DE60204633T2 - Sulfonyl-Heteroaryl-Triazole als entzündungshemmende und analgetische Mittel - Google Patents

Sulfonyl-Heteroaryl-Triazole als entzündungshemmende und analgetische Mittel Download PDF

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Publication number
DE60204633T2
DE60204633T2 DE60204633T DE60204633T DE60204633T2 DE 60204633 T2 DE60204633 T2 DE 60204633T2 DE 60204633 T DE60204633 T DE 60204633T DE 60204633 T DE60204633 T DE 60204633T DE 60204633 T2 DE60204633 T2 DE 60204633T2
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Prior art keywords
triazoles
sulfonyl
heteroaryl
inflammatory
analgesic agents
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Expired - Fee Related
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DE60204633T
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DE60204633D1 (de
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Subas Man Sakya
Andrei Shavnya
Bryson Rast
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Pfizer Products Inc
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Pfizer Products Inc
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    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
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  • Cardiology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
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DE60204633T 2001-07-05 2002-07-01 Sulfonyl-Heteroaryl-Triazole als entzündungshemmende und analgetische Mittel Expired - Fee Related DE60204633T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30323201P 2001-07-05 2001-07-05

Publications (2)

Publication Number Publication Date
DE60204633D1 DE60204633D1 (de) 2005-07-21
DE60204633T2 true DE60204633T2 (de) 2006-06-14

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DE60204633T Expired - Fee Related DE60204633T2 (de) 2001-07-05 2002-07-01 Sulfonyl-Heteroaryl-Triazole als entzündungshemmende und analgetische Mittel

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US (2) US6753332B2 (de)
EP (1) EP1273580B1 (de)
JP (1) JP2003040887A (de)
AT (1) ATE297913T1 (de)
BR (1) BR0202546A (de)
CA (1) CA2392271C (de)
DE (1) DE60204633T2 (de)
ES (1) ES2240661T3 (de)
MX (1) MXPA02006723A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100686537B1 (ko) * 2001-12-28 2007-02-27 씨제이 주식회사 사이클로옥시게나제-2 의 저해제로서 선택성이 뛰어난디아릴 1,2,4-트리아졸 유도체
KR100467668B1 (ko) * 2002-08-07 2005-01-24 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
US7074809B2 (en) * 2002-08-09 2006-07-11 Astrazeneca Ab Compounds
KR100491317B1 (ko) * 2002-11-26 2005-05-24 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
BRPI0414663A (pt) * 2003-09-22 2006-11-21 Pfizer derivados triazol substituìdos como antagonistas de oxitocina
TW200835487A (en) * 2006-12-28 2008-09-01 Basf Ag 2-substituted pyridines I in therapy
DE112010001898T5 (de) 2009-04-27 2012-08-02 Dow Agrosciences Llc Insektizide Pyridinverbindungen
EP2527335B1 (de) 2011-04-26 2013-09-18 King Saud University Triazolderivate als Entzündungshemmer
US8853248B2 (en) * 2012-04-05 2014-10-07 Hubert Maehr (1,2,3-triazolyl)sulfonyl derivatives
CN112142716B (zh) * 2020-10-29 2021-08-31 山东新时代药业有限公司 一种5元杂芳基取代的吡嗪衍生物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
EP0003895A1 (de) 1978-02-16 1979-09-05 E.R. Squibb & Sons, Inc. 1-Acyl-3(5)-alkyl-5(3)-phenyl-1,2,4-triazole, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4259504A (en) 1979-08-27 1981-03-31 American Cyanamid Company Substituted 1H-1,2,4-triazoles
HU193891B (en) 1984-02-07 1987-12-28 Gyogyszerkutato Intezet Process for production of new derivatives of 1,2,4-triasole
US5256680A (en) 1988-11-29 1993-10-26 Warner-Lambert Company 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxy-phenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents
US5066668A (en) 1989-06-09 1991-11-19 Warner-Lambert Co. Triazole derivatives of fenamates as antiinflammatory agents
US4962119A (en) 1989-06-09 1990-10-09 Warner-Lambert Company Triazole derivatives of fenamates as antiinflammatory agents
CA2327185A1 (en) * 1998-04-08 1999-10-14 Abbott Laboratories Pyrazole inhibitors of cytokine production
EP1099695A1 (de) * 1999-11-09 2001-05-16 Laboratoire Theramex S.A. 5-Aryl-1H-1,2,4-triazolverbindungen als Cyclooxygenase-2 Inhibitoren und diese enthaltende pharmazeutische Zusammensetzungen
DE60001623T2 (de) 1999-12-03 2003-12-18 Pfizer Products Inc., Groton Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel

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ES2240661T3 (es) 2005-10-16
ATE297913T1 (de) 2005-07-15
US6753332B2 (en) 2004-06-22
US6875779B2 (en) 2005-04-05
DE60204633D1 (de) 2005-07-21
MXPA02006723A (es) 2003-01-23
US20040198735A1 (en) 2004-10-07
CA2392271A1 (en) 2003-01-05
JP2003040887A (ja) 2003-02-13
BR0202546A (pt) 2003-05-13
CA2392271C (en) 2006-08-29
EP1273580B1 (de) 2005-06-15
US20030119835A1 (en) 2003-06-26
EP1273580A1 (de) 2003-01-08

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