DE602006006536D1 - Dry aripiprazole formulations - Google Patents

Dry aripiprazole formulations

Info

Publication number
DE602006006536D1
DE602006006536D1 DE602006006536T DE602006006536T DE602006006536D1 DE 602006006536 D1 DE602006006536 D1 DE 602006006536D1 DE 602006006536 T DE602006006536 T DE 602006006536T DE 602006006536 T DE602006006536 T DE 602006006536T DE 602006006536 D1 DE602006006536 D1 DE 602006006536D1
Authority
DE
Germany
Prior art keywords
dry
aripiprazole formulations
dry aripiprazole
formulations
tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006006536T
Other languages
German (de)
Inventor
Julia Hrakovsky
Ruth Tenengauzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36617397&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602006006536(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of DE602006006536D1 publication Critical patent/DE602006006536D1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention encompasses dry compression pharmaceutical compositions of aripiprazole, methods of making tablets from the compositions, and tablets of the dry compression pharmaceutical composition.
DE602006006536T 2006-01-05 2006-03-14 Dry aripiprazole formulations Active DE602006006536D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75670706P 2006-01-05 2006-01-05

Publications (1)

Publication Number Publication Date
DE602006006536D1 true DE602006006536D1 (en) 2009-06-10

Family

ID=36617397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006006536T Active DE602006006536D1 (en) 2006-01-05 2006-03-14 Dry aripiprazole formulations

Country Status (14)

Country Link
US (2) US20070154545A1 (en)
EP (1) EP1808165B1 (en)
JP (1) JP2008531738A (en)
CN (1) CN101351193A (en)
AT (1) ATE429906T1 (en)
CA (1) CA2627695A1 (en)
DE (1) DE602006006536D1 (en)
DK (1) DK1808165T3 (en)
ES (1) ES2325219T3 (en)
HK (1) HK1104795A1 (en)
IL (1) IL190915A0 (en)
PL (1) PL1808165T3 (en)
PT (1) PT1808165E (en)
WO (1) WO2007081367A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200604349A2 (en) * 2006-08-15 2008-03-21 NOBEL İLAÇ SANAYii VE TiCARET A.Ş. Pharmaceutical compositions containing aripiprazole
GB0618879D0 (en) 2006-09-26 2006-11-01 Zysis Ltd Pharmaceutical compositions
WO2010079506A2 (en) * 2008-06-23 2010-07-15 Torrent Pharmaceuticals Ltd. Pharmaceutical composition of aripiprazole
WO2011032882A1 (en) 2009-09-15 2011-03-24 Ratiopharm Gmbh Orally disintegrating pharmaceutical dosage form containing aripiprazole
TR201000948A1 (en) * 2010-02-09 2011-08-22 Sanovel İlaç San.Ve Ti̇c.A.Ş. Aripiprazole formulations.
EP2645994B1 (en) * 2010-11-30 2017-11-01 WisTa Laboratories Ltd. Formulations comprising methylthioninium chloride
CN102850268B (en) * 2011-06-27 2015-07-15 上海中西制药有限公司 Aripiprazole I-type crystallite, aripiprazole solid preparation and preparation methods thereof
WO2013175508A2 (en) 2012-05-24 2013-11-28 Medreich Limited Stable pharmaceutical composition of aripiprazole
AR096131A1 (en) 2013-04-30 2015-12-09 Otsuka Pharma Co Ltd SOLID ORAL PREPARATION THAT INCLUDES ARIPIPRAZOL AND A METHOD TO PRODUCE A SOLID ORAL PREPARATION THAT INCLUDES ARIPIPRAZOL
JP2016204260A (en) * 2013-10-04 2016-12-08 日本曹達株式会社 Production method of tablet
EP3065700A1 (en) * 2013-11-07 2016-09-14 Synthon B.V. Orodispersible pharmaceutical compositions comprising aripiprazole
CN106943405B (en) * 2016-01-06 2021-04-06 上海中西制药有限公司 Aripiprazole preparation and preparation method thereof
WO2017204582A1 (en) * 2016-05-27 2017-11-30 Hanmi Pharm. Co., Ltd. Pharmaceutical composition comprising an amide derivative or a pharmaceutically acceptable salt thereof inhibiting growth of cancer cells and a stabilizer having low melting point
CN108014343A (en) * 2017-12-21 2018-05-11 孟斯琴 A kind of pharmaceutical composition for treating breast cancer and preparation method thereof
CN111213650A (en) * 2020-02-25 2020-06-02 晋江市老君日化有限责任公司 Preparation process of mosquito-repellent incense

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
MY129350A (en) * 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution
AR033485A1 (en) * 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd MEDICINAL SUBSTANCE OF ARIPIPRAZOL OF LOW HYGROSCOPICITY AND PROCESS FOR THE PREPARATION OF THE SAME
TWI324074B (en) * 2001-10-09 2010-05-01 Bristol Myers Squibb Co Flashmelt oral dosage formulation
JP2003238393A (en) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd Tablet with improved tableting property and method for producing the same
DE10224170A1 (en) * 2002-05-31 2003-12-11 Desitin Arzneimittel Gmbh Retarded release pharmaceutical composition, obtained without use of organic solvents or water by densifying mixture of active agent and retarding polymer in heated rollers
EP1606262A1 (en) * 2003-03-21 2005-12-21 Hetero Drugs Limited Novel crystalline forms of aripiprazole
US20060270683A1 (en) * 2003-04-25 2006-11-30 Lohray Braj B Polymorphs of aripiprazole
ES2315721T5 (en) * 2003-10-23 2012-08-24 Otsuka Pharmaceutical Co., Ltd. Formulation of sterile controlled-release injectable aripiprazole and procedure
WO2005058835A2 (en) * 2003-12-16 2005-06-30 Teva Pharmaceutical Industries Ltd. Methods of preparing aripiprazole crystalline forms
US7507823B2 (en) * 2004-05-06 2009-03-24 Bristol-Myers Squibb Company Process of making aripiprazole particles
EP1812397A1 (en) * 2004-11-18 2007-08-01 Synthon B.V. Process of making crystalline aripiprazole
WO2006053780A1 (en) * 2004-11-18 2006-05-26 Synthon B.V. Crystalline aripiprazole solvates
EP1686117A1 (en) * 2005-01-27 2006-08-02 Sandoz AG Polymorph and solvates of aripiprazole
EP1858514B1 (en) * 2005-03-17 2014-11-26 Synthon B.V. Pharmaceutical tablets of crystalline type ii aripiprazole
MX2007013986A (en) * 2005-05-13 2008-02-22 Lexicon Pharmaceuticals Inc Multicyclic compounds and methods of their use.
US20070014854A1 (en) * 2005-07-15 2007-01-18 Ilan Zalit Novel granulation process
US20070014864A1 (en) * 2005-07-15 2007-01-18 Teva Pharmaceutical Industries, Ltd. Novel pharmaceutical granulate
US20070014853A1 (en) * 2005-07-15 2007-01-18 Ilan Zalit Pharmaceutical dosage form containing novel pharmaceutical granulate
JP2009508859A (en) * 2005-09-15 2009-03-05 エラン ファーマ インターナショナル リミテッド Nanoparticulate aripiprazole formulation
EP1919453A2 (en) * 2005-12-22 2008-05-14 Teva Pharmaceutical Industries Ltd Processes for reducing particle size of aripiprazole
US20070148245A1 (en) * 2005-12-22 2007-06-28 Ilan Zalit Compressed solid dosage forms with drugs of low solubility and process for making the same
EP1880714A1 (en) * 2006-07-20 2008-01-23 Helm AG Amorphous Aripiprazole and Process for the Preparation thereof

Also Published As

Publication number Publication date
PL1808165T3 (en) 2009-09-30
US20070154545A1 (en) 2007-07-05
DK1808165T3 (en) 2009-08-03
PT1808165E (en) 2009-06-09
EP1808165B1 (en) 2009-04-29
ES2325219T3 (en) 2009-08-28
ATE429906T1 (en) 2009-05-15
IL190915A0 (en) 2008-11-03
CN101351193A (en) 2009-01-21
US20130344146A1 (en) 2013-12-26
CA2627695A1 (en) 2007-07-19
HK1104795A1 (en) 2008-01-25
JP2008531738A (en) 2008-08-14
EP1808165A1 (en) 2007-07-18
WO2007081367A1 (en) 2007-07-19

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Legal Events

Date Code Title Description
8363 Opposition against the patent