DE69125569D1 - 8-Azabicyclo[3.2.1]octylalkylthiazolidinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel - Google Patents

8-Azabicyclo[3.2.1]octylalkylthiazolidinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Info

Publication number
DE69125569D1
DE69125569D1 DE69125569T DE69125569T DE69125569D1 DE 69125569 D1 DE69125569 D1 DE 69125569D1 DE 69125569 T DE69125569 T DE 69125569T DE 69125569 T DE69125569 T DE 69125569T DE 69125569 D1 DE69125569 D1 DE 69125569D1
Authority
DE
Germany
Prior art keywords
octylalkylthiazolidinones
azabicyclo
medicines
preparation
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69125569T
Other languages
English (en)
Other versions
DE69125569T2 (de
Inventor
Nicholas J Hrib
John G Jurcak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DE69125569D1 publication Critical patent/DE69125569D1/de
Publication of DE69125569T2 publication Critical patent/DE69125569T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69125569T 1990-10-26 1991-10-21 8-Azabicyclo[3.2.1]octylalkylthiazolidinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel Expired - Fee Related DE69125569T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/603,491 US5045546A (en) 1990-10-26 1990-10-26 8-azabicyclo[3.2.1]octylalkylthiazolidines

Publications (2)

Publication Number Publication Date
DE69125569D1 true DE69125569D1 (de) 1997-05-15
DE69125569T2 DE69125569T2 (de) 1997-09-18

Family

ID=24415671

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125569T Expired - Fee Related DE69125569T2 (de) 1990-10-26 1991-10-21 8-Azabicyclo[3.2.1]octylalkylthiazolidinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Country Status (19)

Country Link
US (1) US5045546A (de)
EP (1) EP0483633B1 (de)
JP (1) JP2564719B2 (de)
AT (1) ATE151422T1 (de)
AU (1) AU639195B2 (de)
BR (1) BR9104632A (de)
CA (1) CA2054225A1 (de)
CS (1) CS323091A3 (de)
DE (1) DE69125569T2 (de)
DK (1) DK0483633T3 (de)
ES (1) ES2099727T3 (de)
FI (1) FI915025A (de)
GR (1) GR3023441T3 (de)
HU (1) HUT59401A (de)
IE (1) IE913756A1 (de)
NO (1) NO914192L (de)
PT (1) PT99331B (de)
YU (1) YU168491A (de)
ZA (1) ZA918518B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE70363T1 (de) 1986-02-20 1991-12-15 Raychem Corp Einen ionentauschenden stoff verwendende verfahren und gegenstand.
US5801186A (en) * 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
CA2157348A1 (en) * 1994-09-01 1996-03-02 Aventis Pharmaceuticals Inc. 3-¬4-(1-substituted-4-piperazinyl)butyl|-4-thiazolidinone and related compounds
KR100589872B1 (ko) 1997-05-30 2006-06-15 뉴로서치 에이/에스 8-아자비사이클로(3,2,1)옥트-2-엔 유도체 및 이의 제조방법
KR100812499B1 (ko) * 2006-10-16 2008-03-11 이도훈 항경련제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2804460A (en) * 1955-07-15 1957-08-27 Irwin Neisler And Company Tropene derivatives
US3452029A (en) * 1966-11-21 1969-06-24 American Home Prod 3-alpha-phenylbenzyloxy - 8 - substituted nortropanes and their substitutents
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
EP0316723B1 (de) * 1987-11-20 1992-09-30 Hoechst-Roussel Pharmaceuticals Incorporated 3-[4(1-Substituierte-4-Piperazinyl)butyl]-4-Thiazolidinone, Verfahren zu deren Herstellung und ihre Anwendung als Arzneimittel

Also Published As

Publication number Publication date
YU168491A (sh) 1995-01-31
ES2099727T3 (es) 1997-06-01
PT99331A (pt) 1992-09-30
DE69125569T2 (de) 1997-09-18
ZA918518B (en) 1992-07-29
JP2564719B2 (ja) 1996-12-18
AU8606291A (en) 1992-04-30
AU639195B2 (en) 1993-07-15
FI915025A (fi) 1992-04-27
CA2054225A1 (en) 1992-04-27
CS323091A3 (en) 1992-05-13
US5045546A (en) 1991-09-03
HU913370D0 (en) 1992-01-28
FI915025A0 (fi) 1991-10-24
ATE151422T1 (de) 1997-04-15
NO914192D0 (no) 1991-10-25
EP0483633B1 (de) 1997-04-09
PT99331B (pt) 2000-08-31
DK0483633T3 (da) 1997-09-15
BR9104632A (pt) 1992-06-09
IE913756A1 (en) 1992-05-22
EP0483633A1 (de) 1992-05-06
GR3023441T3 (en) 1997-08-29
HUT59401A (en) 1992-05-28
NO914192L (no) 1992-04-27
JPH04264085A (ja) 1992-09-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee