DE602007010254D1 - Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack - Google Patents

Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack

Info

Publication number
DE602007010254D1
DE602007010254D1 DE602007010254T DE602007010254T DE602007010254D1 DE 602007010254 D1 DE602007010254 D1 DE 602007010254D1 DE 602007010254 T DE602007010254 T DE 602007010254T DE 602007010254 T DE602007010254 T DE 602007010254T DE 602007010254 D1 DE602007010254 D1 DE 602007010254D1
Authority
DE
Germany
Prior art keywords
solid dosage
active agent
dosage form
taste
taste masked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007010254T
Other languages
English (en)
Inventor
Alexander Mark Schobel
Shyam Sundar Kumar Sarma Vangala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE602007010254D1 publication Critical patent/DE602007010254D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE602007010254T 2006-03-16 2007-03-15 Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack Active DE602007010254D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78318906P 2006-03-16 2006-03-16
PCT/US2007/006452 WO2007109057A2 (en) 2006-03-16 2007-03-15 Solid dosage form containing a taste masked active agent

Publications (1)

Publication Number Publication Date
DE602007010254D1 true DE602007010254D1 (de) 2010-12-16

Family

ID=38372464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007010254T Active DE602007010254D1 (de) 2006-03-16 2007-03-15 Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack

Country Status (15)

Country Link
US (2) US8986735B2 (de)
EP (1) EP1998762B1 (de)
JP (1) JP5242543B2 (de)
CN (1) CN101404990B (de)
AT (1) ATE486593T1 (de)
AU (1) AU2007227614B2 (de)
BR (1) BRPI0709382A2 (de)
CA (1) CA2643944C (de)
DE (1) DE602007010254D1 (de)
ES (1) ES2355306T3 (de)
MX (1) MX2008011823A (de)
PL (1) PL1998762T3 (de)
PT (1) PT1998762E (de)
RU (1) RU2437657C2 (de)
WO (1) WO2007109057A2 (de)

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JP5242543B2 (ja) * 2006-03-16 2013-07-24 ノバルティス アーゲー 味をマスキングした活性薬剤を含有する固体剤形
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
KR20120056824A (ko) 2009-08-19 2012-06-04 바이엘 파마 악티엔게젤샤프트 소아과 용도를 위한 약물 전달 시스템 （웨이퍼）
JP6050564B2 (ja) * 2010-03-11 2016-12-21 テイカ製薬株式会社 フィルム状製剤
JP2012031164A (ja) * 2010-07-06 2012-02-16 Teika Seiyaku Kk フィルム状製剤
JP5853460B2 (ja) * 2010-07-30 2016-02-09 大正製薬株式会社 内服液剤
WO2012095746A2 (en) 2011-01-11 2012-07-19 Capsugel Belgium Nv New hard capsules
JP6067687B2 (ja) * 2011-06-08 2017-01-25 エルテーエス ローマン テラピー−ジステーメ アーゲー 味覚マスキングのためのイオン交換樹脂を含有する可食性経口ストリップ又はウエハース剤形
WO2013129889A2 (ko) 2012-02-28 2013-09-06 주식회사 서울제약 실데나필을 유효성분으로 함유하며 고미가 은폐된 고함량 속용필름
KR101328350B1 (ko) 2012-02-28 2013-11-11 주식회사 서울제약 실데나필 또는 이의 약제학적으로 허용되는 염을 유효성분으로 함유하는 고미가 은폐된 약제학적 조성물
JP2013231011A (ja) * 2012-05-01 2013-11-14 Sawai Pharmaceutical Co Ltd アトルバスタチン含有医薬組成物およびそれを用いた口腔内崩壊錠
NZ727834A (en) * 2014-06-24 2020-08-28 Taho Pharmaceuticals Ltd Fast acting orally disintegrating film
WO2016009001A1 (en) * 2014-07-17 2016-01-21 Hexal Ag Orodispersible film
CN104257637A (zh) * 2014-09-26 2015-01-07 天津市聚星康华医药科技有限公司 一种酮洛芬口腔速溶膜及其制备方法
WO2018129079A1 (en) * 2017-01-03 2018-07-12 Thermolife International, Llc Method of isolating theacrine and composition comprising theacrine
EP3565532A4 (de) * 2017-01-04 2020-10-28 Bonayo Lifesciences Private Limited Oral dispergierbare filmzusammensetzung
CN110678170A (zh) 2017-04-14 2020-01-10 比利时胶囊公司 普鲁兰多糖胶囊
BR112019021396A2 (pt) 2017-04-14 2020-04-28 Capsugel Belgium Nv processo para fabricação de pululano
CN108113962B (zh) * 2018-02-23 2021-06-25 成都中医药大学 一种降低含有多酚的中药口服制剂涩味的方法

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US4145440A (en) 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4361580A (en) 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
GB8813682D0 (en) 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
US5032384A (en) 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5416181A (en) 1989-02-10 1995-05-16 Penford Products Company Reinforced films made from water soluble polymers
CA2021548A1 (en) 1989-09-01 1991-03-02 Ronald Nash Duvall Effervescent cold or sinus allergy medicine composition having reduced sodium content
US5262179A (en) 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
DE4018247A1 (de) 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen
US5024997A (en) 1990-06-22 1991-06-18 American Home Products Corporation Palatable ibuprofen solutions
JPH0541602A (ja) 1991-08-06 1993-02-19 Fujitsu General Ltd 円偏波及び直線偏波共用一次放射器
GB9207990D0 (en) 1992-04-10 1992-05-27 Smithkline Beecham Plc Pharmaceutical composition
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IT1277741B1 (it) * 1995-12-28 1997-11-12 Dompe Spa Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici
AUPN969796A0 (en) 1996-05-07 1996-05-30 F.H. Faulding & Co. Limited Taste masked liquid suspensions
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JP5242543B2 (ja) * 2006-03-16 2013-07-24 ノバルティス アーゲー 味をマスキングした活性薬剤を含有する固体剤形
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Also Published As

Publication number Publication date
JP5242543B2 (ja) 2013-07-24
RU2437657C2 (ru) 2011-12-27
MX2008011823A (es) 2008-10-31
WO2007109057A2 (en) 2007-09-27
CA2643944A1 (en) 2007-09-27
CN101404990A (zh) 2009-04-08
CN101404990B (zh) 2012-04-25
ATE486593T1 (de) 2010-11-15
WO2007109057A3 (en) 2007-12-06
US8986735B2 (en) 2015-03-24
CA2643944C (en) 2013-11-26
US20070292515A1 (en) 2007-12-20
JP2009530291A (ja) 2009-08-27
RU2008140383A (ru) 2010-04-27
PT1998762E (pt) 2010-11-30
BRPI0709382A2 (pt) 2011-07-12
AU2007227614A1 (en) 2007-09-27
ES2355306T3 (es) 2011-03-24
EP1998762A2 (de) 2008-12-10
EP1998762B1 (de) 2010-11-03
US20150157717A1 (en) 2015-06-11
PL1998762T3 (pl) 2011-04-29
AU2007227614B2 (en) 2011-01-06

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