 DK DK94911225T patent/DK0691951T3/da active
- 1994-03-25 WO PCT/FR1994/000339 patent/WO1994022813A1/fr active IP Right Grant
- 1994-03-25 JP JP52174294A patent/JP3633619B2/ja not_active Expired - Lifetime
- 1994-03-25 DE DE69411000T patent/DE69411000T2/de not_active Expired - Lifetime
- 1994-03-25 US US08/525,786 patent/US5681970A/en not_active Expired - Lifetime
- 1994-03-25 CA CA002158060A patent/CA2158060C/fr not_active Expired - Lifetime
- 1994-03-25 EP EP94911225A patent/EP0691951B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK0691951T3 (da) | 1998-10-19 |
FR2703353B1 (fr) | 1995-05-05 |
CA2158060A1 (fr) | 1994-10-13 |
WO1994022813A1 (fr) | 1994-10-13 |
ES2118394T3 (es) | 1998-09-16 |
FR2703353A1 (fr) | 1994-10-07 |
DE69411000D1 (de) | 1998-07-16 |
US5681970A (en) | 1997-10-28 |
EP0691951B1 (de) | 1998-06-10 |
JPH08508281A (ja) | 1996-09-03 |
EP0691951A1 (de) | 1996-01-17 |
CA2158060C (fr) | 2006-11-21 |
ATE167179T1 (de) | 1998-06-15 |
JP3633619B2 (ja) | 2005-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: AVENTIS PHARMA S.A., ANTONY, FR |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |