DE69113811T2 - COMPOSITION FOR LOCAL APPLICATION. - Google Patents

COMPOSITION FOR LOCAL APPLICATION.

Info

Publication number
DE69113811T2
DE69113811T2 DE69113811T DE69113811T DE69113811T2 DE 69113811 T2 DE69113811 T2 DE 69113811T2 DE 69113811 T DE69113811 T DE 69113811T DE 69113811 T DE69113811 T DE 69113811T DE 69113811 T2 DE69113811 T2 DE 69113811T2
Authority
DE
Germany
Prior art keywords
composition
local application
liquid phases
application
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69113811T
Other languages
German (de)
Other versions
DE69113811D1 (en
Inventor
Adrian Davis
Jennifer Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE69113811D1 publication Critical patent/DE69113811D1/en
Publication of DE69113811T2 publication Critical patent/DE69113811T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Two-component pharmaceutical compositions for topical application to the human or animal body and intended for mixing together on or immediately prior to application, comprising two liquid phases having different lipophilicities and a drug dissolved in at least one of the liquid phases.
DE69113811T 1990-11-27 1991-11-21 COMPOSITION FOR LOCAL APPLICATION. Expired - Lifetime DE69113811T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909025711A GB9025711D0 (en) 1990-11-27 1990-11-27 Topical composition
PCT/GB1991/002064 WO1992009266A1 (en) 1990-11-27 1991-11-21 Topical composition

Publications (2)

Publication Number Publication Date
DE69113811D1 DE69113811D1 (en) 1995-11-16
DE69113811T2 true DE69113811T2 (en) 1996-04-11

Family

ID=10686018

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113811T Expired - Lifetime DE69113811T2 (en) 1990-11-27 1991-11-21 COMPOSITION FOR LOCAL APPLICATION.

Country Status (19)

Country Link
EP (1) EP0559682B1 (en)
JP (1) JPH06502856A (en)
KR (1) KR100218652B1 (en)
AT (1) ATE128862T1 (en)
AU (1) AU661283B2 (en)
CA (1) CA2096963C (en)
DE (1) DE69113811T2 (en)
DK (1) DK0559682T3 (en)
ES (1) ES2079687T3 (en)
GB (1) GB9025711D0 (en)
GR (1) GR3018613T3 (en)
HK (1) HK1006279A1 (en)
IE (1) IE68953B1 (en)
MY (1) MY108692A (en)
NZ (1) NZ240707A (en)
PT (1) PT99608B (en)
SA (1) SA92120308B1 (en)
WO (1) WO1992009266A1 (en)
ZA (1) ZA919289B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9125712D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Skin care composition
GB9207988D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Topical composition
US5464610A (en) * 1992-10-15 1995-11-07 Schering-Plough Healthcare Products, Inc. Method for treating onychomycosis
US5484606A (en) * 1994-01-24 1996-01-16 The Procter & Gamble Company Process for reducing the precipitation of difficulty soluble pharmaceutical actives
US6019988A (en) * 1996-11-18 2000-02-01 Bristol-Myers Squibb Company Methods and compositions for enhancing skin permeation of drugs using permeation enhancers, when drugs and/or permeation enhancers are unstable in combination during long-term storage
FR2771634B1 (en) * 1997-12-02 2000-04-28 Jean Pierre Benoit HAIR AND / OR BODY HYGIENE PRODUCT FOR MEN AND ANIMALS AND METHOD FOR THE PRODUCTION THEREOF
US6649174B2 (en) 1998-05-07 2003-11-18 E-L Management Corp. Dual phase cosmetic composition
US6524623B1 (en) * 1999-11-12 2003-02-25 Milton Hodosh Therapeutic compositions and methods of use thereof
DE10235422A1 (en) * 2002-08-02 2004-02-12 Beiersdorf Ag Two-phase cosmetic or dermatological composition comprises an aqueous phase containing an alcohol and one or more alkali(ne earth) metal salts and a lipid phase with a defined interfacial tension

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8319540D0 (en) * 1983-07-20 1983-08-24 Bovril Ltd Amine removal
GB8629639D0 (en) * 1986-12-11 1987-01-21 Beecham Group Plc Composition & method
GB8401965D0 (en) * 1984-01-25 1984-02-29 Beecham Group Plc Composition

Also Published As

Publication number Publication date
KR930702958A (en) 1993-11-29
HK1006279A1 (en) 1999-02-19
DK0559682T3 (en) 1995-12-04
ATE128862T1 (en) 1995-10-15
SA92120308B1 (en) 2005-06-15
CA2096963A1 (en) 1992-05-28
MY108692A (en) 1996-10-31
NZ240707A (en) 1994-02-25
KR100218652B1 (en) 1999-09-01
IE914090A1 (en) 1992-06-03
AU661283B2 (en) 1995-07-20
PT99608A (en) 1992-11-30
ES2079687T3 (en) 1996-01-16
GR3018613T3 (en) 1996-04-30
EP0559682A1 (en) 1993-09-15
WO1992009266A1 (en) 1992-06-11
JPH06502856A (en) 1994-03-31
AU8929591A (en) 1992-06-25
DE69113811D1 (en) 1995-11-16
ZA919289B (en) 1992-10-28
GB9025711D0 (en) 1991-01-09
PT99608B (en) 1999-05-31
EP0559682B1 (en) 1995-10-11
IE68953B1 (en) 1996-07-24
CA2096963C (en) 2002-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition