DE69008653D1 - Verfahren zur Racemisierung von optisch aktiven 4-Phenylbuttersäureestern. - Google Patents

Verfahren zur Racemisierung von optisch aktiven 4-Phenylbuttersäureestern.

Info

Publication number
DE69008653D1
DE69008653D1 DE69008653T DE69008653T DE69008653D1 DE 69008653 D1 DE69008653 D1 DE 69008653D1 DE 69008653 T DE69008653 T DE 69008653T DE 69008653 T DE69008653 T DE 69008653T DE 69008653 D1 DE69008653 D1 DE 69008653D1
Authority
DE
Germany
Prior art keywords
acid esters
optically active
racemization
alkali metal
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69008653T
Other languages
English (en)
Other versions
DE69008653T2 (de
Inventor
Hiroyuki Nohira
Takashi Onishi
Kazuo Yamamoto
Noriaki Kumagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Publication of DE69008653D1 publication Critical patent/DE69008653D1/de
Application granted granted Critical
Publication of DE69008653T2 publication Critical patent/DE69008653T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00Racemisation; Complete or partial inversion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69008653T 1989-10-06 1990-10-05 Verfahren zur Racemisierung von optisch aktiven 4-Phenylbuttersäureestern. Expired - Fee Related DE69008653T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26251689 1989-10-06

Publications (2)

Publication Number Publication Date
DE69008653D1 true DE69008653D1 (de) 1994-06-09
DE69008653T2 DE69008653T2 (de) 1994-12-01

Family

ID=17376891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69008653T Expired - Fee Related DE69008653T2 (de) 1989-10-06 1990-10-05 Verfahren zur Racemisierung von optisch aktiven 4-Phenylbuttersäureestern.

Country Status (6)

Country Link
US (1) US5066826A (de)
EP (1) EP0421472B1 (de)
JP (1) JP2507163B2 (de)
AT (1) ATE105277T1 (de)
DE (1) DE69008653T2 (de)
ES (1) ES2056331T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202457A (en) * 1990-04-12 1993-04-13 Chisso Corporation Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof
DE69213916T2 (de) * 1991-12-29 1997-03-06 Kuraray Co Verfahren zur Herstellung von L-Ambrox
JPH06116217A (ja) * 1992-10-02 1994-04-26 Kuraray Co Ltd (±)−シス−4−アミノシクロペント−2−エンカルボン酸誘導体の光学分割法
US6342636B1 (en) * 1997-11-06 2002-01-29 Yamakawa Chemical Industry Co., Ltd. Process for preparing optically active amines and optically active carboxylic acids, and intermediates for preparation
CN101412672B (zh) * 2008-11-18 2012-05-23 浙江大学 R-2-羟基-4-苯基丁酸乙酯的化学合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3621835A1 (de) * 1986-06-28 1988-01-07 Hoechst Ag Verfahren zur racemisierung optisch aktiver (alpha)-phenoxypropionsaeure und deren derivate
US4837354A (en) * 1987-02-26 1989-06-06 Merrell Dow Pharmaceuticals Inc. Process for making and isolating (R)-2-hydroxy-4-phenylbutyric acid and esters
EP0325971A3 (de) * 1988-01-26 1990-07-25 F. Hoffmann-La Roche Ag Verfahren zur Herstellung optisch reiner Hydroxyarylalkansäuren und -ester
US4904822A (en) * 1988-02-19 1990-02-27 Kuraray Co., Ltd. Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid
JPH0216954A (ja) * 1988-07-05 1990-01-19 Muronoki Shokuhin Kk 魚卵を主成分とするシート食品及びその製造方法
JPH0247100A (ja) * 1988-08-09 1990-02-16 Murata Kinpaku:Kk 転写箔を部分的に転写する方法
JP2817145B2 (ja) * 1988-09-17 1998-10-27 カシオ計算機株式会社 エンベロープ発生装置

Also Published As

Publication number Publication date
JP2507163B2 (ja) 1996-06-12
EP0421472B1 (de) 1994-05-04
ES2056331T3 (es) 1994-10-01
US5066826A (en) 1991-11-19
DE69008653T2 (de) 1994-12-01
ATE105277T1 (de) 1994-05-15
EP0421472A1 (de) 1991-04-10
JPH03204838A (ja) 1991-09-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee