DE602004022169D1 - Tetrahydrocarbazolderivate und deren pharmazeutische verwendung - Google Patents

Tetrahydrocarbazolderivate und deren pharmazeutische verwendung

Info

Publication number
DE602004022169D1
DE602004022169D1 DE602004022169T DE602004022169T DE602004022169D1 DE 602004022169 D1 DE602004022169 D1 DE 602004022169D1 DE 602004022169 T DE602004022169 T DE 602004022169T DE 602004022169 T DE602004022169 T DE 602004022169T DE 602004022169 D1 DE602004022169 D1 DE 602004022169D1
Authority
DE
Germany
Prior art keywords
tetrahydrocarbazol
derivatives
pharmaceutical use
pharmaceutical
tetrahydrocarbazol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004022169T
Other languages
English (en)
Inventor
Sharon Davis Boggs
Kristjan Gudmundsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of DE602004022169D1 publication Critical patent/DE602004022169D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE602004022169T 2003-06-12 2004-06-07 Tetrahydrocarbazolderivate und deren pharmazeutische verwendung Expired - Lifetime DE602004022169D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47797203P 2003-06-12 2003-06-12
US49778703P 2003-08-26 2003-08-26
PCT/US2004/018180 WO2005005386A1 (en) 2003-06-12 2004-06-07 Tetrahydrocarbazole derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
DE602004022169D1 true DE602004022169D1 (de) 2009-09-03

Family

ID=34068099

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004022169T Expired - Lifetime DE602004022169D1 (de) 2003-06-12 2004-06-07 Tetrahydrocarbazolderivate und deren pharmazeutische verwendung

Country Status (15)

Country Link
US (1) US7419997B2 (de)
EP (1) EP1646610B1 (de)
JP (1) JP2007500750A (de)
KR (1) KR20060017544A (de)
AU (1) AU2004256052A1 (de)
BR (1) BRPI0411245A (de)
CA (1) CA2528336A1 (de)
CO (1) CO5660264A2 (de)
DE (1) DE602004022169D1 (de)
ES (1) ES2327416T3 (de)
IL (1) IL172087A0 (de)
MA (1) MA27879A1 (de)
NO (1) NO20055750L (de)
RU (1) RU2005138126A (de)
WO (1) WO2005005386A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1678137A1 (de) * 2003-10-15 2006-07-12 Chiron Corporation Zusammensetzungen und verfahren zur inhibierung von viren
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
CA2559408C (en) 2004-03-15 2014-05-13 Ptc Therapeutics, Inc. Carboline derivatives useful in the inhibition of angiogenesis
WO2006012310A2 (en) * 2004-06-25 2006-02-02 Genzyme Corporation Carbazole derivatives for treating polycystic kidney disease
US20090170906A1 (en) * 2004-11-22 2009-07-02 Kristjan Gudmundsson Hcv inhibitors
MX2007006178A (es) 2004-11-23 2007-06-20 Ptc Therapeutics Inc Fenoles substituidos como agentes activos que inhiben la produccion del factor de crecimiento endotelial vascular.
WO2019005841A1 (en) * 2017-06-26 2019-01-03 Rutgers, The State University Of New Jersey THERAPEUTIC COMPOUNDS AND METHODS FOR TREATING INFECTION
US10882821B1 (en) 2017-09-26 2021-01-05 The Board Of Trustees Of The Leland Stanford Junior University Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008108D0 (en) 1990-04-10 1990-06-06 Bayer Ag Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
GB0015904D0 (en) * 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
DE10164564B4 (de) 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)

Also Published As

Publication number Publication date
NO20055750L (no) 2006-01-06
MA27879A1 (fr) 2006-05-02
ES2327416T3 (es) 2009-10-29
CA2528336A1 (en) 2005-01-20
WO2005005386A1 (en) 2005-01-20
US7419997B2 (en) 2008-09-02
BRPI0411245A (pt) 2006-07-18
KR20060017544A (ko) 2006-02-23
RU2005138126A (ru) 2006-07-27
CO5660264A2 (es) 2006-07-31
JP2007500750A (ja) 2007-01-18
IL172087A0 (en) 2009-02-11
NO20055750D0 (no) 2005-12-05
EP1646610B1 (de) 2009-07-22
US20060148857A1 (en) 2006-07-06
AU2004256052A1 (en) 2005-01-20
EP1646610A1 (de) 2006-04-19

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