DE69226432D1 - 2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellung - Google Patents
2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellungInfo
- Publication number
- DE69226432D1 DE69226432D1 DE69226432T DE69226432T DE69226432D1 DE 69226432 D1 DE69226432 D1 DE 69226432D1 DE 69226432 T DE69226432 T DE 69226432T DE 69226432 T DE69226432 T DE 69226432T DE 69226432 D1 DE69226432 D1 DE 69226432D1
- Authority
- DE
- Germany
- Prior art keywords
- spirocyclopropyl
- acylcephalosporine
- production
- useful
- acylcephem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/681,680 US5258377A (en) | 1991-04-08 | 1991-04-08 | 2-spirocyclopropyl 4-acylcephems |
PCT/CA1992/000145 WO1992017482A1 (en) | 1991-04-08 | 1992-04-07 | Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69226432D1 true DE69226432D1 (de) | 1998-09-03 |
Family
ID=24736298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69226432T Expired - Lifetime DE69226432D1 (de) | 1991-04-08 | 1992-04-07 | 2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellung |
Country Status (10)
Country | Link |
---|---|
US (1) | US5258377A (de) |
EP (1) | EP0580650B1 (de) |
JP (1) | JPH06506207A (de) |
AT (1) | ATE169023T1 (de) |
CA (1) | CA2107892A1 (de) |
DE (1) | DE69226432D1 (de) |
FI (1) | FI934395A (de) |
HU (1) | HUT66046A (de) |
WO (1) | WO1992017482A1 (de) |
ZA (1) | ZA922504B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8811388D0 (en) * | 1988-05-13 | 1988-06-15 | Erba Carlo Spa | 1,1-dioxo-cephem-4-carbothiolic acid derivatives |
GB8928373D0 (en) * | 1989-12-15 | 1990-02-21 | Erba Carlo Spa | Beta-lactam derivatives |
US5439904A (en) * | 1993-12-07 | 1995-08-08 | Synphar Laboratories, Inc. | 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents |
US5597817A (en) * | 1994-12-09 | 1997-01-28 | Southern Methodist University | 7-vinylidene cephalosporins and methods of using the same |
US5629306A (en) | 1994-12-09 | 1997-05-13 | Research Corporation Technologies, Inc. | 7-alkylidene cephalosporanic acid derivatives and methods of using the same |
US5760027A (en) * | 1996-12-06 | 1998-06-02 | Research Corporation Technologies, Inc. | Use of 7-alkylidene cephalosporins to inhibit elastase activity |
US6407091B1 (en) * | 1999-04-15 | 2002-06-18 | Research Corporation Technologies, Inc. | β-lactamase inhibiting compounds |
EP1660506A4 (de) * | 2003-08-25 | 2009-02-25 | Revaax Pharmaceuticals Llc | Orale neurotherapeutische cefazolinzusammensetzungen |
WO2019038412A1 (en) | 2017-08-24 | 2019-02-28 | Novo Nordisk A/S | GLP-1 COMPOSITIONS AND USES THEREOF |
BR112022013746A2 (pt) | 2020-02-18 | 2022-10-11 | Novo Nordisk As | Formulação aquosa de cagrilintida, formulação aquosa de semaglutida, dispositivo médico, e, combinação de dose fixa |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH563396A5 (de) * | 1970-06-05 | 1975-06-30 | Ciba Geigy Ag | |
US4547371A (en) * | 1983-04-18 | 1985-10-15 | Merck & Co., Inc. | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
EP0124081A3 (de) * | 1983-05-02 | 1986-11-26 | Merck & Co. Inc. | Substituierte Cephalosporinsulfone mit Antientzündungs- und Antidegenerativwirkung, sie enthaltende Zusammensetzungen und Verfahren zur Herstellung |
US4717722A (en) * | 1984-05-07 | 1988-01-05 | Merck & Co., Inc. | Substituted 1-oxa-dethiacephalosporins as anti-inflammatory and antidegenerative agents |
EP0267723B1 (de) * | 1986-11-12 | 1996-02-07 | Merck & Co. Inc. | Substituierte Cephalosporinsulfone als anti-entzündliche und anti-degenerative Mittel |
JPH01226887A (ja) * | 1988-03-07 | 1989-09-11 | Takeda Chem Ind Ltd | 3環性セファムまたはイソセファム化合物,その製造法およびエラスターゼ阻害剤 |
GB8808701D0 (en) * | 1988-04-13 | 1988-05-18 | Erba Carlo Spa | Beta-lactam derivatives |
GB8811388D0 (en) * | 1988-05-13 | 1988-06-15 | Erba Carlo Spa | 1,1-dioxo-cephem-4-carbothiolic acid derivatives |
JPH05503290A (ja) * | 1989-10-06 | 1993-06-03 | シンファー ラボラトリーズ,インコーポレーティッド | 新規2―スピロシクロプロピルセファロスポリンスルホン誘導体およびそれらの製造法 |
-
1991
- 1991-04-08 US US07/681,680 patent/US5258377A/en not_active Expired - Fee Related
-
1992
- 1992-04-07 DE DE69226432T patent/DE69226432D1/de not_active Expired - Lifetime
- 1992-04-07 WO PCT/CA1992/000145 patent/WO1992017482A1/en active IP Right Grant
- 1992-04-07 EP EP92907957A patent/EP0580650B1/de not_active Expired - Lifetime
- 1992-04-07 JP JP4507471A patent/JPH06506207A/ja active Pending
- 1992-04-07 AT AT92907957T patent/ATE169023T1/de not_active IP Right Cessation
- 1992-04-07 ZA ZA922504A patent/ZA922504B/xx unknown
- 1992-04-07 HU HU9302717A patent/HUT66046A/hu unknown
- 1992-04-07 CA CA002107892A patent/CA2107892A1/en not_active Abandoned
-
1993
- 1993-10-06 FI FI934395A patent/FI934395A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUT66046A (en) | 1994-09-28 |
US5258377A (en) | 1993-11-02 |
AU668503B2 (en) | 1996-05-09 |
EP0580650B1 (de) | 1998-07-29 |
JPH06506207A (ja) | 1994-07-14 |
ZA922504B (en) | 1993-12-07 |
EP0580650A1 (de) | 1994-02-02 |
AU1556092A (en) | 1992-11-02 |
ATE169023T1 (de) | 1998-08-15 |
FI934395A0 (fi) | 1993-10-06 |
WO1992017482A1 (en) | 1992-10-15 |
HU9302717D0 (en) | 1993-12-28 |
FI934395A (fi) | 1993-10-21 |
CA2107892A1 (en) | 1992-10-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |