DE655307C - Drug capsule - Google Patents

Drug capsule

Info

Publication number
DE655307C
DE655307C DESCH110903D DESC110903D DE655307C DE 655307 C DE655307 C DE 655307C DE SCH110903 D DESCH110903 D DE SCH110903D DE SC110903 D DESC110903 D DE SC110903D DE 655307 C DE655307 C DE 655307C
Authority
DE
Germany
Prior art keywords
tragacanth
capsule
urea
drug capsule
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DESCH110903D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DESCH110903D priority Critical patent/DE655307C/en
Application granted granted Critical
Publication of DE655307C publication Critical patent/DE655307C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Description

Arzneikapsel Die nach dem Hauptpatent hergestellten Arzneikapseln sind in der Körperhöhle, in welche- sie mit dem Heilmittel verbracht werden, unter der Einwirkung der Körperwärme und -feuchtigkeit leicht löslich. In vielen Anwendungsfällen ist jedoch eine geringere Löslichkeit des Heilmittelbehälters erwünscht, z. B. immer dann, wenn das Heilmittel auf das :erkrankte Organ längere Zeit einwirken soll.Medicinal capsule The medicinal capsules manufactured according to the main patent are in the body cavity into which they are placed with the remedy, under Easily soluble in the action of body heat and moisture. In many use cases however, a lower solubility of the medicament container is desired, e.g. B. always when the remedy is to act on the diseased organ for a longer period of time.

Um nun die Herstellung von hauptsächlich aus Harnstoff bestehenden Kapseln, die schwer löslich sind, zu ermöglichen, wird gemäß vorliegender Erfindung bei der Herstellung der Kapsel dem Harnstoff eine geringe Menge Tragant beigemengt. Tragant hat bekanntlich die Eigenschaft, unter Einwirkung von Feuchtigkeit zu quellen. Das Quellen wird im vorliegenden. Fall durch die Feuchtigkeit der Körperhöhle 'herbeigeführt. Infolge der Quellung des Tragantes wird die Auflösung der Kapsel verzögert.To now the production of mainly composed of urea Enabling capsules that are sparingly soluble is, according to the present invention A small amount of tragacanth was added to the urea during the manufacture of the capsule. It is well known that tragacanth has the property of swelling when exposed to moisture. The swelling is in the present. Fall brought about by the moisture of the body cavity '. As a result of the swelling of the tragacanth, the dissolution of the capsule is delayed.

Bei der Ausführung der Erfindung wird beispielsweise folgendermaßen verfahren: Einer breiförmigen Mischung von Tragant und Wasser. wird so viel trockenes Harnstoffpulver beigemengt, daß ein steifer Brei entsteht. Das Mengenverhältnis von Tragani zu Harnstoff ist etwa i :2o. Der Teig wird getrocknet, wobei die Masse sich zu einem harten Körper verfestigt. Dieser Körper wird nun trocken gemahlen. Das erzeugte Pulver wird mit Wasser angefeuchtet und in Formen gepreßt. Der Preßling wird getrocknet und stellt dann die fertige Kapsel dar.In practicing the invention, for example, the following is used Method: A pulpy mixture of tragacanth and water. becomes so much dry Urea powder added to make a stiff pulp. The quantity ratio from tragani to urea is about i: 2o. The dough is dried, with the mass solidified into a hard body. This body is now ground dry. The powder produced is moistened with water and pressed into molds. The compact is dried and then represents the finished capsule.

Claims (2)

PATENTANSPRÜCHE: i. Verfahren zur Herstellung vonArzneikapseln nach Patent 626 1q:6, dadurch gekennzeichnet, daß dem Harnstoff zur Herabsetzung der Löslichkeit der Kapsel Tragant zugesetzt wird, beispielsweise im Mengenverhältnis 20:1. PATENT CLAIMS: i. Process for the production of medicament capsules according to Patent 626 1q: 6, characterized in that the urea to reduce the Solubility of the capsule tragacanth is added, for example in the quantitative ratio 20: 1. 2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß in eine Mischung von Tragant und Wasser trockenes Harnstoffpulver eingemengt, das Gemenge getrocknet, gemahlen, angefeuchtet und verpreßt wird.2. The method according to claim 1, characterized in that in a mixture dry urea powder mixed with tragacanth and water, the mixture dried, is ground, moistened and pressed.
DESCH110903D 1936-09-13 1936-09-13 Drug capsule Expired DE655307C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DESCH110903D DE655307C (en) 1936-09-13 1936-09-13 Drug capsule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DESCH110903D DE655307C (en) 1936-09-13 1936-09-13 Drug capsule

Publications (1)

Publication Number Publication Date
DE655307C true DE655307C (en) 1938-01-13

Family

ID=7449253

Family Applications (1)

Application Number Title Priority Date Filing Date
DESCH110903D Expired DE655307C (en) 1936-09-13 1936-09-13 Drug capsule

Country Status (1)

Country Link
DE (1) DE655307C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2073288A2 (en) * 1969-12-26 1971-10-01 Midy Claude Ctre Rech

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2073288A2 (en) * 1969-12-26 1971-10-01 Midy Claude Ctre Rech

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