DE60336403D1 - Metabolische phänotypisierung - Google Patents

Metabolische phänotypisierung

Info

Publication number
DE60336403D1
DE60336403D1 DE60336403T DE60336403T DE60336403D1 DE 60336403 D1 DE60336403 D1 DE 60336403D1 DE 60336403 T DE60336403 T DE 60336403T DE 60336403 T DE60336403 T DE 60336403T DE 60336403 D1 DE60336403 D1 DE 60336403D1
Authority
DE
Germany
Prior art keywords
subjects
dosing
dose
post
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60336403T
Other languages
English (en)
Inventor
T A Clayton
J R Everett
J C Lindon
J K Nicholson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Pfizer Inc
Original Assignee
Pfizer Ltd
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0213786A external-priority patent/GB0213786D0/en
Priority claimed from GB0213895A external-priority patent/GB0213895D0/en
Application filed by Pfizer Ltd, Pfizer Inc filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DE60336403D1 publication Critical patent/DE60336403D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60336403T 2002-06-14 2003-06-16 Metabolische phänotypisierung Expired - Lifetime DE60336403D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0213786A GB0213786D0 (en) 2002-06-14 2002-06-14 Metabolic phenotyping
GB0213895A GB0213895D0 (en) 2002-06-17 2002-06-17 Metabolic phenotyping
PCT/IB2003/002309 WO2003107270A2 (en) 2002-06-14 2003-06-16 Metabolic phenotyping

Publications (1)

Publication Number Publication Date
DE60336403D1 true DE60336403D1 (de) 2011-04-28

Family

ID=29738094

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60336403T Expired - Lifetime DE60336403D1 (de) 2002-06-14 2003-06-16 Metabolische phänotypisierung

Country Status (15)

Country Link
US (2) US20050074745A1 (de)
EP (1) EP1540560B1 (de)
JP (1) JP4829496B2 (de)
KR (1) KR20050012281A (de)
AT (1) ATE502343T1 (de)
AU (1) AU2003232406A1 (de)
CA (1) CA2487836C (de)
DE (1) DE60336403D1 (de)
HK (1) HK1080167A1 (de)
HR (1) HRP20041174A2 (de)
IL (1) IL165329A0 (de)
IN (1) IN2004DN03762A (de)
NO (1) NO20045111L (de)
RU (1) RU2004136317A (de)
WO (1) WO2003107270A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050037515A1 (en) * 2001-04-23 2005-02-17 Nicholson Jeremy Kirk Methods for analysis of spectral data and their applications osteoporosis
US20050130321A1 (en) * 2001-04-23 2005-06-16 Nicholson Jeremy K. Methods for analysis of spectral data and their applications
JP2005500543A (ja) * 2001-08-13 2005-01-06 ビヨンド ジェノミクス， インコーポレイテッド 生物学的系をプロファイリングするための方法およびシステム
IL165329A0 (en) 2002-06-14 2006-01-15 Pfizer Metabolic phenotyping
WO2005020125A2 (en) * 2003-08-20 2005-03-03 Bg Medicine, Inc. Methods and systems for profiling biological systems
WO2007050940A2 (en) * 2005-10-27 2007-05-03 Brandon Horn Method for determining metabolic type
US7899625B2 (en) * 2006-07-27 2011-03-01 International Business Machines Corporation Method and system for robust classification strategy for cancer detection from mass spectrometry data
CA2666339A1 (en) * 2006-10-13 2008-05-29 Metabolon, Inc. Biomarkers related to metabolic age and methods using the same
US20080286774A1 (en) * 2007-05-16 2008-11-20 The Regents Of The University Of California Real-time individualized therapy evaluation
US20100273203A1 (en) * 2009-04-23 2010-10-28 Board Of Trustees Of The University Of Arkansas Methods and compositions for detecting metabolites
US8660823B2 (en) * 2009-04-26 2014-02-25 Lester F. Ludwig Nonlinear and lie algebra structural analysis system for enzyme cascades, metabolic signal transduction, signaling pathways, catalytic chemical reaction networks, and immunology
GB0912744D0 (en) 2009-07-22 2009-08-26 Imp Innovations Ltd Methods and uses
GB0912685D0 (en) 2009-07-22 2009-08-26 Imp Innovations Ltd Methods
US8410064B2 (en) * 2009-08-24 2013-04-02 The Board Of Trustees Of The University Of Arkansas Classical cannabinoid metabolites and methods of use thereof
US8883218B2 (en) * 2010-03-26 2014-11-11 The Board Of Trustees Of The University Of Arkansas Anti-cancer nanoparticle compositions and methods of use
GB201012297D0 (en) * 2010-07-22 2010-09-08 Ge Healthcare Uk Ltd A system and method for automated biological cell assay data analysis
WO2012018535A2 (en) * 2010-07-26 2012-02-09 Wellness Indicators, Inc. Wellness panel
US9095598B2 (en) 2010-12-28 2015-08-04 The Board Of Trustees Of The University Of Arkansas Stilbenoid derivatives and their uses
US9535144B2 (en) 2012-06-01 2017-01-03 Liposcience, Inc. NMR quantification of TMAO
US9470771B2 (en) 2012-06-08 2016-10-18 Liposcience, Inc. NMR measurements of NMR biomarker GlycA
US9361429B2 (en) 2012-06-08 2016-06-07 Liposcience, Inc. Multi-parameter diabetes risk evaluations
US9928345B2 (en) 2012-06-08 2018-03-27 Liposciences, Inc. Multiple-marker risk parameters predictive of conversion to diabetes
RU2533846C1 (ru) * 2013-05-13 2014-11-20 Сергей Леонидович Устьянцев Способ определения энтропии в организме человека или животного
CN104215623B (zh) * 2013-05-31 2018-09-25 欧普图斯(苏州)光学纳米科技有限公司 面向多行业检测的激光拉曼光谱智能化辨识方法及***
US9953417B2 (en) 2013-10-04 2018-04-24 The University Of Manchester Biomarker method
US9519823B2 (en) * 2013-10-04 2016-12-13 The University Of Manchester Biomarker method
CN107764848A (zh) * 2016-08-18 2018-03-06 中国科学院烟台海岸带研究所 一种基于代谢组学评价石斑鱼饲料利用的方法
CN108717876B (zh) * 2018-05-11 2022-05-20 大连诺道认知医学技术有限公司 一种基于指定药物构建给药数据库的方法及装置
CN108766587B (zh) * 2018-05-11 2022-05-03 北京诺道认知医学科技有限公司 一种基于指定药物构建给药数据库的方法及装置
CN108445112B (zh) * 2018-05-29 2021-03-16 云南中烟工业有限责任公司 一种烟叶烟气中4-(n-甲基-n-亚硝胺)-1-(3-吡啶基)-丁酮的检测方法
WO2020081326A1 (en) * 2018-10-15 2020-04-23 Olaris, Inc. Spectographic metabolite-signature for identifying a subject's susceptibility to drugs
JP2022550916A (ja) * 2019-10-10 2022-12-05 ジョージア テック リサーチ コーポレイション 深紫外線顕微鏡を用いた無標識の血液学的および組織病理学的分析
DK3809118T3 (da) * 2019-10-17 2023-09-18 Evonik Operations Gmbh Fremgangsmåde til at forudsige en egenskabsværdi af et materiale ved anvendelse af hovedkomponentanalyse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6658396B1 (en) * 1999-11-29 2003-12-02 Tang Sharon S Neural network drug dosage estimation
WO2002010746A2 (en) * 2000-07-28 2002-02-07 Lion Bioscience Ag Pharmacokinetic tool and method for predicting metabolism of a compound in a mammal
IL165329A0 (en) 2002-06-14 2006-01-15 Pfizer Metabolic phenotyping

Also Published As

Publication number Publication date
KR20050012281A (ko) 2005-01-31
IN2004DN03762A (de) 2010-01-08
AU2003232406A1 (en) 2003-12-31
JP2005534899A (ja) 2005-11-17
WO2003107270A3 (en) 2005-04-21
WO2003107270A2 (en) 2003-12-24
NO20045111L (no) 2005-01-12
US20090192721A1 (en) 2009-07-30
CA2487836A1 (en) 2003-12-24
RU2004136317A (ru) 2006-01-27
HRP20041174A2 (en) 2005-06-30
HK1080167A1 (zh) 2006-04-21
US20050074745A1 (en) 2005-04-07
CA2487836C (en) 2014-12-02
EP1540560A2 (de) 2005-06-15
US8577617B2 (en) 2013-11-05
EP1540560B1 (de) 2011-03-16
ATE502343T1 (de) 2011-04-15
IL165329A0 (en) 2006-01-15
JP4829496B2 (ja) 2011-12-07

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