DE602005017152D1 - Neue 2,6-diaminopyridin-3-on-derivate - Google Patents
Neue 2,6-diaminopyridin-3-on-derivateInfo
- Publication number
- DE602005017152D1 DE602005017152D1 DE602005017152T DE602005017152T DE602005017152D1 DE 602005017152 D1 DE602005017152 D1 DE 602005017152D1 DE 602005017152 T DE602005017152 T DE 602005017152T DE 602005017152 T DE602005017152 T DE 602005017152T DE 602005017152 D1 DE602005017152 D1 DE 602005017152D1
- Authority
- DE
- Germany
- Prior art keywords
- diaminopyridin
- derivatives
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Mobile Radio Communication Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58812204P | 2004-07-15 | 2004-07-15 | |
PCT/EP2005/007432 WO2006005548A1 (en) | 2004-07-15 | 2005-07-08 | Novel 2,6-diaminopyridine-3-one derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005017152D1 true DE602005017152D1 (de) | 2009-11-26 |
Family
ID=35385535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005017152T Active DE602005017152D1 (de) | 2004-07-15 | 2005-07-08 | Neue 2,6-diaminopyridin-3-on-derivate |
Country Status (16)
Country | Link |
---|---|
US (1) | US7423051B2 (de) |
EP (1) | EP1771420B1 (de) |
JP (1) | JP2008505955A (de) |
KR (1) | KR100853973B1 (de) |
CN (1) | CN1980893B (de) |
AR (1) | AR050427A1 (de) |
AT (1) | ATE445604T1 (de) |
AU (1) | AU2005261899A1 (de) |
BR (1) | BRPI0513366A (de) |
CA (1) | CA2573604A1 (de) |
DE (1) | DE602005017152D1 (de) |
ES (1) | ES2330765T3 (de) |
MX (1) | MX2007000574A (de) |
RU (1) | RU2385866C2 (de) |
TW (1) | TW200612929A (de) |
WO (1) | WO2006005548A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007137196A2 (en) * | 2006-05-19 | 2007-11-29 | Threshold Pharmaceuticals, Inc. | Tubulin binding anti cancer compounds and prodrugs thereof |
EP1900727A1 (de) * | 2006-08-30 | 2008-03-19 | Cellzome Ag | Aminopyridinderivate als Kinase-Inhibitoren |
US8017607B2 (en) | 2009-10-14 | 2011-09-13 | Hoffmann-La Roche Inc. | N-substituted-pyrrolidines as inhibitors of MDM2-P-53 interactions |
CN113004285B (zh) * | 2019-12-20 | 2024-05-14 | 苏州信诺维医药科技股份有限公司 | 杂环化合物及其药物组合物、制备方法、中间体和应用 |
WO2022166793A1 (zh) * | 2021-02-05 | 2022-08-11 | 上海齐鲁制药研究中心有限公司 | Cdk抑制剂 |
CN113117077B (zh) * | 2021-03-04 | 2022-08-09 | 西南民族大学 | 一种用于肿瘤联合治疗的铂基单原子纳米酶及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9815200A (pt) | 1997-10-27 | 2001-10-16 | Agouron Pharma | Composto, composição farmacêutica e método de tratamento de uma doença ou distúrbio mediado pela inibição de cdk4 ou um complexo de cdk4/ciclina |
US6262096B1 (en) | 1997-11-12 | 2001-07-17 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
AU5108000A (en) * | 1999-06-10 | 2001-01-02 | Yamanouchi Pharmaceutical Co., Ltd. | Novel nitrogen-contaiing heterocyclic derivatives or salts thereof |
AP2002002479A0 (en) | 1999-09-15 | 2002-06-30 | Warner Lambert Co | Pteridinones as kinase inhibitors. |
MXPA02003140A (es) | 1999-11-22 | 2002-09-30 | Warner Lambert Co | Quinazolinas y su uso para la inhibicion de las enzimas cinasa dependientes del ciclin. |
WO2001079198A1 (en) | 2000-04-18 | 2001-10-25 | Agouron Pharmaceuticals, Inc. | Pyrazoles for inhibiting protein kinase |
BRPI0407618A (pt) | 2003-02-21 | 2006-02-21 | Pfizer | derivados de tiazole amino substituidos com cicloalquilo contendo n e composições farmacêuticas para inibição da proliferação celular e métodos para a sua utilização |
MXPA06005628A (es) | 2003-11-19 | 2006-12-14 | Johnson & Johnson | Compuestos de piridinil metanona amino sustituidos utiles en el tratamiento de trastornos de quinasa. |
-
2005
- 2005-06-24 US US11/165,912 patent/US7423051B2/en not_active Expired - Fee Related
- 2005-07-08 KR KR1020077001011A patent/KR100853973B1/ko not_active IP Right Cessation
- 2005-07-08 CN CN2005800223776A patent/CN1980893B/zh not_active Expired - Fee Related
- 2005-07-08 EP EP05759728A patent/EP1771420B1/de not_active Not-in-force
- 2005-07-08 RU RU2007105558/04A patent/RU2385866C2/ru not_active IP Right Cessation
- 2005-07-08 DE DE602005017152T patent/DE602005017152D1/de active Active
- 2005-07-08 CA CA002573604A patent/CA2573604A1/en not_active Abandoned
- 2005-07-08 BR BRPI0513366-1A patent/BRPI0513366A/pt not_active IP Right Cessation
- 2005-07-08 ES ES05759728T patent/ES2330765T3/es active Active
- 2005-07-08 WO PCT/EP2005/007432 patent/WO2006005548A1/en active Application Filing
- 2005-07-08 MX MX2007000574A patent/MX2007000574A/es active IP Right Grant
- 2005-07-08 AT AT05759728T patent/ATE445604T1/de not_active IP Right Cessation
- 2005-07-08 AU AU2005261899A patent/AU2005261899A1/en not_active Abandoned
- 2005-07-08 JP JP2007520726A patent/JP2008505955A/ja active Pending
- 2005-07-13 AR ARP050102903A patent/AR050427A1/es unknown
- 2005-07-14 TW TW094123936A patent/TW200612929A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1771420A1 (de) | 2007-04-11 |
TW200612929A (en) | 2006-05-01 |
KR20070028539A (ko) | 2007-03-12 |
WO2006005548A1 (en) | 2006-01-19 |
AR050427A1 (es) | 2006-10-25 |
CA2573604A1 (en) | 2006-01-19 |
ATE445604T1 (de) | 2009-10-15 |
US20060014708A1 (en) | 2006-01-19 |
ES2330765T3 (es) | 2009-12-15 |
JP2008505955A (ja) | 2008-02-28 |
CN1980893A (zh) | 2007-06-13 |
US7423051B2 (en) | 2008-09-09 |
BRPI0513366A (pt) | 2008-05-06 |
CN1980893B (zh) | 2011-01-19 |
EP1771420B1 (de) | 2009-10-14 |
AU2005261899A1 (en) | 2006-01-19 |
MX2007000574A (es) | 2007-03-07 |
RU2007105558A (ru) | 2008-08-20 |
RU2385866C2 (ru) | 2010-04-10 |
KR100853973B1 (ko) | 2008-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |