DE69119700T2 - Verwendung von Xanthinen zur Herstellung von Arzneimitteln zur Hemmung der Vermehrung menschlicher Retroviren - Google Patents

Verwendung von Xanthinen zur Herstellung von Arzneimitteln zur Hemmung der Vermehrung menschlicher Retroviren

Info

Publication number
DE69119700T2
DE69119700T2 DE69119700T DE69119700T DE69119700T2 DE 69119700 T2 DE69119700 T2 DE 69119700T2 DE 69119700 T DE69119700 T DE 69119700T DE 69119700 T DE69119700 T DE 69119700T DE 69119700 T2 DE69119700 T2 DE 69119700T2
Authority
DE
Germany
Prior art keywords
group
chem
formula
carbon atoms
stands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69119700T
Other languages
English (en)
Other versions
DE69119700D1 (de
Inventor
Bruce J Dezube
Arthur B Pardee
Ruth M Ruprecht
William J Novick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of DE69119700D1 publication Critical patent/DE69119700D1/de
Application granted granted Critical
Publication of DE69119700T2 publication Critical patent/DE69119700T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
DE69119700T 1990-11-07 1991-10-28 Verwendung von Xanthinen zur Herstellung von Arzneimitteln zur Hemmung der Vermehrung menschlicher Retroviren Expired - Fee Related DE69119700T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61023090A 1990-11-07 1990-11-07

Publications (2)

Publication Number Publication Date
DE69119700D1 DE69119700D1 (de) 1996-06-27
DE69119700T2 true DE69119700T2 (de) 1996-11-07

Family

ID=24444220

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69119700T Expired - Fee Related DE69119700T2 (de) 1990-11-07 1991-10-28 Verwendung von Xanthinen zur Herstellung von Arzneimitteln zur Hemmung der Vermehrung menschlicher Retroviren

Country Status (16)

Country Link
EP (1) EP0484785B1 (de)
JP (1) JPH054922A (de)
KR (1) KR920009397A (de)
AT (1) ATE138266T1 (de)
AU (1) AU649278B2 (de)
CA (1) CA2055041A1 (de)
DE (1) DE69119700T2 (de)
DK (1) DK0484785T3 (de)
ES (1) ES2087205T3 (de)
GR (1) GR3020017T3 (de)
HU (1) HUT61468A (de)
IE (1) IE913879A1 (de)
IL (1) IL99966A0 (de)
PT (1) PT99434A (de)
TW (1) TW209169B (de)
ZA (1) ZA918801B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0557876T3 (da) * 1992-02-22 1997-05-26 Hoechst Ag Anvendelse af xanthinderivater til behandling af muskelskader efter fuldstændig afbrydelse af blodcirkulationen
ES2275400B1 (es) * 2005-04-20 2008-04-01 Universidad Autonoma De Madrid Uso de compuestos agonistas de la actividad tubulina desacetilasa de la proteina hdac6 en la elaboracion de composiciones farmaceuticas, dichas composiciones farmaceuticas y sus aplicaciones en el tratamiento de infecciones virales.
JP5567503B2 (ja) 2008-02-29 2014-08-06 コンサート ファーマシューティカルズ インコーポレイテッド 置換キサンチン誘導体
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8952016B2 (en) 2009-02-27 2015-02-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EP2611807A2 (de) 2010-09-01 2013-07-10 Concert Pharmaceuticals Inc. Polymorphe aus (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purin-2,6(3h,7h)dion
US20140296263A1 (en) 2011-07-19 2014-10-02 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
CN104364255A (zh) 2012-04-13 2015-02-18 康塞特医药品有限公司 取代的黄嘌呤衍生物
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3737433A (en) * 1964-09-05 1973-06-05 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines
CH608236A5 (de) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4663317A (en) * 1984-04-18 1987-05-05 Board Of Regents, University Of Texas System Methods and compositions for treating viral infections
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
GB8610136D0 (en) * 1986-04-25 1986-05-29 Wellcome Found Compounds
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung

Also Published As

Publication number Publication date
DK0484785T3 (da) 1996-09-23
DE69119700D1 (de) 1996-06-27
AU8699891A (en) 1992-05-14
JPH054922A (ja) 1993-01-14
PT99434A (pt) 1992-09-30
AU649278B2 (en) 1994-05-19
HUT61468A (en) 1993-01-28
ATE138266T1 (de) 1996-06-15
IL99966A0 (en) 1992-08-18
KR920009397A (ko) 1992-06-25
EP0484785A3 (en) 1992-12-16
EP0484785B1 (de) 1996-05-22
ZA918801B (en) 1992-12-30
HU913502D0 (en) 1992-01-28
TW209169B (de) 1993-07-11
ES2087205T3 (es) 1996-07-16
CA2055041A1 (en) 1992-05-08
EP0484785A2 (de) 1992-05-13
IE913879A1 (en) 1992-05-20
GR3020017T3 (en) 1996-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee