DE602005007874D1 - Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden - Google Patents

Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Info

Publication number
DE602005007874D1
DE602005007874D1 DE602005007874T DE602005007874T DE602005007874D1 DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1 DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1
Authority
DE
Germany
Prior art keywords
present
encoding
reaction
decoding
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005007874T
Other languages
English (en)
Inventor
Kai Qin Lao
Mark T Reed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Publication of DE602005007874D1 publication Critical patent/DE602005007874D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602005007874T 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden Active DE602005007874D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US55616204P 2004-03-24 2004-03-24
US55616304P 2004-03-24 2004-03-24
US55622404P 2004-03-24 2004-03-24
US55615704P 2004-03-24 2004-03-24
US63068104P 2004-11-24 2004-11-24
PCT/US2005/009882 WO2005094532A2 (en) 2004-03-24 2005-03-24 Encoding and decoding reactions for determining target polynucleotides

Publications (1)

Publication Number Publication Date
DE602005007874D1 true DE602005007874D1 (de) 2008-08-14

Family

ID=35064420

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602005014453T Active DE602005014453D1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen
DE602005007874T Active DE602005007874D1 (de) 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE602005014453T Active DE602005014453D1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen

Country Status (6)

Country Link
US (2) US7604937B2 (de)
EP (3) EP1727913B8 (de)
JP (2) JP2007530051A (de)
AT (2) ATE399884T1 (de)
DE (2) DE602005014453D1 (de)
WO (2) WO2005094532A2 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1552001A4 (de) * 2002-09-19 2006-01-04 Applera Corp Verfahren und zusammensetzungen zum nachweis von zielen
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US7604937B2 (en) 2004-03-24 2009-10-20 Applied Biosystems, Llc Encoding and decoding reactions for determining target polynucleotides
WO2005108618A2 (en) * 2004-04-30 2005-11-17 Applera Corporation Methods and kits for methylation detection
WO2006076017A2 (en) * 2004-04-30 2006-07-20 Applera Corporation Methods and kits for identifying target nucleotides in mixed populations
US7575863B2 (en) 2004-05-28 2009-08-18 Applied Biosystems, Llc Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
WO2006005055A2 (en) * 2004-06-30 2006-01-12 Applera Corporation Methods reaction mixtures and kits for ligating polynucleotides
JP2008513028A (ja) * 2004-09-21 2008-05-01 アプレラ コーポレイション マイクロRNA(miRNA)の二色リアルタイム/エンドポイント定量化
WO2007011867A2 (en) * 2005-07-15 2007-01-25 Applera Corporation Fluid processing device and method
US7745122B2 (en) 2005-07-15 2010-06-29 Applied Biosystems, Llc Analyzing messenger RNA and micro RNA in the same reaction mixture
WO2007024914A2 (en) * 2005-08-22 2007-03-01 Applera Corporation Device and method for microfluidic control of a first fluid in contact with a second fluid, wherein the first and second fluids are immiscible
WO2007025281A2 (en) 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
JP2009536525A (ja) * 2006-05-10 2009-10-15 ディクステリティー ダイアグノーティクス 化学反応性オリゴヌクレオチドプローブを使用した核酸標的の検出
US8597938B2 (en) * 2007-10-12 2013-12-03 Qiagen Sciences Llc System for providing control reactions for real time RT-PCR
US9157116B2 (en) * 2008-02-08 2015-10-13 Fluidigm Corporation Combinatorial amplification and detection of nucleic acids
WO2010027870A2 (en) * 2008-08-26 2010-03-11 Fluidigm Corporation Assay methods for increased throughput of samples and/or targets
GB2467691A (en) 2008-09-05 2010-08-11 Aueon Inc Methods for stratifying and annotating cancer drug treatment options
JP5608998B2 (ja) * 2009-03-31 2014-10-22 東洋紡株式会社 保存安定性に優れた核酸増幅検出試薬キット
WO2010114599A1 (en) * 2009-04-01 2010-10-07 Dx Terity Diagnostics Inc. Chemical ligation dependent probe amplification (clpa)
EP2789694A1 (de) 2009-04-02 2014-10-15 Fluidigm Corporation Mikrofluidische Vorrichtung mit Reaktionsproduktrückgewinnungssystem
US8574864B2 (en) * 2009-11-05 2013-11-05 Epicentre Technologies Corporation Methods and kits for 3'-end-tagging of RNA
EP2510126B1 (de) * 2009-12-07 2017-08-09 Illumina, Inc. Indexierung mehrerer proben für multiplex-genotypisierung
WO2011100057A2 (en) * 2010-02-09 2011-08-18 Eugene Spier Methods and compositions for universal detection of nucleic acids
WO2012040387A1 (en) 2010-09-24 2012-03-29 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
WO2012054933A2 (en) * 2010-10-22 2012-04-26 Fluidigm Corporation Universal probe assay methods
US20120288857A1 (en) * 2011-02-03 2012-11-15 Fluidigm Corporation Multifunctional probe-primers
WO2012142003A2 (en) 2011-04-15 2012-10-18 Life Technologies Corporation Chemical ligation
SG194722A1 (en) 2011-05-09 2013-12-30 Fluidigm Corp Probe based nucleic acid detection
AU2012255121B2 (en) 2011-05-17 2017-03-09 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
EP2710172B1 (de) 2011-05-20 2017-03-29 Fluidigm Corporation Nukleinsäure-kodierungsreaktionen
US20140242587A1 (en) * 2011-10-03 2014-08-28 University Of Florida Research Foundation, Inc. Rapid and Reliable Detection of Infectious Agents
JP6141872B2 (ja) 2011-12-30 2017-06-07 ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション 狭帯域発光を有する蛍光性ポリマードット
WO2013106807A1 (en) 2012-01-13 2013-07-18 Curry John D Scalable characterization of nucleic acids by parallel sequencing
JP6255353B2 (ja) 2012-02-03 2017-12-27 カリフォルニア インスティチュート オブ テクノロジー 多重生化学アッセイにおける信号エンコードおよびデコード
WO2013123220A1 (en) 2012-02-14 2013-08-22 Cornell University Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions
WO2013177206A2 (en) 2012-05-21 2013-11-28 Fluidigm Corporation Single-particle analysis of particle populations
CN104662172B (zh) 2012-08-03 2018-07-06 加州理工学院 Pcr中具有减少的硬件和要求的多重化和定量
EP2971172B1 (de) 2013-03-14 2019-07-24 Cornell University Verfahren zur relativen quantifizierung von veränderungen in einer dna-methylierung mit kombinierten nuklease-, ligations- und polymerasereaktionen
PT3126523T (pt) 2014-04-01 2020-05-15 Univ Cornell Deteção da metilação de adn utilizando reações de ligação e nuclease combinadas
JP6695285B2 (ja) 2014-06-10 2020-05-20 ディクステリティー ダイアグノスティクス インコーポレイテッド 生物学的試料を採取して安定化するためのデバイス及び方法
CN107002145B (zh) 2014-10-08 2021-07-30 康奈尔大学 一种用于鉴定样品中的含有靶核苷酸序列的一个或多个核酸分子的方法
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
CN108603224B (zh) 2015-12-16 2022-06-28 富鲁达公司 高水平多路复用扩增
CN108026568A (zh) * 2016-01-31 2018-05-11 阿费梅特里克斯公司 通过结合条形码标记的多核苷酸探针进行核酸分析
EP3472354A4 (de) 2016-06-17 2020-01-01 California Institute of Technology Nukleinsäurereaktionen sowie zugehörige verfahren und zusammensetzungen

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
EP0636186B1 (de) 1992-04-03 1998-11-25 The Perkin-Elmer Corporation Proben zusammensetzung und verfahren
WO1996015271A1 (en) 1994-11-16 1996-05-23 Abbott Laboratories Multiplex ligations-dependent amplification
GB9609441D0 (en) 1996-05-04 1996-07-10 Zeneca Ltd Process
AU730633B2 (en) 1996-05-29 2001-03-08 Phillip Belgrader Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US7014994B1 (en) * 1999-03-19 2006-03-21 Cornell Research Foundation,Inc. Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
CA2398107C (en) 2000-01-28 2013-11-19 Althea Technologies, Inc. Methods for analysis of gene expression
JP2004507226A (ja) * 2000-05-30 2004-03-11 ピーイー コーポレイション (エヌワイ) ライゲーションおよび増幅の組み合わせを用いて標的核酸を検出するための方法
US6620586B2 (en) 2001-02-20 2003-09-16 Applied Gene Technologies, Inc. Methods and compositions for analyzing nucleic acids
US20030119004A1 (en) 2001-12-05 2003-06-26 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
EP1319718A1 (de) 2001-12-14 2003-06-18 Keygene N.V. Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen
US20060088826A1 (en) * 2001-12-28 2006-04-27 Van Eijk Michael Josephus Ther Discrimination and detection of target nucleotide sequences using mass spectrometry
US6960436B2 (en) * 2002-02-06 2005-11-01 Epigenomics Ag Quantitative methylation detection in DNA samples
US7176002B2 (en) * 2002-05-16 2007-02-13 Applera Corporation Universal-tagged oligonucleotide primers and methods of use
EP1552001A4 (de) 2002-09-19 2006-01-04 Applera Corp Verfahren und zusammensetzungen zum nachweis von zielen
US20040214196A1 (en) 2002-09-19 2004-10-28 Applera Corporation Methods and compositions for detecting targets
US20040235005A1 (en) 2002-10-23 2004-11-25 Ernest Friedlander Methods and composition for detecting targets
US20040110134A1 (en) 2002-12-05 2004-06-10 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
WO2005026389A2 (en) 2003-08-29 2005-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
US7604937B2 (en) 2004-03-24 2009-10-20 Applied Biosystems, Llc Encoding and decoding reactions for determining target polynucleotides

Also Published As

Publication number Publication date
US20050272071A1 (en) 2005-12-08
WO2005094532A2 (en) 2005-10-13
EP1730312A2 (de) 2006-12-13
WO2005098040A2 (en) 2005-10-20
ATE431433T1 (de) 2009-05-15
EP2161346A1 (de) 2010-03-10
EP1727913A2 (de) 2006-12-06
US7604937B2 (en) 2009-10-20
US7601821B2 (en) 2009-10-13
WO2005098040A8 (en) 2005-12-01
EP1730312B1 (de) 2008-07-02
WO2005098040A3 (en) 2006-03-23
ATE399884T1 (de) 2008-07-15
JP2007530051A (ja) 2007-11-01
JP2007530048A (ja) 2007-11-01
WO2005094532A3 (en) 2005-12-22
EP1727913B8 (de) 2009-08-19
EP2161346B1 (de) 2013-06-19
EP1727913B1 (de) 2009-05-13
DE602005014453D1 (de) 2009-06-25
US20050260640A1 (en) 2005-11-24

Similar Documents

Publication Publication Date Title
ATE399884T1 (de) Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden
DE60133111D1 (de) Verfahren zur erkennung und zum assay von nukleinsäuresequenzen
WO2006019407A3 (en) Method for detecting and quantifying rare mutations/polymorphisms
WO2005094532B1 (en) Encoding and decoding reactions for determining target polynucleotides
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
Lee et al. Single-molecule visualization of ROS-induced DNA damage in large DNA molecules
DE50015854D1 (de) Oligonukleotide zur schnellen Bestimmung von mikrobieller DNS/RNS
WO2004044549A3 (en) Universal tag assay
WO2005047543A3 (en) Ligation assay
ATE414096T1 (de) Verfahren zum nachweis und zur quantifizierung von analyten in komplexen mischungen
ATE226983T1 (de) Gekoppeltes ampflikation- und ligationverfahren
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
WO2005010199A3 (en) Invasive cleavage reaction with electrochemical readout
DE69937447D1 (de) Verfahren zur erkennung von nukleinsäuren
WO2002083839A3 (en) P450 single nucleotide polymorphism biochip analysis
GB2539675A (en) Reagents, kits and methods for molecular barcoding
Cho et al. Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method
DE59914868D1 (de) DNA-Nachweis über einen Strangreassoziationskomplex
RU2016106961A (ru) Цифровой анализ молекулярных анализируемых веществ с помощью электрических способов
WO2008068636A3 (en) Blocking agents comprising non-natural nucleic acids and detection methods using such blocking agents
ATE290692T1 (de) Verfahren zur erkennung von verbindungen,die die wechselwirkung von rna und rna-bindungsproteinen beinflussen
DE502005010036D1 (de) Verfahren zur geno- und pathotypisierung von pseudomonas aeruginosa
Krieg et al. Fast Detection of Single Nucleotide Polymorphisms (SNPs) by Primer Elongation with Monitoring of Supercritical‐Angle Fluorescence
JPWO2020072829A5 (de)
JP5378724B2 (ja) 発現mRNA識別方法

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

Free format text: PFANDRECHT AUFGEHOBEN