DE60214138D1 - Isoxazolin-derivate als antidepressiva - Google Patents

Isoxazolin-derivate als antidepressiva

Info

Publication number: DE60214138D1
Authority: DE; Germany
Prior art keywords: antidepressiva; isoxazoline derivatives; isoxazoline; derivatives
Prior art date: 2001-02-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60214138T

Other languages

English (en)

Other versions

DE60214138T2 (de

Inventor

J I Andres-Gil

F J Fernandez-Gadea

M J Alcazar-Vaca

J M Cid-Nunez

J Pastor-Fernandez

A A H P Megens

G I C M Heylen

X J M Langlois

M H M Bakker

T H W Steckler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Janssen Pharmaceutica NV

Original Assignee

Janssen Pharmaceutica NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-21

Filing date

2002-02-13

Publication date

2006-10-05

2002-02-13 Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV

2006-10-05 Application granted granted Critical

2006-10-05 Publication of DE60214138D1 publication Critical patent/DE60214138D1/de

2007-03-29 Publication of DE60214138T2 publication Critical patent/DE60214138T2/de

2022-02-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DE60214138T 2001-02-21 2002-02-13 Isoxazolin-derivate als antidepressiva Expired - Lifetime DE60214138T2 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
EP01200611		2001-02-21
EP01200611		2001-02-21
EP01201264		2001-04-05
EP01201264		2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en)	2001-02-21	2002-02-13	Isoxazoline derivatives as anti-depressants

Publications (2)

Publication Number	Publication Date
DE60214138D1 true DE60214138D1 (de)	2006-10-05
DE60214138T2 DE60214138T2 (de)	2007-03-29

Family

ID=26076836

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60214138T Expired - Lifetime DE60214138T2 (de)	2001-02-21	2002-02-13	Isoxazolin-derivate als antidepressiva

Country Status (33)

Country	Link
US (1)	US7169786B2 (de)
EP (1)	EP1368358B1 (de)
JP (1)	JP3953424B2 (de)
KR (1)	KR100848898B1 (de)
CN (1)	CN100400540C (de)
AR (1)	AR035685A1 (de)
AT (1)	ATE337322T1 (de)
AU (1)	AU2002244717B2 (de)
BG (1)	BG107984A (de)
BR (1)	BR0207433A (de)
CA (1)	CA2437505C (de)
CY (1)	CY1106448T1 (de)
CZ (1)	CZ20032515A3 (de)
DE (1)	DE60214138T2 (de)
DK (1)	DK1368358T3 (de)
EA (1)	EA006747B1 (de)
EE (1)	EE200300398A (de)
EG (1)	EG23929A (de)
ES (1)	ES2271230T3 (de)
HK (1)	HK1065537A1 (de)
HR (1)	HRP20030647A2 (de)
HU (1)	HUP0303270A3 (de)
IL (2)	IL157470A0 (de)
MX (1)	MXPA03007432A (de)
MY (1)	MY137836A (de)
NO (1)	NO20033700L (de)
NZ (1)	NZ526741A (de)
PL (1)	PL208593B1 (de)
PT (1)	PT1368358E (de)
SI (1)	SI1368358T1 (de)
SK (1)	SK11612003A3 (de)
TW (1)	TWI257392B (de)
WO (1)	WO2002066484A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0203299D0 (en) *	2002-02-12	2002-03-27	Glaxo Group Ltd	Novel compounds
WO2003082878A1 (en)	2002-04-02	2003-10-09	Janssen Pharmaceutica N.V.	Substituted amino isoxazoline derivatives and their use as anti-depressants.
TW200409777A (en) *	2002-08-12	2004-06-16	Janssen Pharmaceutica Nv	C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
JP4478571B2 (ja) *	2002-08-15	2010-06-09	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	縮合複素環式イソオキサゾリン誘導体及び抗うつ薬としてのそれらの使用
ES2301816T3 (es) *	2002-08-21	2008-07-01	Janssen Pharmaceutica Nv	Derivados de cromeno(4,3,c)isoxazolina sustituidos en c6 y c9 y su uso como antidepresivos.
ZA200507486B (en)	2003-03-07	2007-03-28	Astellas Pharma Inc	Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl
EP1944306A1 (de) *	2003-09-17	2008-07-16	Janssen Pharmaceutica, N.V.	Fusionierte heterocyclische Verbindungen
ES2319539T3 (es) *	2003-09-17	2009-05-08	Janssen Pharmaceutica Nv	Compuestos heterociclicos condensados como moduladores del receptor de serotonina.
DE602005016836D1 (de) *	2004-11-26	2009-11-05	Janssen Pharmaceutica Nv	Chotischer und anxiolytischer aktivität
SG10201506994RA (en) *	2007-03-09	2015-10-29	Sanofi Aventis	Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
CA2688405A1 (en) *	2007-06-08	2008-12-18	Helicon Therapeutics, Inc.	Therapeutic pyrazoloquinoline urea derivatives
WO2009082268A2 (ru)	2007-12-21	2009-07-02	Alla Chem, Llc	ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ
AR078171A1 (es)	2009-09-15	2011-10-19	Sanofi Aventis	Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0361577B1 (de) *	1988-09-19	1993-05-05	Akzo N.V.	Tetrahydronaphthalin und Indan-Derivate
US5880121A (en) *	1996-01-05	1999-03-09	Hoechst Marion Roussel Inc.	4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
ES2182064T3 (es) *	1996-04-12	2003-03-01	Janssen Pharmaceutica Nv	Derivados de isoxazolidina.
HUP9602763A3 (en) *	1996-10-09	1999-05-28	Egyt Gyogyszervegyeszeti Gyar	3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
CA2346396C (en) *	1998-10-09	2009-04-28	Janssen Pharmaceutica N.V.	4,5-dihydro-isoxazole derivatives and their pharmaceutical use

2002
- 2002-02-13 AU AU2002244717A patent/AU2002244717B2/en not_active Expired
- 2002-02-13 EE EEP200300398A patent/EE200300398A/xx unknown
- 2002-02-13 PT PT02712909T patent/PT1368358E/pt unknown
- 2002-02-13 DE DE60214138T patent/DE60214138T2/de not_active Expired - Lifetime
- 2002-02-13 MX MXPA03007432A patent/MXPA03007432A/es active IP Right Grant
- 2002-02-13 EA EA200300915A patent/EA006747B1/ru not_active IP Right Cessation
- 2002-02-13 JP JP2002565998A patent/JP3953424B2/ja not_active Expired - Lifetime
- 2002-02-13 US US10/468,555 patent/US7169786B2/en not_active Expired - Lifetime
- 2002-02-13 ES ES02712909T patent/ES2271230T3/es not_active Expired - Lifetime
- 2002-02-13 SI SI200230433T patent/SI1368358T1/sl unknown
- 2002-02-13 CA CA2437505A patent/CA2437505C/en not_active Expired - Lifetime
- 2002-02-13 CZ CZ20032515A patent/CZ20032515A3/cs unknown
- 2002-02-13 EP EP02712909A patent/EP1368358B1/de not_active Expired - Lifetime
- 2002-02-13 SK SK1161-2003A patent/SK11612003A3/sk unknown
- 2002-02-13 IL IL15747002A patent/IL157470A0/xx unknown
- 2002-02-13 BR BR0207433-8A patent/BR0207433A/pt not_active IP Right Cessation
- 2002-02-13 HU HU0303270A patent/HUP0303270A3/hu unknown
- 2002-02-13 DK DK02712909T patent/DK1368358T3/da active
- 2002-02-13 CN CNB028052439A patent/CN100400540C/zh not_active Expired - Fee Related
- 2002-02-13 NZ NZ526741A patent/NZ526741A/en unknown
- 2002-02-13 KR KR1020037008328A patent/KR100848898B1/ko not_active IP Right Cessation
- 2002-02-13 AT AT02712909T patent/ATE337322T1/de not_active IP Right Cessation
- 2002-02-13 WO PCT/EP2002/001567 patent/WO2002066484A1/en active IP Right Grant
- 2002-02-13 PL PL363264A patent/PL208593B1/pl unknown
- 2002-02-19 EG EG20020197A patent/EG23929A/xx active
- 2002-02-19 MY MYPI20020548A patent/MY137836A/en unknown
- 2002-02-20 AR ARP020100583A patent/AR035685A1/es unknown
- 2002-02-20 TW TW091102853A patent/TWI257392B/zh not_active IP Right Cessation
2003
- 2003-07-08 BG BG107984A patent/BG107984A/bg unknown
- 2003-08-12 HR HR20030647A patent/HRP20030647A2/hr not_active Application Discontinuation
- 2003-08-19 IL IL157470A patent/IL157470A/en unknown
- 2003-08-20 NO NO20033700A patent/NO20033700L/no not_active Application Discontinuation
2004
- 2004-10-25 HK HK04108329.1A patent/HK1065537A1/xx not_active IP Right Cessation
2006
- 2006-11-22 CY CY20061101693T patent/CY1106448T1/el unknown

Also Published As

Publication number	Publication date
HK1065537A1 (en)	2005-02-25
CN1492871A (zh)	2004-04-28
KR100848898B1 (ko)	2008-07-29
CZ20032515A3 (cs)	2003-12-17
MY137836A (en)	2009-03-31
SK11612003A3 (sk)	2004-04-06
BG107984A (bg)	2004-09-30
HRP20030647A2 (en)	2005-06-30
PT1368358E (pt)	2007-01-31
EA200300915A1 (ru)	2004-06-24
CN100400540C (zh)	2008-07-09
US7169786B2 (en)	2007-01-30
MXPA03007432A (es)	2003-11-18
US20040122037A1 (en)	2004-06-24
CY1106448T1 (el)	2011-10-12
AU2002244717B2 (en)	2007-07-19
DE60214138T2 (de)	2007-03-29
SI1368358T1 (sl)	2007-02-28
EP1368358B1 (de)	2006-08-23
EA006747B1 (ru)	2006-04-28
NZ526741A (en)	2004-04-30
DK1368358T3 (da)	2007-01-02
EE200300398A (et)	2003-12-15
CA2437505C (en)	2010-02-09
PL363264A1 (en)	2004-11-15
BR0207433A (pt)	2004-06-01
NO20033700D0 (no)	2003-08-20
JP2004518748A (ja)	2004-06-24
AR035685A1 (es)	2004-06-23
CA2437505A1 (en)	2002-08-29
EG23929A (en)	2008-01-14
IL157470A0 (en)	2004-03-28
PL208593B1 (pl)	2011-05-31
WO2002066484A1 (en)	2002-08-29
ES2271230T3 (es)	2007-04-16
HUP0303270A2 (hu)	2004-01-28
NO20033700L (no)	2003-10-21
KR20030076590A (ko)	2003-09-26
JP3953424B2 (ja)	2007-08-08
ATE337322T1 (de)	2006-09-15
HUP0303270A3 (en)	2007-03-28
IL157470A (en)	2008-07-08
EP1368358A1 (de)	2003-12-10
TWI257392B (en)	2006-07-01

Legal Events

Date	Code	Title	Description
2007-09-13	8364	No opposition during term of opposition

Publication	Publication Date	Title
DE60134094D1 (de)	2008-07-03	C7-taxanester als antitumormittel
ATE319451T1 (de)	2006-03-15	Tetrahydrochinolin-derivate
ATE288913T1 (de)	2005-02-15	N-heterocyclylsubstituierte thienyloxy-pyrimidine als herbizide
DE50304983D1 (de)	2006-10-19	Heteroaryloxy-substituierte phenylaminopyrimidine als rho-kinaseinhibitoren
DE60330694D1 (de)	2010-02-04	Pyrimidopyrimidone als kinaseinhibitoren
DE602004015724D1 (de)	2008-09-25	Diazepinoindolderivate als kinaseinhibitoren
ATE312827T1 (de)	2005-12-15	3-substituierte-4-pyrimidonderivate
DE602004024420D1 (de)	2010-01-14	Chinazolinderivate als antitumormittel
NO20033572D0 (no)	2003-08-12	Viskoelastiske blandinger
ATE437862T1 (de)	2009-08-15	Pyrimidin-5-onderivate als ldl-pla2 inhibitoren
ATE402148T1 (de)	2008-08-15	Substituierte pyridinylamine
DE50206892D1 (de)	2006-06-29	Substituierte imidazotriazinone
EE200300447A (et)	2003-12-15	Asendatud bensofuraan-2-karboksamiidide derivaadid
DE50204551D1 (de)	2005-11-17	Kugelgelenk
FR2825343B1 (fr)	2003-11-28	Etiqueteuse
DE60214138D1 (de)	2006-10-05	Isoxazolin-derivate als antidepressiva
DE60202672D1 (de)	2005-02-24	5-halogen-6-phenyl-7-fluoroalkylamino-triazolopyrimidine als fungizide
DK1373228T3 (da)	2008-08-04	Substituerede fluoralkoxyphenylsulfonylurinstoffer
IS2523B (is)	2009-07-15	Turn vindorkuvers
DE602004004295D1 (de)	2007-02-22	6-ä(substituiertes)phenylütriazolopyrimidine als antikrebsmittel
DE60223031D1 (de)	2007-11-29	Arylpiperazin gebundene tetrahydroindolonderivate
ATE394372T1 (de)	2008-05-15	G-lactamderivate als prostaglandinagonisten
DK1406858T3 (da)	2009-11-23	Substituerede 4-aminocyklohexanoler
DE60201463D1 (de)	2004-11-11	Indanon-Derivate als Duftstoffe
DE50209313D1 (de)	2007-03-08	Selektive arylguanidinpeptide als urokinaseinhibitoren