DE60323607D1 - Verfahren zur rekombination genetischer elemente - Google Patents
Verfahren zur rekombination genetischer elementeInfo
- Publication number
- DE60323607D1 DE60323607D1 DE60323607T DE60323607T DE60323607D1 DE 60323607 D1 DE60323607 D1 DE 60323607D1 DE 60323607 T DE60323607 T DE 60323607T DE 60323607 T DE60323607 T DE 60323607T DE 60323607 D1 DE60323607 D1 DE 60323607D1
- Authority
- DE
- Germany
- Prior art keywords
- genetic elements
- recombining
- recombining genetic
- elements
- genetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36027902P | 2002-02-26 | 2002-02-26 | |
PCT/US2003/005708 WO2003072743A2 (en) | 2002-02-26 | 2003-02-26 | Method for the recombination of genetic elements |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60323607D1 true DE60323607D1 (de) | 2008-10-30 |
Family
ID=27766216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60323607T Expired - Lifetime DE60323607D1 (de) | 2002-02-26 | 2003-02-26 | Verfahren zur rekombination genetischer elemente |
Country Status (11)
Country | Link |
---|---|
US (1) | US7879582B2 (de) |
EP (1) | EP1476563B1 (de) |
JP (1) | JP4722396B2 (de) |
KR (1) | KR20040088538A (de) |
CN (1) | CN100475960C (de) |
AU (1) | AU2003216403A1 (de) |
CA (1) | CA2475547A1 (de) |
DE (1) | DE60323607D1 (de) |
IL (1) | IL162811A0 (de) |
NO (1) | NO20043985L (de) |
WO (1) | WO2003072743A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1965088A (zh) * | 2002-12-16 | 2007-05-16 | 纳幕尔杜邦公司 | 具有改善了的反应动力学的b12-依赖型脱水酶 |
AU2005286763A1 (en) | 2004-09-17 | 2006-03-30 | Biomarin Pharmaceutical, Inc. | Variants and chemically-modified variants of phenylalanine ammonia-lyase |
GB2432366B (en) * | 2005-11-19 | 2007-11-21 | Alligator Bioscience Ab | A method for in vitro molecular evolution of protein function |
US7531341B1 (en) | 2006-06-12 | 2009-05-12 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
US7534595B2 (en) | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
US7560263B2 (en) | 2007-08-17 | 2009-07-14 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof |
WO2010014225A2 (en) | 2008-07-30 | 2010-02-04 | Biomarin Pharmaceutical Inc. | Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase |
ES2690542T3 (es) | 2010-02-04 | 2018-11-21 | Biomarin Pharmaceutical Inc. | Método para purificar variantes de fenilalanina amoníaco-liasa procariotas |
EP2825647A4 (de) * | 2012-03-15 | 2015-10-14 | Codexis Inc | Gen-shuffleverfahren |
CA2886157A1 (en) | 2012-09-26 | 2014-04-03 | Butamax Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
WO2014201416A1 (en) * | 2013-06-14 | 2014-12-18 | Fred Hutchinson Cancer Research Center | Compositions for making random codon-mutant libraries and uses thereof |
JP6728556B2 (ja) * | 2016-08-05 | 2020-07-22 | ハイムバイオテック インコーポレイテッド | 一塩基多型検出用キット及び方法 |
WO2021168060A1 (en) * | 2020-02-19 | 2021-08-26 | Trustees Of Tufts College | Methods for engineering amino acid ammonia lyase enzymes and enzymes thereby obtained |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5605793A (en) * | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US5837458A (en) * | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
US5965408A (en) * | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
US6153410A (en) * | 1997-03-25 | 2000-11-28 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
US6365410B1 (en) * | 1999-05-19 | 2002-04-02 | Genencor International, Inc. | Directed evolution of microorganisms |
US6521748B2 (en) * | 1999-08-06 | 2003-02-18 | E. I. Du Pont De Nemours And Company | Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide |
JP4786844B2 (ja) * | 1999-08-06 | 2011-10-05 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | パラ−ヒドロキシ桂皮酸の生物学的製造 |
AUPQ974900A0 (en) | 2000-08-29 | 2000-09-21 | Macquarie Research Limited | Degenerate oligonucleotide gene-shuffling |
-
2003
- 2003-02-26 EP EP03743233A patent/EP1476563B1/de not_active Expired - Fee Related
- 2003-02-26 CN CNB038046261A patent/CN100475960C/zh not_active Expired - Fee Related
- 2003-02-26 IL IL16281103A patent/IL162811A0/xx unknown
- 2003-02-26 KR KR10-2004-7013224A patent/KR20040088538A/ko not_active Application Discontinuation
- 2003-02-26 DE DE60323607T patent/DE60323607D1/de not_active Expired - Lifetime
- 2003-02-26 AU AU2003216403A patent/AU2003216403A1/en not_active Abandoned
- 2003-02-26 JP JP2003571431A patent/JP4722396B2/ja not_active Expired - Fee Related
- 2003-02-26 CA CA002475547A patent/CA2475547A1/en not_active Abandoned
- 2003-02-26 US US10/374,366 patent/US7879582B2/en not_active Expired - Fee Related
- 2003-02-26 WO PCT/US2003/005708 patent/WO2003072743A2/en active Application Filing
-
2004
- 2004-09-23 NO NO20043985A patent/NO20043985L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2003216403A8 (en) | 2003-09-09 |
JP4722396B2 (ja) | 2011-07-13 |
US7879582B2 (en) | 2011-02-01 |
EP1476563B1 (de) | 2008-09-17 |
NO20043985L (no) | 2004-09-23 |
IL162811A0 (en) | 2005-11-20 |
CA2475547A1 (en) | 2003-09-04 |
WO2003072743A3 (en) | 2004-06-03 |
KR20040088538A (ko) | 2004-10-16 |
US20040014085A1 (en) | 2004-01-22 |
JP2005523690A (ja) | 2005-08-11 |
CN1630729A (zh) | 2005-06-22 |
WO2003072743A2 (en) | 2003-09-04 |
AU2003216403A1 (en) | 2003-09-09 |
EP1476563A4 (de) | 2006-02-01 |
CN100475960C (zh) | 2009-04-08 |
EP1476563A2 (de) | 2004-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |