DE69024999D1 - Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden - Google Patents

Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden

Info

Publication number
DE69024999D1
DE69024999D1 DE69024999T DE69024999T DE69024999D1 DE 69024999 D1 DE69024999 D1 DE 69024999D1 DE 69024999 T DE69024999 T DE 69024999T DE 69024999 T DE69024999 T DE 69024999T DE 69024999 D1 DE69024999 D1 DE 69024999D1
Authority
DE
Germany
Prior art keywords
oxindole
carboxamides
preparation
agents
trichloracetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69024999T
Other languages
English (en)
Other versions
DE69024999T2 (de
Inventor
Sarah Elizabeth Kelly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69024999D1 publication Critical patent/DE69024999D1/de
Publication of DE69024999T2 publication Critical patent/DE69024999T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69024999T 1989-05-25 1990-05-21 Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden Expired - Fee Related DE69024999T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/357,138 US4952703A (en) 1989-05-25 1989-05-25 Intermediates for making 2-oxindole-1-carboxamides

Publications (2)

Publication Number Publication Date
DE69024999D1 true DE69024999D1 (de) 1996-03-07
DE69024999T2 DE69024999T2 (de) 1996-05-30

Family

ID=23404454

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024999T Expired - Fee Related DE69024999T2 (de) 1989-05-25 1990-05-21 Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden

Country Status (12)

Country Link
US (1) US4952703A (de)
EP (1) EP0399748B1 (de)
JP (2) JPH07119211B2 (de)
AT (1) ATE133409T1 (de)
CA (1) CA2017328A1 (de)
DE (1) DE69024999T2 (de)
DK (1) DK0399748T3 (de)
ES (1) ES2083427T3 (de)
FI (1) FI902590A0 (de)
GR (1) GR3019276T3 (de)
IE (1) IE70066B1 (de)
PT (1) PT94127B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086186A (en) * 1989-05-25 1992-02-04 Pfizer Inc. N-trichloroacetyl-2-oxindole-1-carboxamides
CA2155664C (en) * 1993-02-09 1999-06-15 Ralph P. Robinson Oxindole 1-[n-(alkoxycarbonyl)]carboxamides and 1-(n-carboxamido)carboxamides as antiinflammatory agents
US5449788A (en) * 1994-01-28 1995-09-12 Catalytica, Inc. Process for preparing 2-oxindole-1-carboxamides
JP4201840B2 (ja) * 1996-12-18 2008-12-24 明治製菓株式会社 新規テトラヒドロベンズインドロン誘導体
CN103242304A (zh) * 2013-05-21 2013-08-14 苏州科捷生物医药有限公司 消炎药替尼达普钠的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471119A (en) * 1981-10-10 1984-09-11 Fisons Plc Certain hydrolysis or reductive cleavage reaction involving 4h-pyrano(3,2-g) quinoline-2,8-dicarboxylic acid derivatives
IN163263B (de) * 1984-02-07 1988-08-27 Pfizer
EP0155828B1 (de) * 1984-03-19 1990-09-19 Pfizer Inc. Verfahren zur Herstellung von 2-oxindole-1-Carboxamiden und deren Zwischenprodukte
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4665194A (en) * 1984-12-21 1987-05-12 Pfizer Inc. Process for making 2-oxindole-1-carboxamides and intermediates therefor
EP0303418A3 (de) * 1987-08-11 1990-11-07 Smithkline Beecham Laboratoires Pharmaceutiques Substituierte Indolone, verwendbar in der Behandlung von Herz- oder Asthmakrankheiten

Also Published As

Publication number Publication date
ES2083427T3 (es) 1996-04-16
FI902590A0 (fi) 1990-05-24
DE69024999T2 (de) 1996-05-30
JPH07215935A (ja) 1995-08-15
GR3019276T3 (en) 1996-06-30
EP0399748A2 (de) 1990-11-28
EP0399748B1 (de) 1996-01-24
EP0399748A3 (de) 1992-01-08
ATE133409T1 (de) 1996-02-15
JPH07119211B2 (ja) 1995-12-20
PT94127A (pt) 1991-01-08
CA2017328A1 (en) 1990-11-25
DK0399748T3 (da) 1996-02-12
IE901871L (en) 1990-11-25
JP2500853B2 (ja) 1996-05-29
JPH0311061A (ja) 1991-01-18
PT94127B (pt) 1997-01-31
US4952703A (en) 1990-08-28
IE70066B1 (en) 1996-10-30

Similar Documents

Publication Publication Date Title
DE3580803D1 (de) Neue zwischenprodukte und verfahren zur herstellung von 3-acylamino-1-hydroxy-2-azetidinonen.
ATE415394T1 (de) Zwischeprodukte zur herstellung von retroviralen protease-hemmern
DE69016590T2 (de) Verfahren zur Herstellung von Acrylsäure.
DE69011880T2 (de) Verfahren zur Herstellung von L-Aminosäuren durch Fermentation.
DE69221745D1 (de) Verfahren zur kombinierten Herstellung von organischen Zusammenstellungen und Energie
DE3683883D1 (de) Verfahren zur herstellung von organopolysilanen und verwendung der so hergestellten organopolysilane.
DE69231815T2 (de) Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
ATE64154T1 (de) Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
DE69024999D1 (de) Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden
ATE4458T1 (de) Verfahren zur herstellung von 1,4:3,6-dianhydro-d-glucit-5-nitrat (isosorbid-5-nitrat).
DE59010027D1 (de) Verfahren zur diskontinuierlichen Herstellung von L-Carnitin auf mikrobiologischem Weg
DE59104516D1 (de) Verfahren zur herstellung von aminomethanphosphonsäure und aminomethyl-phosphinsäuren.
DE69032153D1 (de) Verfahren zur Herstellung von Butantetracarboxylat
ATE92056T1 (de) Verfahren zur herstellung von 5-chlor-3chlorsulfonyl-2-thiophencarbonsaeureestern.
DE69308934T2 (de) Verfahren zur Herstellung von 1,1,1,2-Tetrafluorethan
DE69332707T2 (de) Verfahren zur Herstellung von 3-Vinylcephalosporinen
ATE43342T1 (de) Verfahren zur herstellung von hydrogeno- oder halogenosilanen.
ATE56704T1 (de) Verfahren zur herstellung von 2-oxindole-1carboxamiden und deren zwischenprodukte.
ATE200776T1 (de) Verfahren zur herstellung von 2,4,5-tribrompyrrol-3-carbonitril
DE3584528D1 (de) Katalytisches verfahren zur herstellung von amiden.
ATE100789T1 (de) Verfahren zur herstellung von saeureanhydriden.
ATE98953T1 (de) Verfahren und zwischenprodukte zur herstellung von isopropylestern von 3s-amino-2rhydroxyalkans|uren.
ATE10623T1 (de) Verfahren zur herstellung von l-prolin.
DE69116198T2 (de) Verfahren zur Herstellung von D-Isocitronensäure durch Fermentation
ATE27281T1 (de) Verfahren zur herstellung von oxanosin.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee