DE68921923D1 - Rekombinante Coccidiosis-Vakzine. - Google Patents

Rekombinante Coccidiosis-Vakzine.

Info

Publication number
DE68921923D1
DE68921923D1 DE68921923T DE68921923T DE68921923D1 DE 68921923 D1 DE68921923 D1 DE 68921923D1 DE 68921923 T DE68921923 T DE 68921923T DE 68921923 T DE68921923 T DE 68921923T DE 68921923 D1 DE68921923 D1 DE 68921923D1
Authority
DE
Germany
Prior art keywords
coccidiosis vaccine
recombinant
recombinant coccidiosis
vaccine
coccidiosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68921923T
Other languages
English (en)
Other versions
DE68921923T2 (de
Inventor
Werner Altenburger
Mary-Helen Binger
Richard Anthony Chizzonite
Richard Allen Kramer
Peter Thomas Lomedico
Stephen J Mcandrew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpharma Luxembourg SARL
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE68921923D1 publication Critical patent/DE68921923D1/de
Publication of DE68921923T2 publication Critical patent/DE68921923T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455Eimeria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE68921923T 1988-06-03 1989-06-02 Rekombinante Coccidiosis-Vakzine. Expired - Fee Related DE68921923T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20272188A 1988-06-03 1988-06-03

Publications (2)

Publication Number Publication Date
DE68921923D1 true DE68921923D1 (de) 1995-05-04
DE68921923T2 DE68921923T2 (de) 1995-08-10

Family

ID=22750986

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68921923T Expired - Fee Related DE68921923T2 (de) 1988-06-03 1989-06-02 Rekombinante Coccidiosis-Vakzine.

Country Status (22)

Country Link
US (2) US5661015A (de)
EP (1) EP0344808B1 (de)
JP (1) JP3051130B2 (de)
KR (1) KR0156545B1 (de)
CN (3) CN1040126C (de)
AR (1) AR241942A1 (de)
AT (1) ATE120489T1 (de)
AU (1) AU635704B2 (de)
CA (1) CA1340538C (de)
DE (1) DE68921923T2 (de)
DK (1) DK272889A (de)
ES (1) ES2070866T3 (de)
FI (1) FI101453B1 (de)
HU (1) HU212505B (de)
IE (1) IE67544B1 (de)
IL (1) IL90489A0 (de)
MC (1) MC2039A1 (de)
NO (1) NO303876B1 (de)
NZ (1) NZ229377A (de)
PT (1) PT90727B (de)
YU (1) YU47880B (de)
ZA (1) ZA893740B (de)

Families Citing this family (33)

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Publication number Priority date Publication date Assignee Title
US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
JPH03505970A (ja) * 1988-07-05 1991-12-26 ジェネックス・コーポレーション 遺伝子工学によるコクシジウム症ワクチン
ZA902147B (en) * 1989-03-28 1990-12-28 Akzo Nv Coccidiosis vaccine
ATE94208T1 (de) * 1989-06-21 1993-09-15 Akzo Nv Eimeria tenella-vakzin.
ZA9010461B (en) * 1990-01-26 1991-10-30 Hoffmann La Roche Recombinant coccidiosis vaccines-5-7 eimeria surface antigen
WO1992016627A1 (en) * 1991-03-14 1992-10-01 British Technology Group Usa, Inc. Recombinant anticoccidial vaccine
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
MX9709870A (es) 1995-06-07 1998-03-31 Pfizer Uso de esporocistos u occistos para preparar una vacuna contra coccidiosis.
US6500438B2 (en) 1995-06-07 2002-12-31 Pfizer Incorporated In ovo vaccination against coccidiosis
ES2253746T3 (es) 1995-07-03 2006-06-01 Akzo Nobel N.V. Vacuna contra la coccidiosis aviar.
US5891692A (en) * 1996-03-29 1999-04-06 Life Technologies, Inc. Method for increasing the viability and transformation ability of bacteria during or after storage at low temperatures
US6632923B1 (en) * 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US6627205B2 (en) 1997-12-01 2003-09-30 Pfizer Incorporated Ovo vaccination against coccidiosis
US6984378B1 (en) 1999-02-26 2006-01-10 Pfizer, Inc. Method for the purification, recovery, and sporulation of cysts and oocysts
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
KR100490669B1 (ko) * 2001-08-30 2005-05-19 (주)아비코아생명공학연구소 조류 콕시듐증을 유발하는 에이메리아 종의 포자소체 표면항원에 대한 scFv 재조합 항체
CN103316371A (zh) 2001-08-30 2013-09-25 恩布里克斯公司 制备卵囊的改进方法
JP3995541B2 (ja) * 2002-06-28 2007-10-24 株式会社ゲン・コーポレーション 抗鶏コクシジウム症組成物
DE10330235A1 (de) * 2003-07-04 2005-01-20 Bayer Healthcare Ag Neues Eimeria Gen und Protein sowie deren Verwendung
EP1667702A2 (de) * 2003-09-10 2006-06-14 Baxter International Inc., Baxter Healthcare Corp. Peptide zur hemmung der komplement-aktivierung
ATE471155T1 (de) * 2004-03-12 2010-07-15 Univ Georgia Neues impfstoffadjuvans und dessen herstellung und verwendung
US7087425B2 (en) * 2004-03-31 2006-08-08 Embrex, Inc. Method of purifying oocysts using enzymatic digestion of fecal debris
US20110078828A1 (en) * 2004-09-10 2011-03-31 Guardian Biotechnologies Inc. Multi epitope vaccine for poultry
DE602005003429T2 (de) * 2004-12-01 2008-10-02 Zeon Corp. Kodierende DNS für ein Eimeria Apical Membran Antigen 1 und dessen Verwendungen
CN100398156C (zh) * 2005-11-23 2008-07-02 南京农业大学 用于预防鸡球虫病的免疫调节型dna疫苗
US20080194006A1 (en) * 2007-02-08 2008-08-14 Embrex, Inc. Methods of releasing sporocysts from oocysts using controlled shear forces
US11701683B2 (en) 2010-12-22 2023-07-18 The Procter & Gamble Company Methods for foil stamping parts having asymmetrical edges
EP3558350A1 (de) 2016-12-22 2019-10-30 Intervet International B.V. Eimeria-impfstoff mit verbesserter wirksamkeit
WO2020243240A1 (en) * 2019-05-28 2020-12-03 Case Western Reserve University Compositions and methods for preserving dna methylation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
DE2814039C3 (de) 1978-03-31 1981-02-19 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Herstellung von Hybrid-Bakterien
US4710377A (en) * 1983-08-19 1987-12-01 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of Eimeria spp.
US4650676A (en) 1983-08-19 1987-03-17 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozoites of Eimeria spp.
EP0135073A3 (de) * 1983-08-19 1987-05-27 American Cyanamid Company Gegen Merozoiten von Eimeria Spp. reaktive monoklonale Antikörper und Antigene
EP0135712A3 (de) * 1983-08-19 1987-05-27 American Cyanamid Company Gegen Sporozoiten von Eimeria Spp. reaktive monoklonale Antikörper und Antigene
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US5187080A (en) * 1984-06-05 1993-02-16 Solvay & Cie S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US4874705A (en) * 1985-05-16 1989-10-17 Solvay & Cie, S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US4639372A (en) 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
WO1986000528A1 (en) * 1984-07-05 1986-01-30 Genex Corporation Cloned gene and method for making and using the same
ATE73494T1 (de) * 1985-12-03 1992-03-15 Solvay Antigene proteine und diese enthaltende impfstoffe zur verhuetung von kokzidiose.
EP0241139A3 (de) * 1986-03-13 1989-04-19 Merck & Co. Inc. Antiidiotypischer Coccidiaimpfstoff
US5496550A (en) * 1986-08-14 1996-03-05 Chilwalner Method of reducing the output of Eimeria oocysts from a newborn chick
EP0614973A1 (de) * 1987-03-06 1994-09-14 Amgen Boulder Inc. Für die Diagnose von Coccidia-Infektion verwendbares Polypeptid, sowie gentechnologisches Verfahren zu dessen Herstellung
EP0315073A2 (de) * 1987-11-02 1989-05-10 Matsushita Electric Industrial Co., Ltd. Zusammensetzung für Bilderzeugung
NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
NZ227595A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Recombinant production of eimeria tenella antigens and their use
AU620366B2 (en) * 1988-02-12 1992-02-20 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated response and method of producing the same
DE3926461A1 (de) * 1989-07-15 1991-01-24 Suttner Gmbh & Co Kg Ventilpistole, insbesondere fuer ein hochdruckreinigungsgeraet

Also Published As

Publication number Publication date
IE891812L (en) 1989-12-03
ATE120489T1 (de) 1995-04-15
DE68921923T2 (de) 1995-08-10
YU47880B (sh) 1996-05-20
EP0344808A1 (de) 1989-12-06
NO892251L (no) 1989-12-04
AU635704B2 (en) 1993-04-01
PT90727B (pt) 1994-11-30
CN1038837A (zh) 1990-01-17
KR0156545B1 (ko) 1998-11-16
CA1340538C (en) 1999-05-11
DK272889A (da) 1989-12-04
KR910000183A (ko) 1991-01-29
ZA893740B (en) 1990-02-28
HUT52963A (en) 1990-09-28
CN1077438C (zh) 2002-01-09
MC2039A1 (fr) 1990-05-30
EP0344808B1 (de) 1995-03-29
NO303876B1 (no) 1998-09-14
AU3601689A (en) 1989-12-07
FI101453B (fi) 1998-06-30
HU212505B (en) 1996-07-29
AR241942A1 (es) 1993-01-29
FI101453B1 (fi) 1998-06-30
NZ229377A (en) 1992-06-25
FI892714A (fi) 1989-12-04
JPH037594A (ja) 1991-01-14
CN1076204C (zh) 2001-12-19
YU113889A (en) 1991-10-31
CN1186695A (zh) 1998-07-08
CN1040126C (zh) 1998-10-07
IE67544B1 (en) 1996-04-17
DK272889D0 (da) 1989-06-02
NO892251D0 (no) 1989-06-02
IL90489A0 (en) 1990-01-18
ES2070866T3 (es) 1995-06-16
FI892714A0 (fi) 1989-06-02
PT90727A (pt) 1989-12-29
US20030175311A1 (en) 2003-09-18
US5661015A (en) 1997-08-26
JP3051130B2 (ja) 2000-06-12
CN1187368A (zh) 1998-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ALPHARMA (LUXEMBOURG) S.A.R.L., LUXEMBURG/LUXEMBOU

8339 Ceased/non-payment of the annual fee