DE69401286D1 - Verfahren zur Reinigung von Estramustin Phosfat oder Salze davon - Google Patents

Verfahren zur Reinigung von Estramustin Phosfat oder Salze davon

Info

Publication number
DE69401286D1
DE69401286D1 DE69401286T DE69401286T DE69401286D1 DE 69401286 D1 DE69401286 D1 DE 69401286D1 DE 69401286 T DE69401286 T DE 69401286T DE 69401286 T DE69401286 T DE 69401286T DE 69401286 D1 DE69401286 D1 DE 69401286D1
Authority
DE
Germany
Prior art keywords
purification
salts
estramustine phosphate
estramustine
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69401286T
Other languages
English (en)
Other versions
DE69401286T2 (de
Inventor
Keiji Ohwaki
Satoru Norose
Hideki Niino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Permachem Asia Ltd
Original Assignee
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permachem Asia Ltd filed Critical Permachem Asia Ltd
Publication of DE69401286D1 publication Critical patent/DE69401286D1/de
Application granted granted Critical
Publication of DE69401286T2 publication Critical patent/DE69401286T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69401286T 1993-02-18 1994-02-16 Verfahren zur Reinigung von Estramustin Phosfat oder Salze davon Expired - Lifetime DE69401286T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5051288A JP2554005B2 (ja) 1993-02-18 1993-02-18 エストラムスチンフォスフェート又はその塩類の精製方法

Publications (2)

Publication Number Publication Date
DE69401286D1 true DE69401286D1 (de) 1997-02-13
DE69401286T2 DE69401286T2 (de) 1997-04-30

Family

ID=12882750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69401286T Expired - Lifetime DE69401286T2 (de) 1993-02-18 1994-02-16 Verfahren zur Reinigung von Estramustin Phosfat oder Salze davon

Country Status (3)

Country Link
EP (1) EP0612760B1 (de)
JP (1) JP2554005B2 (de)
DE (1) DE69401286T2 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299104A (en) * 1963-04-09 1967-01-17 Leo Ab Certain steroid nu-bis-(haloethyl)-carbamates
GB1523035A (en) * 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
SE8305596D0 (sv) * 1983-10-12 1983-10-12 Leo Ab A selective acylation method

Also Published As

Publication number Publication date
JPH06239882A (ja) 1994-08-30
EP0612760A2 (de) 1994-08-31
EP0612760A3 (de) 1995-08-30
EP0612760B1 (de) 1997-01-02
DE69401286T2 (de) 1997-04-30
JP2554005B2 (ja) 1996-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition