DE60329615D1 - Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats - Google Patents
Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivatsInfo
- Publication number
- DE60329615D1 DE60329615D1 DE60329615T DE60329615T DE60329615D1 DE 60329615 D1 DE60329615 D1 DE 60329615D1 DE 60329615 T DE60329615 T DE 60329615T DE 60329615 T DE60329615 T DE 60329615T DE 60329615 D1 DE60329615 D1 DE 60329615D1
- Authority
- DE
- Germany
- Prior art keywords
- derivative
- formula
- pyridyl
- give
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002214098A JP4208512B2 (ja) | 2002-07-23 | 2002-07-23 | ５−（２’−ピリジル）−２−ピリドン誘導体の製造方法 |
| PCT/JP2003/009316 WO2004009553A1 (ja) | 2002-07-23 | 2003-07-23 | ５−（２’−ピリジル）−２−ピリドン誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60329615D1 true DE60329615D1 (de) | 2009-11-19 |
Family
ID=30767870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60329615T Expired - Lifetime DE60329615D1 (de) | 2002-07-23 | 2003-07-23 | Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7524967B2 (de) |
| EP (1) | EP1553086B1 (de) |
| JP (1) | JP4208512B2 (de) |
| KR (1) | KR101025528B1 (de) |
| CN (1) | CN100393702C (de) |
| AT (1) | ATE444952T1 (de) |
| AU (1) | AU2003252241B2 (de) |
| CA (1) | CA2493036C (de) |
| DE (1) | DE60329615D1 (de) |
| HK (1) | HK1077578B (de) |
| IL (1) | IL166451A (de) |
| MX (1) | MXPA05000944A (de) |
| WO (1) | WO2004009553A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY148809A (en) | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
| ATE511843T1 (de) * | 2005-04-04 | 2011-06-15 | Eisai R&D Man Co Ltd | Dihydropyridin-verbindungen für neurodegenerative erkrankungen und demenz |
| EP1919906B1 (de) | 2005-08-29 | 2011-10-12 | Vertex Pharmaceuticals Incorporated | 3,5-disubstituierte pyrid-2-one, die als hemmer der tec-familie von nicht-rezeptor tyrosin-kinasen nützlich sind |
| US7786120B2 (en) | 2005-08-29 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Pyridones useful as inhibitors of kinases |
| US7691885B2 (en) * | 2005-08-29 | 2010-04-06 | Vertex Pharmaceuticals Incorporated | Pyridones useful as inhibitors of kinases |
| JP4865337B2 (ja) * | 2006-01-24 | 2012-02-01 | 富士フイルムファインケミカルズ株式会社 | ２，３’−ビピリジル−６’−オンの製造方法 |
| US20100016603A1 (en) * | 2007-01-29 | 2010-01-21 | Fujifilm Finechemicals Co., Ltd. | Production process of 2,3'-bipyridyl-6'-one |
| US20100099714A1 (en) * | 2007-03-05 | 2010-04-22 | Eisai R&D Management Co., Ltd. | AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases |
| US20100130537A1 (en) * | 2007-04-26 | 2010-05-27 | Eisai R&D Management Co., Ltd | Cinnamide compounds for dementia |
| US8742127B2 (en) | 2007-12-21 | 2014-06-03 | Kuraray Co., Ltd. | Production method of 6-halogeno-3-arylpyridine derivative |
| ITMI20111952A1 (it) | 2011-10-27 | 2013-04-28 | Italiana Sint Spa | Procedimento per la prepazione di 2-metossi-5-(piridin-2-il)piridina, un intermedio del perampanel |
| WO2013102897A1 (en) | 2012-01-03 | 2013-07-11 | Mapi Pharma Ltd. | Polymorphs of perampanel |
| WO2015013520A1 (en) | 2013-07-25 | 2015-01-29 | IVAX International GmbH | Process for the preparation of perampanel |
| CN104725301A (zh) * | 2013-12-20 | 2015-06-24 | 北京蓝贝望生物医药科技股份有限公司 | 一种1,2-二氢吡啶-2-酮衍生物的制备方法 |
| EP3259262A4 (de) | 2015-02-17 | 2018-08-01 | Mapi Pharma Limited | Verfahren und zwischenprodukte zur herstellung von perampanel |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693611A (en) | 1996-02-01 | 1997-12-02 | Eli Lilly And Company | Cyclic peptide antifungal agents |
| DE19633746A1 (de) * | 1996-08-22 | 1998-02-26 | Basf Ag | Substituierte 2-Phenylpyridine |
| DE19636995A1 (de) * | 1996-09-12 | 1998-03-19 | Basf Ag | Verfahren zur Herstellung substituierter Phenylpyridine |
| JP4176201B2 (ja) * | 1998-09-02 | 2008-11-05 | 株式会社クラレ | ５−ハロゲノ−２−置換ピリジンの製造方法 |
| JP2003511452A (ja) * | 1999-10-11 | 2003-03-25 | ファイザー・インク | ホスホジエステラーゼ阻害剤としての５−（２−置換−５−ヘテロシクリルスルホニルピリド−３−イル）−ジヒドロピラゾロ［４，３−ｄ］ピリミジン−７−オン |
| US20020045613A1 (en) | 2000-04-27 | 2002-04-18 | Heinz Pauls | 1-aroyl-piperidinyl benzamidines |
| US6949571B2 (en) * | 2000-06-12 | 2005-09-27 | Eisai Co., Ltd. | 1,2-dihydropyridine compounds, process for preparation of the same and use thereof |
-
2002
- 2002-07-23 JP JP2002214098A patent/JP4208512B2/ja not_active Expired - Fee Related
-
2003
- 2003-07-23 WO PCT/JP2003/009316 patent/WO2004009553A1/ja active Application Filing
- 2003-07-23 CA CA2493036A patent/CA2493036C/en not_active Expired - Fee Related
- 2003-07-23 CN CNB038176904A patent/CN100393702C/zh not_active Expired - Fee Related
- 2003-07-23 AU AU2003252241A patent/AU2003252241B2/en not_active Ceased
- 2003-07-23 KR KR1020057001229A patent/KR101025528B1/ko not_active IP Right Cessation
- 2003-07-23 US US10/521,800 patent/US7524967B2/en not_active Expired - Fee Related
- 2003-07-23 EP EP03765356A patent/EP1553086B1/de not_active Expired - Lifetime
- 2003-07-23 AT AT03765356T patent/ATE444952T1/de not_active IP Right Cessation
- 2003-07-23 MX MXPA05000944A patent/MXPA05000944A/es active IP Right Grant
- 2003-07-23 DE DE60329615T patent/DE60329615D1/de not_active Expired - Lifetime
-
2005
- 2005-01-23 IL IL166451A patent/IL166451A/en not_active IP Right Cessation
- 2005-12-29 HK HK05112103.4A patent/HK1077578B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL166451A0 (en) | 2006-01-15 |
| EP1553086A1 (de) | 2005-07-13 |
| IL166451A (en) | 2011-07-31 |
| EP1553086B1 (de) | 2009-10-07 |
| AU2003252241A1 (en) | 2004-02-09 |
| KR20050019919A (ko) | 2005-03-03 |
| JP2004051592A (ja) | 2004-02-19 |
| CA2493036A1 (en) | 2004-01-29 |
| ATE444952T1 (de) | 2009-10-15 |
| KR101025528B1 (ko) | 2011-04-04 |
| HK1077578B (zh) | 2009-03-27 |
| CN100393702C (zh) | 2008-06-11 |
| MXPA05000944A (es) | 2005-10-18 |
| US7524967B2 (en) | 2009-04-28 |
| CN1671665A (zh) | 2005-09-21 |
| US20060004205A1 (en) | 2006-01-05 |
| AU2003252241B2 (en) | 2008-12-04 |
| HK1077578A1 (en) | 2006-02-17 |
| JP4208512B2 (ja) | 2009-01-14 |
| EP1553086A4 (de) | 2007-04-25 |
| WO2004009553A1 (ja) | 2004-01-29 |
| CA2493036C (en) | 2011-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |