DE602005015855D1 - Verfahren zur herstellung von immunogenen konjugaten - Google Patents
Verfahren zur herstellung von immunogenen konjugatenInfo
- Publication number
- DE602005015855D1 DE602005015855D1 DE602005015855T DE602005015855T DE602005015855D1 DE 602005015855 D1 DE602005015855 D1 DE 602005015855D1 DE 602005015855 T DE602005015855 T DE 602005015855T DE 602005015855 T DE602005015855 T DE 602005015855T DE 602005015855 D1 DE602005015855 D1 DE 602005015855D1
- Authority
- DE
- Germany
- Prior art keywords
- agent
- carrier
- hapten
- modified
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2004/017736 WO2005000884A1 (en) | 2003-06-05 | 2004-06-04 | Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli |
US11/005,851 US7625736B2 (en) | 2004-06-04 | 2004-12-06 | Methods for preparing immunogenic conjugates |
PCT/US2005/019678 WO2005117965A1 (en) | 2004-06-04 | 2005-06-03 | Methods for preparing immunogenic conjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005015855D1 true DE602005015855D1 (de) | 2009-09-17 |
Family
ID=35449202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005015855T Active DE602005015855D1 (de) | 2004-06-04 | 2005-06-03 | Verfahren zur herstellung von immunogenen konjugaten |
Country Status (3)
Country | Link |
---|---|
US (2) | US7625736B2 (de) |
AT (1) | ATE438410T1 (de) |
DE (1) | DE602005015855D1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6248334B1 (en) * | 1997-01-08 | 2001-06-19 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process |
US6858211B1 (en) | 1998-07-20 | 2005-02-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccines against Escherichia coli O157 infection |
US7527797B1 (en) * | 2000-09-01 | 2009-05-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Vibrio cholerae 0139 conjugate vaccines |
US7803386B2 (en) * | 2003-06-05 | 2010-09-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli |
AU2007259329A1 (en) | 2006-05-12 | 2007-12-21 | Farris, Darise | Anthrax compositions and methods of use and production |
US11052142B2 (en) | 2013-06-04 | 2021-07-06 | Petr G. Aparin | Modified endotoxic bacteria lipopolysaccharide (variants), combination of modified lipopolysaccharides (variants) and, containing same, a vaccine (variants) and a pharmaceutical composition (variants) |
EA031879B1 (ru) * | 2013-06-04 | 2019-03-29 | Пётр Геннадиевич Апарин | Модифицированный липополисахарид эндотоксичных бактерий (варианты), комбинация модифицированных липополисахаридов (варианты) и включающие их вакцина (варианты) и фармацевтическая композиция (варианты) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
DK163176C (da) | 1985-09-27 | 1992-06-22 | Schweiz Serum & Impfinst | Ugiftig konjugatvaccine mod infektioner af pseudomonas aeruginosa- og escherichia coli- bakterier, fremgangsmaade til fremstilling heraf og anvendelse af vaccinen |
US5066789A (en) * | 1988-09-30 | 1991-11-19 | Neorx Corporation | Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages |
FR2639559B1 (fr) * | 1988-11-29 | 1991-01-11 | Bull Sa | Appareil pour separer et recuperer des particules solides de revelateur transportees par un flux gazeux |
JP2003522806A (ja) | 2000-02-15 | 2003-07-29 | ジェンザイム、コーポレーション | 改良された薬物送達のための生体高分子の修飾 |
US6911535B2 (en) * | 2000-03-22 | 2005-06-28 | Solvlink Biosciences | Biomolecule/polymer conjugates |
US7803386B2 (en) | 2003-06-05 | 2010-09-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli |
-
2004
- 2004-12-06 US US11/005,851 patent/US7625736B2/en not_active Expired - Fee Related
-
2005
- 2005-06-03 DE DE602005015855T patent/DE602005015855D1/de active Active
- 2005-06-03 AT AT05758048T patent/ATE438410T1/de not_active IP Right Cessation
-
2009
- 2009-10-20 US US12/582,420 patent/US8481048B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20050271675A1 (en) | 2005-12-08 |
US20100040644A1 (en) | 2010-02-18 |
US8481048B2 (en) | 2013-07-09 |
US7625736B2 (en) | 2009-12-01 |
ATE438410T1 (de) | 2009-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |