DE69130869T2 - Xanthinderivate - Google Patents

Xanthinderivate

Info

Publication number
DE69130869T2
DE69130869T2 DE69130869T DE69130869T DE69130869T2 DE 69130869 T2 DE69130869 T2 DE 69130869T2 DE 69130869 T DE69130869 T DE 69130869T DE 69130869 T DE69130869 T DE 69130869T DE 69130869 T2 DE69130869 T2 DE 69130869T2
Authority
DE
Germany
Prior art keywords
represents hydrogen
different
same
formula
xantine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130869T
Other languages
English (en)
Other versions
DE69130869D1 (en
Inventor
Fumio Suzuki
Junichi Shimada
Akio Ishii
Hiromi Nonaka
Nobuo Kosaka
Shunji Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69130869D1 publication Critical patent/DE69130869D1/de
Publication of DE69130869T2 publication Critical patent/DE69130869T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Led Devices (AREA)
DE69130869T 1990-10-18 1991-10-17 Xanthinderivate Expired - Fee Related DE69130869T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28017190 1990-10-18
PCT/JP1991/001420 WO1992006976A1 (fr) 1990-10-18 1991-10-17 Derive de xanthine

Publications (2)

Publication Number Publication Date
DE69130869D1 DE69130869D1 (en) 1999-03-18
DE69130869T2 true DE69130869T2 (de) 1999-06-10

Family

ID=17621294

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130869T Expired - Fee Related DE69130869T2 (de) 1990-10-18 1991-10-17 Xanthinderivate

Country Status (6)

Country Link
EP (1) EP0559893B1 (de)
AT (1) ATE176470T1 (de)
CA (1) CA2094270C (de)
DE (1) DE69130869T2 (de)
ES (1) ES2130138T3 (de)
WO (1) WO1992006976A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2093403C (en) * 1992-04-08 1999-08-10 Fumio Suzuki Therapeutic agent for parkinson's disease
US5484920A (en) * 1992-04-08 1996-01-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for Parkinson's disease
US5543415A (en) * 1992-07-08 1996-08-06 Kyowa Hakko Kogyo Co., Ltd. Antidepressants
TW252044B (de) * 1992-08-10 1995-07-21 Boehringer Ingelheim Kg
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
CA2112031A1 (en) * 1992-12-24 1994-06-25 Fumio Suzuki Xanthine derivatives
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
ES2070087B1 (es) * 1993-08-13 1996-02-16 Pfizer Derivados de indol
US5703085A (en) * 1994-02-23 1997-12-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
ATE325610T1 (de) 1997-09-05 2006-06-15 Kyowa Hakko Kogyo Kk Xanthinderivative zur behandlung von hirnischämie
CA2315736A1 (en) * 1998-01-05 1999-07-15 Eisai Co., Ltd. Purine compounds and adenosine a2 receptor antagonist as preventive or therapeutic for diabetes mellitus
ES2260061T3 (es) * 1999-10-29 2006-11-01 Kyowa Hakko Kogyo Co., Ltd. Composiciones farmaceuticas para trastornos relacionados con la alimentacion.
FR2804958B1 (fr) * 2000-02-15 2005-07-08 Hoechst Marion Roussel Inc Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant
KR20150080013A (ko) 2002-01-28 2015-07-08 교와 핫꼬 기린 가부시키가이샤 운동성 질환에 걸린 환자의 치료용 조성물
US20060122198A1 (en) * 2003-06-27 2006-06-08 Kyowa Hakko Kogyo Co., Ltd. Antiepileptic agent
JP4714024B2 (ja) * 2004-01-28 2011-06-29 協和発酵キリン株式会社 片頭痛の治療剤
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
WO2008070529A2 (en) * 2006-12-01 2008-06-12 Cv Therapeutics, Inc. A2a adenosine receptor antagonists
KR20090094465A (ko) * 2006-12-22 2009-09-07 슈바르츠 파르마 악티엔게젤샤프트 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체
RU2477726C1 (ru) * 2011-10-18 2013-03-20 Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение
WO2020125779A1 (en) * 2018-12-21 2020-06-25 Sunshine Lake Pharma Co., Ltd. 8-substituted styryl xanthine derivatives and uses thereof
CN111072663B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111018856B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0423805B1 (de) * 1989-10-20 2000-08-23 Kyowa Hakko Kogyo Kabushiki Kaisha Kondensierte Purinderivate

Also Published As

Publication number Publication date
CA2094270C (en) 1997-01-21
ES2130138T3 (es) 1999-07-01
EP0559893B1 (de) 1999-02-03
CA2094270A1 (en) 1992-04-19
EP0559893A1 (de) 1993-09-15
ATE176470T1 (de) 1999-02-15
WO1992006976A1 (fr) 1992-04-30
DE69130869D1 (en) 1999-03-18
EP0559893A4 (en) 1994-07-06

Similar Documents

Publication Publication Date Title
DE69130869T2 (de) Xanthinderivate
DK0784974T3 (da) Fremstilling af xanthinderivater i fast dispersion
DE69839735D1 (de) Pyrimidin-5-carboxamid-derivate
DE69628804D1 (de) Substitutierte heterozyclische Derivate als CRF Antagonisten
ATE229012T1 (de) Neue taxanderivate
ATE105285T1 (de) Salicylaldehyd- und salicylsaeurederivate sowie deren schwefelanaloge, verfahren zu ihrer herstellung und ihre verwendung als herbizide und bioregulatoren.
DE69127791D1 (de) Diazabicyclononyl-Derivate als 5-HT3 Rezeptor Antagonisten
EP0358190A3 (de) Polysiloxane mit sterisch gehinderten Gruppen
DE69027235D1 (de) Xanthinderivate
HUT47789A (en) Compositions containing n-/dihalogeno-acetyl/-oxazolidine derivatives as antidotum substituted with heterocyclic group at the 5-position
ATE237612T1 (de) Benzofuranderivate
DE69731556D1 (de) Fettemulsion, die ein xanthinderivat enthält
EP0371805A3 (de) Piperidin-Derivate und diese enthaltende Hypotensiva
ATE112567T1 (de) Imidazo(4,5-c>pyridine als paf antagonisten.
IT8719814A0 (it) Composti triazinici derivati dalla 2,2,6,6-tetrametilpiperidina.
DE3264253D1 (de) Pyridine derivatives as histamine h2 antagonists
EP0884318A4 (de) Kondensierte purinderivate
EP0579836A4 (de)
WO1997020814A1 (fr) Derives du propenone
FI943119A (fi) Heterosyklisellä renkaalla substituoituja bentsyyliamiinijohdannaisia retrovirusvastaisina yhdisteinä
FI913893A0 (fi) Tricykliska heterocykliska derivat.
FI940607A0 (fi) Imidatso(5,1-C)(1,4)bentsoksatsin-1-onijohdannaiset 5HT3-antagonisteina
NO932258D0 (no) Heterocykliske, skadedyrdrepende forbindelser
DK325784A (da) Cytosinderivater, som er histamin h2-antagonister
FI935937A (fi) Mellanprodukt foer framstaellning av som laekemedel anvaendbara derivat av1h-imidazo(1,2-b)pyrazol

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee