DE60209248D1 - Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen - Google Patents

Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen

Info

Publication number
DE60209248D1
DE60209248D1 DE60209248T DE60209248T DE60209248D1 DE 60209248 D1 DE60209248 D1 DE 60209248D1 DE 60209248 T DE60209248 T DE 60209248T DE 60209248 T DE60209248 T DE 60209248T DE 60209248 D1 DE60209248 D1 DE 60209248D1
Authority
DE
Germany
Prior art keywords
estra
benzodioxol
dien
hydroxy
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60209248T
Other languages
English (en)
Inventor
Cornelis Sennef
Bernardus Wijnand M Peeters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of DE60209248D1 publication Critical patent/DE60209248D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60209248T 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen Expired - Lifetime DE60209248D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204072 2001-10-26
PCT/EP2002/011732 WO2003037354A1 (en) 2001-10-26 2002-10-21 USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

Publications (1)

Publication Number Publication Date
DE60209248D1 true DE60209248D1 (de) 2006-04-20

Family

ID=8181136

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60230936T Expired - Lifetime DE60230936D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen
DE60209248T Expired - Lifetime DE60209248D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60230936T Expired - Lifetime DE60230936D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen

Country Status (27)

Country Link
US (1) US20040266863A1 (de)
EP (2) EP1441739B1 (de)
JP (1) JP4647909B2 (de)
KR (1) KR20050038580A (de)
CN (1) CN100531738C (de)
AT (2) ATE317700T1 (de)
AU (1) AU2002348996B2 (de)
BR (1) BR0213466A (de)
CA (1) CA2463446C (de)
CY (1) CY1110173T1 (de)
DE (2) DE60230936D1 (de)
DK (1) DK1652526T3 (de)
EC (1) ECSP045080A (de)
ES (1) ES2319563T3 (de)
HK (1) HK1087357A1 (de)
HR (1) HRP20040370B1 (de)
HU (1) HUP0500070A3 (de)
IL (2) IL161248A0 (de)
IS (1) IS2702B (de)
MX (1) MXPA04003781A (de)
NO (1) NO332978B1 (de)
NZ (1) NZ532429A (de)
PL (1) PL206687B1 (de)
PT (1) PT1652526E (de)
RU (1) RU2302245C2 (de)
WO (1) WO2003037354A1 (de)
ZA (1) ZA200403088B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080061A1 (en) * 2003-07-23 2005-04-14 Corcept Therapeutics, Inc. Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
AU2011236053B2 (en) * 2004-11-19 2014-06-26 Merck Sharpe & Dohme B.V. Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CN103316019B (zh) * 2004-11-19 2015-10-28 默沙东有限责任公司 用于治疗抑郁症的包含选择性5-羟色胺再摄取抑制剂和糖皮质激素受体拮抗剂的药物组合
JP2009535430A (ja) * 2006-05-02 2009-10-01 コーセプト セラピューティクス， インコーポレイテッド Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用
US8658128B2 (en) 2011-02-03 2014-02-25 Pop Test Cortisol Llc System and method for diagnosis and treatment
EP2699245A4 (de) * 2011-04-18 2014-12-10 Pop Test Cortisol Llc Behandlung von haarausfall
US8986677B2 (en) * 2012-07-30 2015-03-24 Pop Test Cortisol Llc Therapeutic compositions and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814333A (en) * 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) * 1997-06-30 1999-01-28 Forschungszentrum Juelich Gmbh Magnetflußsensor mit ringförmiger Sonde
ATE332696T1 (de) * 1997-10-06 2006-08-15 Univ Leland Stanford Junior Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
PT1370268E (pt) * 2001-03-23 2009-08-26 Corcept Therapeutics Inc Métodos de tratamento de perturbações de stress usando antagonistas específicos dos receptores de glucocorticóides
WO2002096433A1 (en) * 2001-05-04 2002-12-05 Corcept Therapeutics, Inc. Methods for treating delirium using glucocorticoid receptor-specific antagonists
CA2459033C (en) * 2001-08-31 2012-05-22 Corcept Therapeutics, Inc. Methods for inhibiting cognitive deterioration in adults with down's syndrome

Also Published As

Publication number Publication date
IS2702B (is) 2010-11-15
HRP20040370A2 (en) 2004-08-31
ES2319563T3 (es) 2009-05-08
NO332978B1 (no) 2013-02-11
HUP0500070A2 (hu) 2005-04-28
IL161248A0 (en) 2004-09-27
DK1652526T3 (da) 2009-05-18
ATE317700T1 (de) 2006-03-15
ZA200403088B (en) 2005-01-24
NO20041651L (no) 2004-04-23
RU2302245C2 (ru) 2007-07-10
RU2004116082A (ru) 2005-05-10
MXPA04003781A (es) 2004-07-30
CY1110173T1 (el) 2015-01-14
CN1582153A (zh) 2005-02-16
ECSP045080A (es) 2004-06-28
EP1652526A3 (de) 2006-08-02
IS7204A (is) 2004-03-31
PT1652526E (pt) 2009-02-06
CA2463446C (en) 2010-02-23
CN100531738C (zh) 2009-08-26
US20040266863A1 (en) 2004-12-30
NZ532429A (en) 2004-10-29
CA2463446A1 (en) 2003-05-08
HRP20040370B1 (en) 2012-09-30
AU2002348996B2 (en) 2008-06-05
JP2005521637A (ja) 2005-07-21
KR20050038580A (ko) 2005-04-27
BR0213466A (pt) 2004-11-09
DE60230936D1 (de) 2009-03-05
ATE420649T1 (de) 2009-01-15
EP1652526B1 (de) 2009-01-14
JP4647909B2 (ja) 2011-03-09
IL161248A (en) 2010-12-30
HUP0500070A3 (en) 2012-09-28
HK1087357A1 (en) 2006-10-13
WO2003037354A1 (en) 2003-05-08
EP1441739B1 (de) 2006-02-15
PL369261A1 (en) 2005-04-18
EP1441739A1 (de) 2004-08-04
PL206687B1 (pl) 2010-09-30
EP1652526A2 (de) 2006-05-03

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8372 Publication of ep patent withdrawn