DE69131319T2 - Isoliertes PCTD Plasmid aus Chlamydia trachomatis von Serotyp D, dessen Genen und davon kodierten Proteine, rekombinante Plasmide für die Expression von deren Genen als Fusionsproteine in einem keterologen System, und ihre Verwendung als Impfstoff- und/oder Diagnostiekformulierung - Google Patents
Isoliertes PCTD Plasmid aus Chlamydia trachomatis von Serotyp D, dessen Genen und davon kodierten Proteine, rekombinante Plasmide für die Expression von deren Genen als Fusionsproteine in einem keterologen System, und ihre Verwendung als Impfstoff- und/oder DiagnostiekformulierungInfo
- Publication number
- DE69131319T2 DE69131319T2 DE69131319T DE69131319T DE69131319T2 DE 69131319 T2 DE69131319 T2 DE 69131319T2 DE 69131319 T DE69131319 T DE 69131319T DE 69131319 T DE69131319 T DE 69131319T DE 69131319 T2 DE69131319 T2 DE 69131319T2
- Authority
- DE
- Germany
- Prior art keywords
- genes
- plasmid
- isolated
- keterological
- pctd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 239000013612 plasmid Substances 0.000 title abstract 3
- 241000606153 Chlamydia trachomatis Species 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 229940038705 chlamydia trachomatis Drugs 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/125—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Chlamydiales (O)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910314A IT1244706B (it) | 1991-02-07 | 1991-02-07 | Plasmide pctd isolato da chlamydia trachomatis serotipo d, suoi geni e proteine da essi codificate; plasmidi ricombinanti per l'espressionedi detti geni in sistemi eterologhi come proteine ricombinanti di fusione, preparazione di dette proteine ricombinanti e loro uso nella formulazione di vaccini e/o diagnostici |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69131319D1 DE69131319D1 (de) | 1999-07-15 |
DE69131319T2 true DE69131319T2 (de) | 1999-12-16 |
Family
ID=11358472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69131319T Expired - Lifetime DE69131319T2 (de) | 1991-02-07 | 1991-04-17 | Isoliertes PCTD Plasmid aus Chlamydia trachomatis von Serotyp D, dessen Genen und davon kodierten Proteine, rekombinante Plasmide für die Expression von deren Genen als Fusionsproteine in einem keterologen System, und ihre Verwendung als Impfstoff- und/oder Diagnostiekformulierung |
Country Status (8)
Country | Link |
---|---|
US (2) | US6110705A (de) |
EP (1) | EP0499681B1 (de) |
AT (1) | ATE181104T1 (de) |
DE (1) | DE69131319T2 (de) |
DK (1) | DK0499681T3 (de) |
ES (1) | ES2136062T3 (de) |
GR (1) | GR3030447T3 (de) |
IT (1) | IT1244706B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5629167A (en) * | 1994-04-19 | 1997-05-13 | Biocine S.P.A. | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
US5814490A (en) * | 1996-06-11 | 1998-09-29 | Becton, Dickinson And Company | Amplification and detection of chlamydia trachomatis nucleic acids |
IL119938A (en) * | 1996-12-30 | 2005-08-31 | Yissum Res Dev Co | Peptides capable of eliciting protective immunity against toxic shock induced by pyrogenic exotoxins or of antagonizing toxin-mediated activation of t cells |
GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
US7090973B1 (en) * | 1999-04-09 | 2006-08-15 | Oscient Pharmaceuticals Corporation | Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics |
GB0016814D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (3) |
EP2168596B1 (de) | 2001-12-12 | 2012-05-23 | Novartis Vaccines and Diagnostics S.r.l. | Immunisierung gegen Chlamydia trachomatis |
AU2008246064A1 (en) | 2007-05-01 | 2008-11-06 | The Board Of Regents Of The University Of Texas System | Chlamydial antigens as reagents for diagnosis and treatment of chlamydial infection and disease |
US9068007B2 (en) | 2008-10-09 | 2015-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3650571T2 (de) * | 1985-01-14 | 1997-02-27 | Chiron Corp | Hauptprotein der Aussenmembran von Chlamydia |
GB8709746D0 (en) * | 1987-04-24 | 1987-05-28 | Wenman W M | Chlamydia vaccine |
IT1224253B (it) * | 1988-04-08 | 1990-09-26 | Sclavo Spa | Oligonucleotidi sintetici utili per la determinazione di chlamydia trachomatis in un campione biologico |
-
1991
- 1991-02-07 IT ITMI910314A patent/IT1244706B/it active IP Right Grant
- 1991-04-17 ES ES91106110T patent/ES2136062T3/es not_active Expired - Lifetime
- 1991-04-17 EP EP91106110A patent/EP0499681B1/de not_active Expired - Lifetime
- 1991-04-17 DK DK91106110T patent/DK0499681T3/da active
- 1991-04-17 DE DE69131319T patent/DE69131319T2/de not_active Expired - Lifetime
- 1991-04-17 AT AT91106110T patent/ATE181104T1/de not_active IP Right Cessation
-
1995
- 1995-05-18 US US08/444,189 patent/US6110705A/en not_active Expired - Lifetime
-
1997
- 1997-11-13 US US08/969,644 patent/US6096519A/en not_active Expired - Fee Related
-
1999
- 1999-06-10 GR GR990401491T patent/GR3030447T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US6096519A (en) | 2000-08-01 |
ATE181104T1 (de) | 1999-06-15 |
ES2136062T3 (es) | 1999-11-16 |
ITMI910314A0 (it) | 1991-02-07 |
ITMI910314A1 (it) | 1992-08-07 |
EP0499681A1 (de) | 1992-08-26 |
DK0499681T3 (da) | 1999-11-15 |
IT1244706B (it) | 1994-08-08 |
EP0499681B1 (de) | 1999-06-09 |
US6110705A (en) | 2000-08-29 |
GR3030447T3 (en) | 1999-09-30 |
DE69131319D1 (de) | 1999-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |