DE60214138D1 - Isoxazolin-derivate als antidepressiva - Google Patents
Isoxazolin-derivate als antidepressivaInfo
- Publication number
- DE60214138D1 DE60214138D1 DE60214138T DE60214138T DE60214138D1 DE 60214138 D1 DE60214138 D1 DE 60214138D1 DE 60214138 T DE60214138 T DE 60214138T DE 60214138 T DE60214138 T DE 60214138T DE 60214138 D1 DE60214138 D1 DE 60214138D1
- Authority
- DE
- Germany
- Prior art keywords
- antidepressiva
- isoxazoline derivatives
- isoxazoline
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01200611 | 2001-02-21 | ||
EP01200611 | 2001-02-21 | ||
EP01201264 | 2001-04-05 | ||
EP01201264 | 2001-04-05 | ||
PCT/EP2002/001567 WO2002066484A1 (en) | 2001-02-21 | 2002-02-13 | Isoxazoline derivatives as anti-depressants |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60214138D1 true DE60214138D1 (de) | 2006-10-05 |
DE60214138T2 DE60214138T2 (de) | 2007-03-29 |
Family
ID=26076836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60214138T Expired - Lifetime DE60214138T2 (de) | 2001-02-21 | 2002-02-13 | Isoxazolin-derivate als antidepressiva |
Country Status (33)
Country | Link |
---|---|
US (1) | US7169786B2 (de) |
EP (1) | EP1368358B1 (de) |
JP (1) | JP3953424B2 (de) |
KR (1) | KR100848898B1 (de) |
CN (1) | CN100400540C (de) |
AR (1) | AR035685A1 (de) |
AT (1) | ATE337322T1 (de) |
AU (1) | AU2002244717B2 (de) |
BG (1) | BG107984A (de) |
BR (1) | BR0207433A (de) |
CA (1) | CA2437505C (de) |
CY (1) | CY1106448T1 (de) |
CZ (1) | CZ20032515A3 (de) |
DE (1) | DE60214138T2 (de) |
DK (1) | DK1368358T3 (de) |
EA (1) | EA006747B1 (de) |
EE (1) | EE200300398A (de) |
EG (1) | EG23929A (de) |
ES (1) | ES2271230T3 (de) |
HK (1) | HK1065537A1 (de) |
HR (1) | HRP20030647A2 (de) |
HU (1) | HUP0303270A3 (de) |
IL (2) | IL157470A0 (de) |
MX (1) | MXPA03007432A (de) |
MY (1) | MY137836A (de) |
NO (1) | NO20033700L (de) |
NZ (1) | NZ526741A (de) |
PL (1) | PL208593B1 (de) |
PT (1) | PT1368358E (de) |
SI (1) | SI1368358T1 (de) |
SK (1) | SK11612003A3 (de) |
TW (1) | TWI257392B (de) |
WO (1) | WO2002066484A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0203299D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel compounds |
WO2003082878A1 (en) | 2002-04-02 | 2003-10-09 | Janssen Pharmaceutica N.V. | Substituted amino isoxazoline derivatives and their use as anti-depressants. |
TW200409777A (en) * | 2002-08-12 | 2004-06-16 | Janssen Pharmaceutica Nv | C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants |
JP4478571B2 (ja) * | 2002-08-15 | 2010-06-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 縮合複素環式イソオキサゾリン誘導体及び抗うつ薬としてのそれらの使用 |
ES2301816T3 (es) * | 2002-08-21 | 2008-07-01 | Janssen Pharmaceutica Nv | Derivados de cromeno(4,3,c)isoxazolina sustituidos en c6 y c9 y su uso como antidepresivos. |
ZA200507486B (en) | 2003-03-07 | 2007-03-28 | Astellas Pharma Inc | Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl |
EP1944306A1 (de) * | 2003-09-17 | 2008-07-16 | Janssen Pharmaceutica, N.V. | Fusionierte heterocyclische Verbindungen |
ES2319539T3 (es) * | 2003-09-17 | 2009-05-08 | Janssen Pharmaceutica Nv | Compuestos heterociclicos condensados como moduladores del receptor de serotonina. |
DE602005016836D1 (de) * | 2004-11-26 | 2009-11-05 | Janssen Pharmaceutica Nv | Chotischer und anxiolytischer aktivität |
SG10201506994RA (en) * | 2007-03-09 | 2015-10-29 | Sanofi Aventis | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof |
CA2688405A1 (en) * | 2007-06-08 | 2008-12-18 | Helicon Therapeutics, Inc. | Therapeutic pyrazoloquinoline urea derivatives |
WO2009082268A2 (ru) | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
AR078171A1 (es) | 2009-09-15 | 2011-10-19 | Sanofi Aventis | Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0361577B1 (de) * | 1988-09-19 | 1993-05-05 | Akzo N.V. | Tetrahydronaphthalin und Indan-Derivate |
US5880121A (en) * | 1996-01-05 | 1999-03-09 | Hoechst Marion Roussel Inc. | 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof |
ES2182064T3 (es) * | 1996-04-12 | 2003-03-01 | Janssen Pharmaceutica Nv | Derivados de isoxazolidina. |
HUP9602763A3 (en) * | 1996-10-09 | 1999-05-28 | Egyt Gyogyszervegyeszeti Gyar | 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same |
CA2346396C (en) * | 1998-10-09 | 2009-04-28 | Janssen Pharmaceutica N.V. | 4,5-dihydro-isoxazole derivatives and their pharmaceutical use |
-
2002
- 2002-02-13 AU AU2002244717A patent/AU2002244717B2/en not_active Expired
- 2002-02-13 EE EEP200300398A patent/EE200300398A/xx unknown
- 2002-02-13 PT PT02712909T patent/PT1368358E/pt unknown
- 2002-02-13 DE DE60214138T patent/DE60214138T2/de not_active Expired - Lifetime
- 2002-02-13 MX MXPA03007432A patent/MXPA03007432A/es active IP Right Grant
- 2002-02-13 EA EA200300915A patent/EA006747B1/ru not_active IP Right Cessation
- 2002-02-13 JP JP2002565998A patent/JP3953424B2/ja not_active Expired - Lifetime
- 2002-02-13 US US10/468,555 patent/US7169786B2/en not_active Expired - Lifetime
- 2002-02-13 ES ES02712909T patent/ES2271230T3/es not_active Expired - Lifetime
- 2002-02-13 SI SI200230433T patent/SI1368358T1/sl unknown
- 2002-02-13 CA CA2437505A patent/CA2437505C/en not_active Expired - Lifetime
- 2002-02-13 CZ CZ20032515A patent/CZ20032515A3/cs unknown
- 2002-02-13 EP EP02712909A patent/EP1368358B1/de not_active Expired - Lifetime
- 2002-02-13 SK SK1161-2003A patent/SK11612003A3/sk unknown
- 2002-02-13 IL IL15747002A patent/IL157470A0/xx unknown
- 2002-02-13 BR BR0207433-8A patent/BR0207433A/pt not_active IP Right Cessation
- 2002-02-13 HU HU0303270A patent/HUP0303270A3/hu unknown
- 2002-02-13 DK DK02712909T patent/DK1368358T3/da active
- 2002-02-13 CN CNB028052439A patent/CN100400540C/zh not_active Expired - Fee Related
- 2002-02-13 NZ NZ526741A patent/NZ526741A/en unknown
- 2002-02-13 KR KR1020037008328A patent/KR100848898B1/ko not_active IP Right Cessation
- 2002-02-13 AT AT02712909T patent/ATE337322T1/de not_active IP Right Cessation
- 2002-02-13 WO PCT/EP2002/001567 patent/WO2002066484A1/en active IP Right Grant
- 2002-02-13 PL PL363264A patent/PL208593B1/pl unknown
- 2002-02-19 EG EG20020197A patent/EG23929A/xx active
- 2002-02-19 MY MYPI20020548A patent/MY137836A/en unknown
- 2002-02-20 AR ARP020100583A patent/AR035685A1/es unknown
- 2002-02-20 TW TW091102853A patent/TWI257392B/zh not_active IP Right Cessation
-
2003
- 2003-07-08 BG BG107984A patent/BG107984A/bg unknown
- 2003-08-12 HR HR20030647A patent/HRP20030647A2/hr not_active Application Discontinuation
- 2003-08-19 IL IL157470A patent/IL157470A/en unknown
- 2003-08-20 NO NO20033700A patent/NO20033700L/no not_active Application Discontinuation
-
2004
- 2004-10-25 HK HK04108329.1A patent/HK1065537A1/xx not_active IP Right Cessation
-
2006
- 2006-11-22 CY CY20061101693T patent/CY1106448T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |