DE68919887D1 - Verfahren zur Herstellung von 1-alpha,25-dihydroxy-vitamin D2 und dessen 24-Epimer. - Google Patents

Verfahren zur Herstellung von 1-alpha,25-dihydroxy-vitamin D2 und dessen 24-Epimer.

Info

Publication number
DE68919887D1
DE68919887D1 DE68919887T DE68919887T DE68919887D1 DE 68919887 D1 DE68919887 D1 DE 68919887D1 DE 68919887 T DE68919887 T DE 68919887T DE 68919887 T DE68919887 T DE 68919887T DE 68919887 D1 DE68919887 D1 DE 68919887D1
Authority
DE
Germany
Prior art keywords
epimer
dihydroxy
vitamin
alpha
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68919887T
Other languages
English (en)
Other versions
DE68919887T2 (de
Inventor
Masahiro Tsuji
Shinji Yokoyama
Yoji Tachibana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Application granted granted Critical
Publication of DE68919887D1 publication Critical patent/DE68919887D1/de
Publication of DE68919887T2 publication Critical patent/DE68919887T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE68919887T 1988-04-11 1989-04-07 Verfahren zur Herstellung von 1-alpha,25-dihydroxy-vitamin D2 und dessen 24-Epimer. Expired - Fee Related DE68919887T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8726988 1988-04-11
JP63329178A JP2608322B2 (ja) 1988-04-11 1988-12-28 １α，２５‐ジヒドロキシビタミンＤ▲下２▼類の製造法

Publications (2)

Publication Number Publication Date
DE68919887D1 true DE68919887D1 (de) 1995-01-26
DE68919887T2 DE68919887T2 (de) 1995-04-27

Family

ID=26428559

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68919887T Expired - Fee Related DE68919887T2 (de) 1988-04-11 1989-04-07 Verfahren zur Herstellung von 1-alpha,25-dihydroxy-vitamin D2 und dessen 24-Epimer.

Country Status (5)

Country Link
US (1) US5087709A (de)
EP (1) EP0337305B1 (de)
JP (1) JP2608322B2 (de)
KR (1) KR970007949B1 (de)
DE (1) DE68919887T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
IN171449B (de) * 1990-02-14 1992-10-17 Wisconsin Alumni Res Found
JP3358812B2 (ja) * 1992-04-15 2002-12-24 エス・アール・アイ・インターナシヨナル ステロール混合物からの５，７ジエン官能基含有ステロイドの単離
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
US20090233889A1 (en) * 2008-03-12 2009-09-17 Uttam Saha Stabilized 1,25-dihydroxyvitamin d2 and method of making same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028484B1 (de) * 1979-10-23 1985-08-14 Teijin Limited Verfahren zur Herstellung aktiver Vitamin D3-Verbindungen und von Cholesta-5,7-dien-Vorläufern und so erhaltene Produkte
IE58277B1 (en) * 1983-05-09 1993-08-25 Wisconsin Alumni Res Found 1 , 25-dihydroxylated vitamin d2 compounds and intermediates in the preparation thereof
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity

Also Published As

Publication number Publication date
EP0337305A1 (de) 1989-10-18
KR970007949B1 (ko) 1997-05-19
JPH0236166A (ja) 1990-02-06
DE68919887T2 (de) 1995-04-27
EP0337305B1 (de) 1994-12-14
US5087709A (en) 1992-02-11
KR900016250A (ko) 1990-11-13
JP2608322B2 (ja) 1997-05-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NISSHIN SEIFUN GROUP INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee