DE602005027213D1 - Neue imidazolidinderivate - Google Patents

Neue imidazolidinderivate

Info

Publication number: DE602005027213D1
Authority: DE; Germany
Prior art keywords: imidazolidine derivatives; new; new imidazolidine; alkyl group; independently selected
Prior art date: 2004-08-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

DE602005027213T

Other languages

English (en)

Inventor

Kazutaka Tachibana

Haruhiko Sato

Masateru Ohta

Mitsuaki Nakamura

Takuya Shiraishi

Ikuhiro Imaoka

Hitoshi Yoshino

Masahiro Nagamuta

Hiromitsu Kawata

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Chugai Pharmaceutical Co Ltd

Original Assignee

Chugai Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-03

Filing date

2005-08-03

Publication date

2011-05-12

2005-08-03 Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd

2011-05-12 Publication of DE602005027213D1 publication Critical patent/DE602005027213D1/de

Status Active legal-status Critical Current

2025-08-04 Anticipated expiration legal-status Critical

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom

DE602005027213T 2004-08-03 2005-08-03 Neue imidazolidinderivate Active DE602005027213D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2004227321		2004-08-03
PCT/JP2005/014195 WO2006013887A1 (ja)	2004-08-03	2005-08-03	新規イミダゾリジン誘導体

Publications (1)

Publication Number	Publication Date
DE602005027213D1 true DE602005027213D1 (de)	2011-05-12

Family

ID=35787168

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE602005027213T Active DE602005027213D1 (de)	2004-08-03	2005-08-03	Neue imidazolidinderivate

Country Status (7)

Country	Link
US (1)	US7803826B2 (de)
EP (1)	EP1775289B1 (de)
JP (1)	JP4912148B2 (de)
AT (1)	ATE503746T1 (de)
DE (1)	DE602005027213D1 (de)
TW (1)	TW200612920A (de)
WO (1)	WO2006013887A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE502298T1 (de) *	2003-12-19	2011-04-15	Univ California	Verfahren und materialien zur beurteilung von prostatakrebstherapien
AU2005232526B2 (en)	2004-02-24	2011-06-23	The Regents Of The University Of California	Methods and materials for assessing prostate cancer therapies and compounds
US20070004679A1 (en) *	2004-05-17	2007-01-04	Nathalie Schlienger	Androgen receptor modulators and methods of treating disease using the same
KR20070112775A (ko)	2005-01-10	2007-11-27	아카디아 파마슈티칼스 인코포레이티드	선택적인 안드로겐 수용체 조절자로서의 아미노페닐 유도체
US7709517B2 (en) *	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
ES2377667T3 (es) *	2006-02-10	2012-03-29	Janssen Pharmaceutica N.V.	Heterociclos de imidazol bicíclico o de tiadiazol útiles como moduladores selectivos de receptores de andrógenos
EP3412290B1 (de) *	2006-03-27	2021-03-03	The Regents of The University of California	Androgenrezeptor-modulator zur behandlung von prostatakrebs und androgenrezeptor-assoziierte erkrankungen
CN101460467B (zh) *	2006-03-29	2012-09-19	加利福尼亚大学董事会	二芳基硫代乙内酰脲化合物
RU2319491C1 (ru) *	2006-07-12	2008-03-20	Бадулин Николай Александрович	Противоопухолевая, антибактериальная и антивирусная фармацевтическая композиция (ее варианты)
JP5535925B2 (ja)	2007-10-26	2014-07-02	ザリージェンツオブザユニバーシティオブカリフォルニア	アンドロゲン受容体調節物質としてのジアリールヒダントイン化合物
FR2944524B1 (fr) *	2009-04-17	2012-11-30	Ipsen Pharma Sas	Derives d'imidazolidine-2,4-dione et leur utilisation comme medicament
JP5659232B2 (ja) *	2009-09-10	2015-01-28	トン、ヨウヂ	アンドロゲン受容体アンタゴニストおよびその使用
TW201111378A (en)	2009-09-11	2011-04-01	Bayer Schering Pharma Ag	Substituted (heteroarylmethyl) thiohydantoins
SI3124481T1 (en)	2010-02-16	2018-06-29	Aragon Pharmaceuticals, Inc.	Androgen receptor modulators and their use
CN103608333B (zh)	2011-03-10	2016-01-06	苏州开拓药业有限公司	雄激素受体拮抗剂及其用途
MY180834A (en)	2012-09-26	2020-12-10	Aragon Pharmaceuticals Inc	Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
JOP20200097A1 (ar)	2013-01-15	2017-06-16	Aragon Pharmaceuticals Inc	معدل مستقبل أندروجين واستخداماته
EP3319939A1 (de) *	2015-07-08	2018-05-16	CV6 Therapeutics (NI) Limited	Hydantoinhaltige desoxyuridin-triphosphatase-inhibitoren
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
AU2018351714A1 (en)	2017-10-16	2020-04-30	Aragon Pharmaceuticals, Inc.	Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5411981A (en)	1991-01-09	1995-05-02	Roussel Uclaf	Phenylimidazolidines having antiandrogenic activity
FR2693461B1 (fr)	1992-07-08	1994-09-02	Roussel Uclaf	Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5656651A (en)	1995-06-16	1997-08-12	Biophysica Inc.	Androgenic directed compositions
WO2004111012A1 (ja) *	2003-06-12	2004-12-23	Chugai Seiyaku Kabushiki Kaisha	イミダゾリジン誘導体

2005
- 2005-08-03 TW TW094126369A patent/TW200612920A/zh unknown
- 2005-08-03 DE DE602005027213T patent/DE602005027213D1/de active Active
- 2005-08-03 WO PCT/JP2005/014195 patent/WO2006013887A1/ja active Application Filing
- 2005-08-03 AT AT05768418T patent/ATE503746T1/de not_active IP Right Cessation
- 2005-08-03 JP JP2006531511A patent/JP4912148B2/ja not_active Expired - Fee Related
- 2005-08-03 US US11/659,369 patent/US7803826B2/en not_active Expired - Fee Related
- 2005-08-03 EP EP05768418A patent/EP1775289B1/de not_active Not-in-force

Also Published As

Publication number	Publication date
US7803826B2 (en)	2010-09-28
EP1775289B1 (de)	2011-03-30
EP1775289A1 (de)	2007-04-18
TW200612920A (en)	2006-05-01
EP1775289A4 (de)	2009-09-02
WO2006013887A1 (ja)	2006-02-09
ATE503746T1 (de)	2011-04-15
JP4912148B2 (ja)	2012-04-11
JPWO2006013887A1 (ja)	2008-05-01
US20070249697A1 (en)	2007-10-25

Publication	Publication Date	Title
ATE503746T1 (de)	2011-04-15	Neue imidazolidinderivate
ATE388958T1 (de)	2008-03-15	4'-c-substituierte 2-haloadenosinderivate
NO20071642L (no)	2007-06-01	N-Benzensulfonylsubstituerte anilino-pyrimidinanaloger
ATE338461T1 (de)	2006-09-15	Pyrazolpyrimidinfungizide
EA200601830A1 (ru)	2007-04-27	Ортозамещённые арильные или гетероарильные амидные соединения
DK1767535T3 (da)	2010-04-12	Syntese af epothiloner, mellemprodukter deraf, analoge og deres anvendelse
AR057914A1 (es)	2007-12-26	Compuestos organicos de azufre y su uso
WO2008108380A3 (en)	2009-04-16	Pyrrole compounds
NO20054787D0 (no)	2005-10-18	Indenderivater som farmasotiske midler
TW200720249A (en)	2007-06-01	Pyrrolidine compound
TW200744589A (en)	2007-12-16	Pharmaceutical composition
DE602004020730D1 (de)	2009-06-04	Pharmazeutisches verfahren und damit hergestellte verbindungen
MY138466A (en)	2009-06-30	Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders
ATE504592T1 (de)	2011-04-15	Trehaloseverbindung und arzneimittel mit der verbindung
DE602004014727D1 (de)	2008-08-14	Aminoalkoholderivate, pharmazeutische zusammensetzungen, die diese enthalten, und verwendung davon
FR2894579B1 (fr)	2008-01-18	Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique.
HK1130496A1 (en)	2009-12-31	3'-ethynylcytidine derivative 3'-
NO20053997D0 (no)	2005-08-29	Oligosaccharidderivat
DE60105618D1 (de)	2004-10-21	Dihydroporphyrinderivate und ihre verwendung
AR034313A1 (es)	2004-02-18	Utilizacion de derivados de piridoindolona para la preparacion de medicamentos
DE602004009306D1 (de)	2007-11-15	3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern
DE60239491D1 (de)	2011-04-28	Thiazolidindionderivate und diese enthaltende pharmazeutische zusammensetzung
DE60330038D1 (de)	2009-12-24	Neue alpha-ketoamidderivate und deren verwendung
MY142362A (en)	2010-11-30	Pharmaceutical composition for promoting angiogenesis
FR2870237B1 (fr)	2008-09-26	Derives arylpyrroliques, arylfulraniques et arylthiopheniques a action antitubuline, procede de preparation et utilisation en tant qu'antimitotique