DE69020002D1 - Ribonukleotidreduktase-Hemmer. - Google Patents
Ribonukleotidreduktase-Hemmer.Info
- Publication number
- DE69020002D1 DE69020002D1 DE69020002T DE69020002T DE69020002D1 DE 69020002 D1 DE69020002 D1 DE 69020002D1 DE 69020002 T DE69020002 T DE 69020002T DE 69020002 T DE69020002 T DE 69020002T DE 69020002 D1 DE69020002 D1 DE 69020002D1
- Authority
- DE
- Germany
- Prior art keywords
- amino
- phe
- decapeptide
- tyr
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA000591372A CA1327869C (en) | 1989-02-17 | 1989-02-17 | Ribonucleotide reductase inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69020002D1 true DE69020002D1 (de) | 1995-07-20 |
DE69020002T2 DE69020002T2 (de) | 1995-12-14 |
Family
ID=4139636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69020002T Expired - Fee Related DE69020002T2 (de) | 1989-02-17 | 1990-02-08 | Ribonukleotidreduktase-Hemmer. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5071835A (de) |
EP (1) | EP0383190B1 (de) |
JP (1) | JPH02264796A (de) |
AT (1) | ATE123783T1 (de) |
AU (1) | AU633543B2 (de) |
CA (1) | CA1327869C (de) |
DE (1) | DE69020002T2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU643636B2 (en) * | 1989-07-07 | 1993-11-18 | Bio-Mega/Boehringer Ingelheim Research Inc. | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain |
EP0411333B1 (de) * | 1989-07-07 | 1995-05-31 | Bio-Mega/Boehringer Ingelheim Research Inc. | Antiherpes-Tetrapeptid-Derivate mit einer substituierten Seitenkette aus Asparaginsäure |
WO1992013549A1 (en) * | 1991-02-07 | 1992-08-20 | Research Corporation Technologies, Inc. | Inhibition of cell proliferation by hydrophobic peptides |
US5459063A (en) * | 1993-10-14 | 1995-10-17 | The University Of Pennsylvania | Plasmodium falciparum ribonucleotide reductase DNA |
WO1998000532A2 (en) * | 1996-07-01 | 1998-01-08 | Wright Jim A | Oligonucleotides from the untranslated regions of ribonucleotide reductase and their use to modulate cell growth |
US6593305B1 (en) | 1996-08-02 | 2003-07-15 | Genesense Technologies Inc. | Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase |
AU2004209579B2 (en) | 2003-02-10 | 2010-03-04 | Lorus Therapeutics Inc. | Antisense oligonucleotides directed to ribonucleotide reductase R2 and uses thereof in the treatment of cancer |
US8029815B2 (en) * | 2004-04-28 | 2011-10-04 | Elford Howard L | Methods for treating or preventing restenosis and other vascular proliferative disorders |
ZA200609927B (en) * | 2004-05-28 | 2008-07-30 | Unigen Pharmaceuticals Inc | Diarylalkanes as potent inhibitors of binuclear enzymes |
EP2030615A3 (de) * | 2007-08-13 | 2009-12-02 | ELFORD, Howard L. | Ribonukleotidreduktase-Inhibitoren zur Verwendung für die Behandlung oder Vorbeugung von Nervenentzündung- oder Autoimmunerkrankungen |
KR101988329B1 (ko) | 2008-07-21 | 2019-06-12 | 유니젠, 인크. | 일련의 피부-화이트닝(라이트닝) 화합물 |
CA2830993C (en) | 2011-03-24 | 2019-07-02 | Unigen, Inc. | Compounds and methods for preparation of diarylpropanes |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4448730A (en) * | 1981-03-24 | 1984-05-15 | Riet Bartholomeus Van T | Hydroxybenzohydroxamic acids, benzamides and esters and related compounds as ribonucleotide reductase inhibitors |
US4795740A (en) * | 1986-05-20 | 1989-01-03 | Cohen Eric A | Antiviral peptides and means for treating herpes infections |
US4814432A (en) * | 1987-05-22 | 1989-03-21 | Merck & Co., Inc. | Inhibitor of ribonucleotide reductase |
US4845195A (en) * | 1987-05-22 | 1989-07-04 | Merck & Co., Inc. | Inhibitor of ribonucleotide reductase |
US4837304A (en) * | 1987-05-22 | 1989-06-06 | Merck & Co., Inc. | Inhibitor of ribonucleotide reductase |
-
1989
- 1989-02-17 CA CA000591372A patent/CA1327869C/en not_active Expired - Fee Related
-
1990
- 1990-02-01 US US07/474,589 patent/US5071835A/en not_active Expired - Lifetime
- 1990-02-08 DE DE69020002T patent/DE69020002T2/de not_active Expired - Fee Related
- 1990-02-08 EP EP90102453A patent/EP0383190B1/de not_active Expired - Lifetime
- 1990-02-08 AT AT90102453T patent/ATE123783T1/de active
- 1990-02-16 JP JP2035987A patent/JPH02264796A/ja active Pending
- 1990-02-16 AU AU49867/90A patent/AU633543B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0383190A3 (de) | 1991-11-21 |
US5071835A (en) | 1991-12-10 |
AU633543B2 (en) | 1993-02-04 |
EP0383190A2 (de) | 1990-08-22 |
AU4986790A (en) | 1990-08-23 |
JPH02264796A (ja) | 1990-10-29 |
CA1327869C (en) | 1994-03-15 |
EP0383190B1 (de) | 1995-06-14 |
DE69020002T2 (de) | 1995-12-14 |
ATE123783T1 (de) | 1995-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |