DE69008535D1 - Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden. - Google Patents

Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden.

Info

Publication number
DE69008535D1
DE69008535D1 DE69008535T DE69008535T DE69008535D1 DE 69008535 D1 DE69008535 D1 DE 69008535D1 DE 69008535 T DE69008535 T DE 69008535T DE 69008535 T DE69008535 T DE 69008535T DE 69008535 D1 DE69008535 D1 DE 69008535D1
Authority
DE
Germany
Prior art keywords
antigamma
humane
clarified
detected
synthetic peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69008535T
Other languages
English (en)
Other versions
DE69008535T2 (de
Inventor
Adolfo Turano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69008535D1 publication Critical patent/DE69008535D1/de
Application granted granted Critical
Publication of DE69008535T2 publication Critical patent/DE69008535T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69008535T 1989-08-11 1990-08-08 Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden. Expired - Fee Related DE69008535T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8921517A IT1231727B (it) 1989-08-11 1989-08-11 Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.
PCT/EP1990/001293 WO1991002005A1 (en) 1989-08-11 1990-08-08 Natural human anti-gamma interferon antibodies detected and purified by synthetic peptides

Publications (2)

Publication Number Publication Date
DE69008535D1 true DE69008535D1 (de) 1994-06-01
DE69008535T2 DE69008535T2 (de) 1994-12-15

Family

ID=11182983

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69008535T Expired - Fee Related DE69008535T2 (de) 1989-08-11 1990-08-08 Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden.

Country Status (6)

Country Link
EP (1) EP0485471B1 (de)
JP (1) JPH05500360A (de)
AU (1) AU6176690A (de)
DE (1) DE69008535T2 (de)
IT (1) IT1231727B (de)
WO (1) WO1991002005A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
ZA917669B (en) * 1990-09-27 1992-08-26 Schering Corp Antagonists of human gamma interferon
US5888511A (en) * 1993-02-26 1999-03-30 Advanced Biotherapy Concepts, Inc. Treatment of autoimmune diseases, including AIDS
DK96493D0 (da) * 1993-08-26 1993-08-26 Mouritsen Og Elsner Aps Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
GB2304342A (en) * 1995-08-18 1997-03-19 Univ Manchester Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma
US20020025316A1 (en) 1995-08-18 2002-02-28 Ferguson Mark Williams James Pharmaceutical composition containing inhibitors of interferon-gamma
ES2251248T3 (es) 1998-12-09 2006-04-16 Protein Design Labs, Inc. Uso de anticuerpos contra il-12 para tratar la psoriasis.
US7084257B2 (en) 2001-10-05 2006-08-01 Amgen Inc. Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
AU2003285874A1 (en) * 2002-10-16 2004-05-04 Amgen Inc. HUMAN ANTI-IFN-Gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-Gamma PATHWAY INHIBITORS
CA2502668C (en) * 2002-10-17 2013-07-30 Amgen Inc. Fully human antibody fab fragments with human interferon-gamma neutralizing activity
CN115176157A (zh) * 2020-06-29 2022-10-11 玛希隆大学 用于检测抗干扰素γ抗体的免疫层析方法及试剂盒
CN116769026A (zh) * 2023-05-11 2023-09-19 广州医科大学附属第一医院 一种抗IFN-γ自身抗体的纯化工艺及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681848A (en) * 1982-09-22 1987-07-21 Takeda Chemical Industries, Ltd. Novel peptide and use thereof
US4599306A (en) * 1983-04-15 1986-07-08 Amgen Monoclonal antibodies which specifically bind to human immune interferon
US4473555A (en) * 1983-10-17 1984-09-25 Syntex (U.S.A.) Inc. Nona- and dodecapeptides for augmenting natural killer cell activity
DE3426077A1 (de) * 1984-07-14 1986-01-23 Dr. Karl Thomae Gmbh, 7950 Biberach Monoklonale antikoerper gegen humanes ifn-(gamma), diese antikoerper produzierende hybridzellinien, verwendung der neuen antikoerper und verfahren zu deren herstellung
NL8700927A (nl) * 1987-04-16 1988-11-16 Stichting Rega V Z W Anti-interferon-gamma-antilichamen; en hun therapeutische toepassing.
CA1335792C (en) * 1987-08-18 1995-06-06 Chaim O. Jacob Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease

Also Published As

Publication number Publication date
IT1231727B (it) 1991-12-21
IT8921517A0 (it) 1989-08-11
WO1991002005A1 (en) 1991-02-21
AU6176690A (en) 1991-03-11
JPH05500360A (ja) 1993-01-28
EP0485471B1 (de) 1994-04-27
EP0485471A1 (de) 1992-05-20
DE69008535T2 (de) 1994-12-15

Similar Documents

Publication Publication Date Title
DE68914835D1 (de) Proteinerzeugnisse.
DE69430060D1 (de) Antikörper von rapamycinen mit offenem ring
DE68914698D1 (de) Modifikation der Pharmakokinetika von Proteinen durch Ladungsänderung.
DE68903482D1 (de) Zement, verfahren zur herstellung dieses zements und verfahren zur herstellung von produkten mit diesem zement.
DE68903576D1 (de) Signalpeptide, die in hefe wirksam sind und ihre verwendung zur sekretorischen expression von heterologen proteinen.
DE68904679D1 (de) Elektroplattierung von kleinen partikeln.
DE69008535D1 (de) Humane antigammainterferonantikörper, welche detektiert und geklärt sind mit verwendung von synthetischen peptiden.
NO892294D0 (no) Polypeptidforbindelser.
DE3788807D1 (de) Fusionsproteine und -partikel.
DE69000466D1 (de) Steuern von teilchenmaterial.
DE69106562D1 (de) Oberfläche mit verringerter Proteinwechselwirkung.
DE3788852D1 (de) Proteine mit Glutathion-S-Transferase-Aktivität, DNA-Sequenzen, Antikörper, Poxviren und Arzneimittel zur Prävention von Schistosomiasis.
DE58907026D1 (de) Alkoxymethyl- und Alkenyloxymethyl-cyclohexane.
IL98769A0 (en) Synthetic peptides,mixtures thereof and methods utilizing the same for detecting hiv antibodies
ATE111292T1 (de) Heizen von lagern und dergleichen.
FI904357A0 (fi) Foerfarande foer aktivering av protein c.
DE58900581D1 (de) Halter zur fixierung von zumindest einem laenglichen rundkoerper.
ZA918423B (en) Proteins and nucleic acids.
CA2199403A1 (en) Novel PKA-Binding Proteins and Uses Thereof
NO892948D0 (no) Modifiserte proteiner.
ATE104990T1 (de) Humane antigammainterferonantikoerper, welche detektiert und geklaert sind mit verwendung von synthetischen peptiden.
FI892254A0 (fi) Anvaendning av a-aminoboronsyraderivat foer stabilisering av peptid- och proteinlaekemedel.
CA2199843A1 (en) Novel PKA-Binding Proteins and Uses Thereof
DE58905961D1 (de) Ultrazentrifuge zur Bestimmung von Teilchengrössenverteilungen.
DE68908004D1 (de) Verwendung von karbon-materialien.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee