DE69305643T2 - 4-oxa-1-azabicyclo(3,2,0)heptan-7-one -derivate als antitumorwirkstoffe - Google Patents

4-oxa-1-azabicyclo(3,2,0)heptan-7-one -derivate als antitumorwirkstoffe

Info

Publication number
DE69305643T2
DE69305643T2 DE69305643T DE69305643T DE69305643T2 DE 69305643 T2 DE69305643 T2 DE 69305643T2 DE 69305643 T DE69305643 T DE 69305643T DE 69305643 T DE69305643 T DE 69305643T DE 69305643 T2 DE69305643 T2 DE 69305643T2
Authority
DE
Germany
Prior art keywords
antituary
heptan
azabicyclo
oxa
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69305643T
Other languages
English (en)
Other versions
DE69305643D1 (en
Inventor
Toshio Otani
Shinji Oie
Hiroshi Matsumoto
Mark Tempest
Ronald Micetich
Rajeshwar Singh
Tomohiro Yamashita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synphar Laboratories Inc
Taiho Pharmaceutical Co Ltd
Original Assignee
Synphar Laboratories Inc
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synphar Laboratories Inc, Taiho Pharmaceutical Co Ltd filed Critical Synphar Laboratories Inc
Application granted granted Critical
Publication of DE69305643D1 publication Critical patent/DE69305643D1/de
Publication of DE69305643T2 publication Critical patent/DE69305643T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69305643T 1992-07-09 1993-07-08 4-oxa-1-azabicyclo(3,2,0)heptan-7-one -derivate als antitumorwirkstoffe Expired - Fee Related DE69305643T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929214603A GB9214603D0 (en) 1992-07-09 1992-07-09 4-oxa-1-azabicyclo (3,2,0) heptan-7-one derivatives as antitumor agents
PCT/GB1993/001435 WO1994001109A1 (en) 1992-07-09 1993-07-08 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents

Publications (2)

Publication Number Publication Date
DE69305643D1 DE69305643D1 (en) 1996-11-28
DE69305643T2 true DE69305643T2 (de) 1997-05-07

Family

ID=10718456

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69305643T Expired - Fee Related DE69305643T2 (de) 1992-07-09 1993-07-08 4-oxa-1-azabicyclo(3,2,0)heptan-7-one -derivate als antitumorwirkstoffe

Country Status (12)

Country Link
US (1) US5561126A (de)
EP (1) EP0654995B1 (de)
JP (1) JPH07508982A (de)
KR (1) KR100283683B1 (de)
AU (1) AU679687B2 (de)
CA (1) CA2139633A1 (de)
DE (1) DE69305643T2 (de)
ES (1) ES2096931T3 (de)
FI (1) FI950101A (de)
GB (1) GB9214603D0 (de)
HU (1) HUT70162A (de)
WO (1) WO1994001109A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9400220D0 (en) * 1994-01-07 1994-03-02 Taiho Pharmaceutical Co Ltd Novel 3-(substituted methyl)-4-oxa-1-azabicycle (3.2.0) heptan-7-one derivatives useful as antitumor agents
US5925633A (en) * 1996-03-06 1999-07-20 Synphar Laboraties, Inc. 3-Substituted-4-oxa-1-azabicyclo 3,2,0!heptan-7-one as cysteine protease inhibitors
US6703384B2 (en) 1998-09-23 2004-03-09 Research Development Foundation Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1515241A (en) * 1976-01-27 1978-06-21 Beecham Group Ltd Beta-lactam antibiotics
JPS61212587A (ja) * 1985-03-18 1986-09-20 Taiho Yakuhin Kogyo Kk Ｇ００６９ａ物質

Also Published As

Publication number Publication date
CA2139633A1 (en) 1994-01-20
WO1994001109A1 (en) 1994-01-20
EP0654995A1 (de) 1995-05-31
AU4511293A (en) 1994-01-31
ES2096931T3 (es) 1997-03-16
FI950101A (fi) 1995-03-07
KR100283683B1 (ko) 2001-03-02
HUT70162A (en) 1995-09-28
AU679687B2 (en) 1997-07-10
JPH07508982A (ja) 1995-10-05
HU9500029D0 (en) 1995-03-28
GB9214603D0 (en) 1992-08-19
DE69305643D1 (en) 1996-11-28
US5561126A (en) 1996-10-01
FI950101A0 (fi) 1995-01-09
EP0654995B1 (de) 1996-10-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee