DE68902946D1 - Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number
DE68902946D1
DE68902946D1 DE8989401016T DE68902946T DE68902946D1 DE 68902946 D1 DE68902946 D1 DE 68902946D1 DE 8989401016 T DE8989401016 T DE 8989401016T DE 68902946 T DE68902946 T DE 68902946T DE 68902946 D1 DE68902946 D1 DE 68902946D1
Authority
DE
Germany
Prior art keywords
group
aminocarbonyl
lower alkyl
alkyloxy
heteroarotinoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989401016T
Other languages
English (en)
Other versions
DE68902946T2 (de
Inventor
Jean Daniel Brion
Baut Guillaume Le
Patrick Ducrey
Sylvie Piessard-Robert
Claude Cudennec
Genevieve Seurre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE68902946D1 publication Critical patent/DE68902946D1/de
Application granted granted Critical
Publication of DE68902946T2 publication Critical patent/DE68902946T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE8989401016T 1988-04-13 1989-04-13 Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. Expired - Fee Related DE68902946T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8804870A FR2630110B1 (fr) 1988-04-13 1988-04-13 Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE68902946D1 true DE68902946D1 (de) 1992-10-29
DE68902946T2 DE68902946T2 (de) 1993-04-29

Family

ID=9365267

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989401016T Expired - Fee Related DE68902946T2 (de) 1988-04-13 1989-04-13 Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (16)

Country Link
US (1) US4975455A (de)
EP (1) EP0338895B1 (de)
JP (1) JPH01305078A (de)
AT (1) ATE80881T1 (de)
AU (1) AU610379B2 (de)
CA (1) CA1326674C (de)
DE (1) DE68902946T2 (de)
DK (1) DK179289A (de)
ES (1) ES2035598T3 (de)
FR (1) FR2630110B1 (de)
GR (1) GR3006480T3 (de)
IE (1) IE64357B1 (de)
NZ (1) NZ228716A (de)
OA (1) OA09114A (de)
PT (1) PT90261B (de)
ZA (1) ZA892716B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH0852659A (ja) * 1994-08-08 1996-02-27 Tousetsu Denki Kk バイス
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651034A5 (de) * 1982-05-12 1985-08-30 Hoffmann La Roche Chroman-, thiochroman- oder 1,2,3,4-tetrahydrochinolinderivate und ihre verwendung als arzneimittel-wirkstoffe.
US4808597A (en) * 1983-07-05 1989-02-28 Pfizer Inc. Method for inhibiting the degradation of cartilage
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤
US4826984A (en) * 1984-04-09 1989-05-02 The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University Heteroarotinoid compounds as anticancer agents
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
JPH0585550B2 (de) 1993-12-07
DK179289D0 (da) 1989-04-13
NZ228716A (en) 1990-11-27
AU610379B2 (en) 1991-05-16
ES2035598T3 (es) 1993-04-16
US4975455A (en) 1990-12-04
PT90261B (pt) 1994-07-29
PT90261A (pt) 1989-11-10
CA1326674C (fr) 1994-02-01
AU3265989A (en) 1989-12-21
FR2630110B1 (fr) 1990-07-27
IE891161L (en) 1989-10-13
FR2630110A1 (fr) 1989-10-20
ZA892716B (en) 1989-12-27
ATE80881T1 (de) 1992-10-15
IE64357B1 (en) 1995-07-26
OA09114A (fr) 1991-10-31
DK179289A (da) 1989-10-14
EP0338895A1 (de) 1989-10-25
EP0338895B1 (de) 1992-09-23
GR3006480T3 (de) 1993-06-21
DE68902946T2 (de) 1993-04-29
JPH01305078A (ja) 1989-12-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee