DE68927097D1 - Differentieller refraktometer - Google Patents

Differentieller refraktometer

Info

Publication number
DE68927097D1
DE68927097D1 DE68927097T DE68927097T DE68927097D1 DE 68927097 D1 DE68927097 D1 DE 68927097D1 DE 68927097 T DE68927097 T DE 68927097T DE 68927097 T DE68927097 T DE 68927097T DE 68927097 D1 DE68927097 D1 DE 68927097D1
Authority
DE
Germany
Prior art keywords
differential refractometer
refractometer
differential
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927097T
Other languages
English (en)
Other versions
DE68927097T2 (de
Inventor
Philip Wyatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyatt Technology LLC
Original Assignee
Wyatt Technology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyatt Technology LLC filed Critical Wyatt Technology LLC
Application granted granted Critical
Publication of DE68927097D1 publication Critical patent/DE68927097D1/de
Publication of DE68927097T2 publication Critical patent/DE68927097T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/4133—Refractometers, e.g. differential
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE68927097T 1988-10-03 1989-05-25 Differentieller refraktometer Expired - Fee Related DE68927097T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/252,331 US4952055A (en) 1988-10-03 1988-10-03 Differential refractometer
PCT/US1989/002255 WO1990004165A1 (en) 1988-10-03 1989-05-25 Differential refractometer

Publications (2)

Publication Number Publication Date
DE68927097D1 true DE68927097D1 (de) 1996-10-10
DE68927097T2 DE68927097T2 (de) 1997-01-16

Family

ID=22955577

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927097T Expired - Fee Related DE68927097T2 (de) 1988-10-03 1989-05-25 Differentieller refraktometer

Country Status (5)

Country Link
US (2) US4952055A (de)
EP (1) EP0389571B1 (de)
JP (1) JPH03501773A (de)
DE (1) DE68927097T2 (de)
WO (1) WO1990004165A1 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952055A (en) * 1988-10-03 1990-08-28 Wyatt Technology Corporation Differential refractometer
US5350697A (en) * 1990-08-28 1994-09-27 Akzo N.V. Scattered light detection apparatus
US5223142A (en) * 1991-01-11 1993-06-29 Biotage Inc. Production chromatography process using a critical angle refractive index detector
US5139661A (en) * 1991-01-11 1992-08-18 Biotage Inc. Critical angle refractive index detector
DE9206066U1 (de) * 1992-05-05 1993-09-02 Vermögensverwaltungs-Kommanditgesellschaft Dr. Ing. Herbert Knauer & Co. GmbH & Cie., 14163 Berlin Laserbrechungsindexdetektor
SE500817C2 (sv) * 1993-01-27 1994-09-12 Anders Hanning Sätt att bestämma koncentrationen av en analyt i ett vätskekromatografiskt eller kapillärelektroforetiskt flöde genom att mäta vätskans brytningsindex
US5422714A (en) * 1993-06-07 1995-06-06 Corning Incorporated Device for comparing the refractive indices of an optical immersion liquid and a reference glass
US5701176A (en) * 1995-07-28 1997-12-23 Precision Detectors, Inc. High temperature light scattering measurement device comprising a rigid extension tube
US6356675B1 (en) * 1995-12-01 2002-03-12 Sandia Corporation Fiber optic refractive index monitor
US5676830A (en) * 1996-04-12 1997-10-14 Wyatt Technology Corporation Method and apparatus for reducing band broadening in chromatographic detectors
US5870185A (en) * 1996-10-21 1999-02-09 C.F.C. Technology, Inc. Apparatus and method for fluid analysis
US6087182A (en) * 1998-08-27 2000-07-11 Abbott Laboratories Reagentless analysis of biological samples
EP1115430A4 (de) * 1998-10-01 2002-01-02 Minntech Corp System zur nachbehandlung und zum sterilisieren von endoskopen
US6549276B1 (en) * 1998-10-30 2003-04-15 Research Foundation Of State University Of New York Method and apparatus for optical measurement of concentration and temperature of liquids
US6942989B2 (en) 1999-05-03 2005-09-13 Icf Technologies, Inc. Methods, compositions and kits for biological indicator of sterilization
US20040106167A1 (en) * 1999-05-03 2004-06-03 Icf Technologies, Inc. Methods for evaluating sterilization procedures using a biological indicator
US7326562B2 (en) * 1999-05-03 2008-02-05 Icf Technologies, Inc. Biological indicator system to detect effectiveness of sterilization
US6381025B1 (en) 1999-08-19 2002-04-30 Texas Tech University Interferometric detection system and method
US6687004B1 (en) * 1999-10-22 2004-02-03 Marquette University Optical sensor for opaque and non-opaque materials
GB2371358A (en) * 2001-01-22 2002-07-24 Optokem Ltd Light scattering particle characterisation apparatus and detection means
US6809828B2 (en) 2001-01-25 2004-10-26 Texas Tech University Universal detector for biological and chemical separations or assays using plastic microfluidic devices
US6519033B1 (en) 2001-11-19 2003-02-11 Point Source Technologies, Llc Identification of particles in fluid
US6774995B2 (en) * 2001-08-03 2004-08-10 Pointsource Technologies, Llc Identification of particles in fluid
DE10141544A1 (de) * 2001-08-24 2003-03-13 Eppendorf Ag Vorrichtung zur Behandlung von Flüssigkeiten und Verfahren zum Betreiben der Vorrichtung
US6573992B1 (en) 2001-11-13 2003-06-03 Pointsource Technologies, Llc Plano convex fluid carrier for scattering correction
US6590652B2 (en) 2001-11-02 2003-07-08 Pointsource Technologies, Inc. Flow through light scattering device
US6628386B2 (en) 2001-12-12 2003-09-30 Pointsource Technologies, Llc Particle detection beam
US6717663B2 (en) 2002-03-08 2004-04-06 Reichert, Inc. Optical configuration and method for differential refractive index measurements
US6930769B1 (en) 2002-03-21 2005-08-16 Pointsource Technologies, Llc Optical sensor module tester
US7057724B1 (en) 2002-03-21 2006-06-06 Institute Of Critical Care Medicine Particulate info to field units
US6683681B2 (en) * 2002-04-10 2004-01-27 Baker Hughes Incorporated Method and apparatus for a downhole refractometer and attenuated reflectance spectrometer
US7016026B2 (en) 2002-04-10 2006-03-21 Baker Hughes Incorporated Method and apparatus for a downhole refractometer and attenuated reflectance spectrometer
US6972424B1 (en) 2002-04-16 2005-12-06 Pointsource Technologies, Llc High detection rate particle identifier
US6819421B1 (en) 2003-04-11 2004-11-16 Point Source Technologies, Llc Detection of new species of particles
US7105849B2 (en) * 2003-05-20 2006-09-12 Technology Innovations, Llc Hydrocarbon fluid analysis module
US6774994B1 (en) * 2003-08-13 2004-08-10 Wyatt Technology Corporation Method and apparatus for determining absolute number densities of particles in suspension
US7386427B2 (en) * 2003-09-18 2008-06-10 Wyatt Technology Corporation Method for correcting the effects of interdetector band broadening
US20050151968A1 (en) * 2004-01-08 2005-07-14 The Lxt Group Systems and methods for continuous, on-line, real-time surveillance of particles in a fluid
US6975392B2 (en) * 2004-01-29 2005-12-13 Wyatt Technology Corporation Enhanced sensitivity differential refractometer measurement cell
US7027138B2 (en) * 2004-01-29 2006-04-11 Wyatt Technology Corporation Enhanced sensitivity differential refractometer incorporating a photodetector array
US7283220B2 (en) * 2004-03-24 2007-10-16 Fujitsu Limited Methods and apparatuses for measuring the refractive index and other optical properties of liquids, gels, and solids
GB0415882D0 (en) * 2004-07-15 2004-08-18 Univ Southampton Optical sensors
GB0417337D0 (en) * 2004-08-04 2004-09-08 Chu Andrew C Low cost air bubble detector and alarm system for fluid administrative applications
WO2006100414A1 (en) * 2005-03-24 2006-09-28 Sheffield Hallam University Method and apparatus for particle analysis
US7630076B2 (en) * 2005-07-26 2009-12-08 University Of Connecticut Dual-detector systems and methods having utility in biomolecular measurements
DE102006013263A1 (de) * 2006-03-21 2007-09-27 Daimlerchrysler Ag Verfahren zur Bestimmung einer Konzentration eines Bestandteils einer Flüssigkeit in einem Kraftfahrzeug
TW200742847A (en) * 2006-05-15 2007-11-16 Syspotek Corp Refractive fuel-concentration detecto
WO2009019619A1 (en) * 2007-08-09 2009-02-12 Koninklijke Philips Electronics N. V. Microelectronic sensor device for optical examinations in a sample medium
WO2009039466A1 (en) 2007-09-20 2009-03-26 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
US7982875B2 (en) * 2009-06-15 2011-07-19 Wyatt Technology Corporation Method and apparatus for measuring the scattered light signals from a liquid sample
US8867027B2 (en) 2010-06-03 2014-10-21 Koninklijke Philips N.V. Apparatus and method for estimating bilirubin concentration using refractometry
WO2011156713A1 (en) 2010-06-11 2011-12-15 Vanderbilt University Multiplexed interferometric detection system and method
US8542353B2 (en) 2010-09-30 2013-09-24 Precision Energy Services, Inc. Refractive index sensor for fluid analysis
US8411262B2 (en) 2010-09-30 2013-04-02 Precision Energy Services, Inc. Downhole gas breakout sensor
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
US9146192B2 (en) * 2012-05-17 2015-09-29 Wyatt Technology Corporation Integrated light scattering and ultraviolet absorption measurement system
US8817258B2 (en) 2012-05-21 2014-08-26 Common Sensing Inc. Dose measurement system and method
US9255830B2 (en) 2012-05-21 2016-02-09 Common Sensing Inc. Dose measurement system and method
JP2014032098A (ja) * 2012-08-03 2014-02-20 Hitachi High-Technologies Corp 液体クロマトグラフ分析装置
GB2558835B (en) 2013-03-15 2018-11-21 Waters Technologies Corp Systems and devices for refractive index detection
EP3152983A1 (de) * 2014-06-06 2017-04-12 TRUMPF Lasersystems for Semiconductor Manufacturing GmbH Vorrichtung und verfahren zur überwachung eines laserstrahls
WO2016019375A1 (en) 2014-08-01 2016-02-04 Common Sensing Inc. Liquid measurement systems, apparatus, and methods optimized with temperature sensing
JP2018506715A (ja) 2015-01-23 2018-03-08 ヴァンダービルト ユニバーシティー 堅固なインターフェロメーター及びその使用方法
US10408716B2 (en) 2015-09-22 2019-09-10 Wyatt Technology Corporation Method and apparatus to measure multiple signals from a liquid sample
US10627396B2 (en) 2016-01-29 2020-04-21 Vanderbilt University Free-solution response function interferometry
WO2017212718A1 (ja) * 2016-06-10 2017-12-14 ソニー株式会社 微小粒子測定装置及び微小粒子測定装置の洗浄方法
CA3029651A1 (en) 2016-07-15 2018-01-18 Common Sensing Inc. Dose measurement systems and methods
US10901228B2 (en) * 2017-06-27 2021-01-26 The Boeing Company Cavity with curved beam replicator and method of determining a characteristic of a medium therein
JP6954360B2 (ja) * 2017-09-14 2021-10-27 株式会社島津製作所 屈折率測定装置および屈折率測定装置用セル
US10466173B2 (en) * 2017-10-06 2019-11-05 Wyatt Technology Corporation Optical flow cell assembly incorporating a replaceable transparent flow cell
EP3599455B1 (de) * 2018-07-27 2022-03-23 Heraeus Quarzglas GmbH & Co. KG Vorrichtung und verfahren zur analyse von partikeln
US11953476B2 (en) 2018-10-18 2024-04-09 Polymer Characterization, S.A. Deflection-type refractometer with extended measurement range
US10458909B1 (en) 2018-10-24 2019-10-29 International Business Machines Corporation MEMS optical sensor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075426A (en) * 1958-07-21 1963-01-29 Cons Electrodynamics Corp Refractometry apparatus
US3386332A (en) * 1964-07-13 1968-06-04 Emmett S. Watson Differential refractometry
US3636360A (en) * 1968-05-13 1972-01-18 Hitachi Ltd Apparatus for detection of liquid level in transparent tube comprising photocell located to receive light which has been totally reflected
US3619068A (en) * 1969-08-28 1971-11-09 Phillips Petroleum Co Refractometer
SE438208B (sv) * 1978-04-17 1985-04-01 Sten Silverbage Metcell for anvendning i en refraktometer
US4448691A (en) * 1980-09-02 1984-05-15 The Dow Chemical Company Liquid chromatographic method and apparatus with hollow fiber device for post-column derivatization
DE3414261A1 (de) * 1984-04-14 1985-10-24 Fa. Carl Zeiss, 7920 Heidenheim Interferenz-refraktometer
US4616927A (en) * 1984-11-15 1986-10-14 Wyatt Technology Corporation Sample cell for light scattering measurements
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US4710643A (en) * 1986-08-08 1987-12-01 Marine Moisture Control Company, Inc. Method and apparatus for determining the degree of purity of a liquid
US4952055A (en) * 1988-10-03 1990-08-28 Wyatt Technology Corporation Differential refractometer

Also Published As

Publication number Publication date
EP0389571A4 (en) 1991-01-23
EP0389571A1 (de) 1990-10-03
DE68927097T2 (de) 1997-01-16
US4952055A (en) 1990-08-28
EP0389571B1 (de) 1996-09-04
US5305071A (en) 1994-04-19
WO1990004165A1 (en) 1990-04-19
JPH03501773A (ja) 1991-04-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee