DE60235005D1 - Nachweis der instabilität von mikrosatelliten und - Google Patents

Nachweis der instabilität von mikrosatelliten und

Info

Publication number
DE60235005D1
DE60235005D1 DE60235005T DE60235005T DE60235005D1 DE 60235005 D1 DE60235005 D1 DE 60235005D1 DE 60235005 T DE60235005 T DE 60235005T DE 60235005 T DE60235005 T DE 60235005T DE 60235005 D1 DE60235005 D1 DE 60235005D1
Authority
DE
Germany
Prior art keywords
instability
kits
methods
microsatellites
proof
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235005T
Other languages
English (en)
Inventor
Jeffery W Bacher
Laura Flanagan
Nadine Nassif
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Promega Corp
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of DE60235005D1 publication Critical patent/DE60235005D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Saccharide Compounds (AREA)
DE60235005T 2001-04-24 2002-04-24 Nachweis der instabilität von mikrosatelliten und Expired - Lifetime DE60235005D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/841,366 US20020058265A1 (en) 2000-09-15 2001-04-24 Detection of microsatellite instability and its use in diagnosis of tumors
PCT/US2002/012779 WO2002086448A2 (en) 2001-04-24 2002-04-24 Detection of microsatellite instability and its use in diagnosis of tumors

Publications (1)

Publication Number Publication Date
DE60235005D1 true DE60235005D1 (de) 2010-02-25

Family

ID=25284685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235005T Expired - Lifetime DE60235005D1 (de) 2001-04-24 2002-04-24 Nachweis der instabilität von mikrosatelliten und

Country Status (8)

Country Link
US (3) US20020058265A1 (de)
EP (1) EP1390538B1 (de)
JP (1) JP2004533241A (de)
AT (1) ATE454468T1 (de)
AU (1) AU2002303444A1 (de)
DE (1) DE60235005D1 (de)
ES (1) ES2338765T3 (de)
WO (1) WO2002086448A2 (de)

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US20020058265A1 (en) * 2000-09-15 2002-05-16 Promega Corporation Detection of microsatellite instability and its use in diagnosis of tumors
US6844152B1 (en) * 2000-09-15 2005-01-18 Promega Corporation Detection of microsatellite instability and its use in diagnosis of tumors
US20060088874A1 (en) * 2004-10-22 2006-04-27 Promega Corporation Methods and kits for detecting mutations
EP1809769A2 (de) 2004-10-22 2007-07-25 Redpath Integrated Pathology, Inc. Erhöhte vervielfältigbarkeit winziger gewebeproben, winzige gefärbte zytologieproben und andere winzige dna-quellen
JP4713138B2 (ja) * 2004-12-06 2011-06-29 株式会社日立ソリューションズ 遺伝子情報の表示方法及び表示装置及びプログラム
EP2218794A1 (de) * 2009-02-13 2010-08-18 Alphagenics International SA Instabilitätserkennung in Regionen mit genomischem DNA mit einfacher Tandemwiederholung
US20100317534A1 (en) * 2009-06-12 2010-12-16 Board Of Regents, The University Of Texas System Global germ line and tumor microsatellite patterns are cancer biomarkers
FR2960552B1 (fr) * 2010-06-01 2015-08-07 Ct Europ D Expertise Et De Rech Sur Les Agents Microbiens Ceeram Procede de genotypage de legionella pneumophila
FR2960553B1 (fr) * 2010-06-01 2014-09-05 Ct Europ D Expertise Et De Rech Sur Les Agents Microbiens Ceeram Procede de genotypage de staphylococcus aureus
US20120238464A1 (en) * 2011-03-18 2012-09-20 Baylor Research Institute Biomarkers for Predicting the Recurrence of Colorectal Cancer Metastasis
EP2744916A4 (de) 2011-07-13 2015-06-17 Primeradx Inc Multimodale verfahren zur simultanen erkennung und quantifizierung mehrerer nukleinsäuren in einer probe
JP5895290B2 (ja) * 2011-08-15 2016-03-30 有限会社カホテクノ 非ヒト被験体から取得した乳腺腫瘍サンプルが悪性腫瘍である可能性を診断する方法、システムおよびキット
US9341628B2 (en) 2012-11-30 2016-05-17 Interpace Diagnostics Corporation Methods for measuring carcinoembryonic antigen
US20140235456A1 (en) * 2012-12-17 2014-08-21 Virginia Tech Intellectual Properties, Inc. Methods and Compositions for Identifying Global Microsatellite Instability and for Characterizing Informative Microsatellite Loci
CN106701978A (zh) * 2017-01-24 2017-05-24 厦门艾德生物医药科技股份有限公司 一种人类微卫星不稳定性msi检测扩增引物组合物及试剂盒
EP3601615A4 (de) * 2017-03-20 2020-12-09 Caris MPI, Inc. Profilierung der genomischen stabilität
CN111373050A (zh) 2017-06-20 2020-07-03 生物辐射实验室股份有限公司 用于遗传不稳定性的数字扩增试验
US11773449B2 (en) 2017-09-01 2023-10-03 The Hospital For Sick Children Profiling and treatment of hypermutant cancer
KR20200055137A (ko) * 2017-10-19 2020-05-20 난토믹스, 엘엘씨 액체 생검으로부터의 msi (msi from liquid biopsies)
CN108866188B (zh) * 2018-07-12 2022-03-01 吉林大学 一种消化道恶性肿瘤易感性预测试剂盒及***
CN108676891B (zh) * 2018-07-12 2022-02-01 吉林大学 一种直肠腺癌易感性预测试剂盒及***
CN108841960B (zh) * 2018-07-12 2022-02-01 吉林大学 一种结肠腺癌易感性预测试剂盒及***
EP3739064A1 (de) 2019-05-15 2020-11-18 Biotype GmbH Vergleichende analyse von mikrosatelliten mittels kapillarelektrophorese (ce) -dna-profile
US20210147946A1 (en) * 2019-11-08 2021-05-20 Life Technologies Corporation Systems and assays for assessing microsatellite instability
CN110951851A (zh) * 2019-12-24 2020-04-03 北京优迅医学检验实验室有限公司 用于微卫星不稳定检测的引物组和方法
CN111763739B (zh) * 2020-08-11 2022-08-23 郑州科蒂亚生物技术有限公司 一种肿瘤微卫星不稳定检测引物及其应用和试剂盒

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Also Published As

Publication number Publication date
US7202031B2 (en) 2007-04-10
AU2002303444A1 (en) 2002-11-05
JP2004533241A (ja) 2004-11-04
US7749706B2 (en) 2010-07-06
US20070117136A1 (en) 2007-05-24
US20020058265A1 (en) 2002-05-16
ES2338765T3 (es) 2010-05-12
ATE454468T1 (de) 2010-01-15
WO2002086448A3 (en) 2003-11-13
WO2002086448A2 (en) 2002-10-31
EP1390538A2 (de) 2004-02-25
WO2002086448B1 (en) 2003-12-11
US20030180758A1 (en) 2003-09-25
EP1390538A4 (de) 2005-08-03
EP1390538B1 (de) 2010-01-06

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