DE60328195D1 - Menschliche monoklonale antikörper gegen interleukin-5 sowie diese umfassende verfahren und zusammensetzungen - Google Patents
Menschliche monoklonale antikörper gegen interleukin-5 sowie diese umfassende verfahren und zusammensetzungenInfo
- Publication number
- DE60328195D1 DE60328195D1 DE60328195T DE60328195T DE60328195D1 DE 60328195 D1 DE60328195 D1 DE 60328195D1 DE 60328195 T DE60328195 T DE 60328195T DE 60328195 T DE60328195 T DE 60328195T DE 60328195 D1 DE60328195 D1 DE 60328195D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- relates
- methods
- compositions
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36904402P | 2002-03-29 | 2002-03-29 | |
PCT/US2003/009260 WO2003085089A2 (en) | 2002-03-29 | 2003-03-27 | Human monoclonal antibodies to interleukin-5 and methods and compositions comprising same |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60328195D1 true DE60328195D1 (de) | 2009-08-13 |
Family
ID=28791919
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60328195T Expired - Lifetime DE60328195D1 (de) | 2002-03-29 | 2003-03-27 | Menschliche monoklonale antikörper gegen interleukin-5 sowie diese umfassende verfahren und zusammensetzungen |
Country Status (16)
Country | Link |
---|---|
US (2) | US7141653B2 (de) |
EP (1) | EP1527100B1 (de) |
JP (2) | JP2005530490A (de) |
CN (1) | CN1326879C (de) |
AT (1) | ATE435239T1 (de) |
AU (1) | AU2003220525A1 (de) |
CA (1) | CA2479927C (de) |
CY (1) | CY1109423T1 (de) |
DE (1) | DE60328195D1 (de) |
DK (1) | DK1527100T3 (de) |
ES (1) | ES2327830T3 (de) |
HK (1) | HK1070907A1 (de) |
MX (1) | MXPA04009418A (de) |
PT (1) | PT1527100E (de) |
SI (1) | SI1527100T1 (de) |
WO (1) | WO2003085089A2 (de) |
Families Citing this family (109)
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ES2568899T3 (es) | 1999-04-09 | 2016-05-05 | Kyowa Hakko Kirin Co., Ltd. | Procedimiento para controlar la actividad de una molécula inmunofuncional |
US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
MXPA04009418A (es) * | 2002-03-29 | 2005-06-08 | Schering Corp | Anticuerpos monoclonales humanos par interleucina-5, y metodos y composiciones que comprenden los mismos. |
DE60332483D1 (de) | 2002-11-15 | 2010-06-17 | Novartis Vaccines & Diagnostic | Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust |
PE20050925A1 (es) * | 2003-11-10 | 2005-11-29 | Schering Corp | Anticuerpo recombinante humanizado anti-interleuquina 10 |
RU2401277C2 (ru) | 2004-01-07 | 2010-10-10 | Чирон Корпорейшн | Не мышиное анти-m-csf-антитело (варианты), его получение и использование |
ES2395404T3 (es) * | 2004-05-14 | 2013-02-12 | Optimer Pharmaceuticals, Inc. | Tratamiento de las enfermedades asociadas al uso de antibióticos |
ATE541585T1 (de) * | 2004-10-28 | 2012-02-15 | Kyowa Hakko Kirin Co Ltd | Antikörper gegen il-5-rezeptor zur verwendung in der behandlung von endometriose. |
US8030003B2 (en) | 2004-12-07 | 2011-10-04 | Children's Hospital Medical Center | Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3 |
US20080233118A1 (en) * | 2005-07-28 | 2008-09-25 | Novartis Ag | Uses Of Antibody To M-Csf |
EP2311876A3 (de) * | 2005-07-28 | 2011-04-27 | Novartis AG | M-CSF-spezifischer monoklonaler Antikörper und Verwendungen davon |
US9062126B2 (en) | 2005-09-16 | 2015-06-23 | Raptor Pharmaceuticals Inc. | Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof |
SI2380592T1 (en) | 2005-11-14 | 2018-06-29 | Teva Pharmaceuticals International Gmbh | The antibody to the calcitonin-related peptide antagonist |
US7981414B2 (en) * | 2005-12-20 | 2011-07-19 | Cephalon Australia Pty Ltd | Anti-inflammatory dAb |
AU2007211829C9 (en) | 2006-02-01 | 2013-07-11 | Cephalon Australia Pty Ltd | Domain antibody construct |
US8278421B2 (en) | 2006-03-20 | 2012-10-02 | Xoma Techolology Ltd. | Human antibodies specific for gastrin materials and methods |
US20080038258A1 (en) * | 2006-07-21 | 2008-02-14 | Amgen Inc. | Polypeptides with Reduced Susceptibility to Oxidation and Methods of Making |
JP5148079B2 (ja) | 2006-07-25 | 2013-02-20 | 富士通株式会社 | 液冷ユニット用熱交換器および液冷ユニット並びに電子機器 |
JP4842040B2 (ja) | 2006-07-25 | 2011-12-21 | 富士通株式会社 | 電子機器 |
JP4781929B2 (ja) | 2006-07-25 | 2011-09-28 | 富士通株式会社 | 電子機器 |
JP2008027370A (ja) | 2006-07-25 | 2008-02-07 | Fujitsu Ltd | 電子機器 |
JP5406027B2 (ja) * | 2006-08-04 | 2014-02-05 | ノバルティス アーゲー | EphB3特異的抗体およびその使用 |
KR20140033241A (ko) | 2006-08-18 | 2014-03-17 | 노바르티스 아게 | Prlr 특이적 항체 및 그 용도 |
US20080132688A1 (en) * | 2006-09-22 | 2008-06-05 | Amgen Inc. | Methods for Removing Viral Contaminants During Protein Purification |
BRPI0717601A2 (pt) * | 2006-10-24 | 2013-10-22 | Trubion Pharmaceuticals Inc | Materiais e métodos para imunoglicoproteínas melhoradas |
US7846434B2 (en) * | 2006-10-24 | 2010-12-07 | Trubion Pharmaceuticals, Inc. | Materials and methods for improved immunoglycoproteins |
AU2007329307B2 (en) | 2006-12-07 | 2012-08-02 | Novartis Ag | Antagonist antibodies against EphB3 |
CN103405768A (zh) | 2006-12-20 | 2013-11-27 | 爱克索马技术有限公司 | 用于治疗IL-1β相关疾病的方法 |
AU2008214386B2 (en) | 2007-02-02 | 2013-09-19 | Amgen Inc | Hepcidin and hepcidin antibodies |
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EP2606906A1 (de) * | 2007-04-30 | 2013-06-26 | GlaxoSmithKline LLC | Verfahren zur Verabreichung von Anti-IL-5-Antikörpern |
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- 2003-03-27 EP EP03716836A patent/EP1527100B1/de not_active Expired - Lifetime
- 2003-03-27 AT AT03716836T patent/ATE435239T1/de active
- 2003-03-27 CN CNB038123975A patent/CN1326879C/zh not_active Expired - Lifetime
- 2003-03-27 ES ES03716836T patent/ES2327830T3/es not_active Expired - Lifetime
- 2003-03-27 PT PT03716836T patent/PT1527100E/pt unknown
- 2003-03-27 CA CA2479927A patent/CA2479927C/en not_active Expired - Fee Related
- 2003-03-27 AU AU2003220525A patent/AU2003220525A1/en not_active Abandoned
- 2003-03-27 US US10/401,344 patent/US7141653B2/en active Active
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JP2010011874A (ja) | 2010-01-21 |
HK1070907A1 (en) | 2005-06-30 |
DK1527100T3 (da) | 2009-09-07 |
SI1527100T1 (sl) | 2009-12-31 |
US7422742B2 (en) | 2008-09-09 |
AU2003220525A1 (en) | 2003-10-20 |
ATE435239T1 (de) | 2009-07-15 |
WO2003085089A2 (en) | 2003-10-16 |
EP1527100A2 (de) | 2005-05-04 |
CN1326879C (zh) | 2007-07-18 |
US20030194404A1 (en) | 2003-10-16 |
ES2327830T3 (es) | 2009-11-04 |
CA2479927C (en) | 2013-03-12 |
AU2003220525A8 (en) | 2003-10-20 |
CN1656122A (zh) | 2005-08-17 |
US20070025994A1 (en) | 2007-02-01 |
MXPA04009418A (es) | 2005-06-08 |
PT1527100E (pt) | 2009-08-25 |
JP2005530490A (ja) | 2005-10-13 |
CA2479927A1 (en) | 2003-10-16 |
EP1527100A4 (de) | 2006-06-14 |
EP1527100B1 (de) | 2009-07-01 |
US7141653B2 (en) | 2006-11-28 |
WO2003085089A3 (en) | 2005-03-10 |
CY1109423T1 (el) | 2014-08-13 |
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