DE602004015989D1 - Methode zur analyse phosphorylierter stellen und selektives markierungsmittel - Google Patents

Methode zur analyse phosphorylierter stellen und selektives markierungsmittel

Info

Publication number
DE602004015989D1
DE602004015989D1 DE602004015989T DE602004015989T DE602004015989D1 DE 602004015989 D1 DE602004015989 D1 DE 602004015989D1 DE 602004015989 T DE602004015989 T DE 602004015989T DE 602004015989 T DE602004015989 T DE 602004015989T DE 602004015989 D1 DE602004015989 D1 DE 602004015989D1
Authority
DE
Germany
Prior art keywords
phosphorylated
group
protected
stations
analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004015989T
Other languages
English (en)
Inventor
Yeong Hee Ahn
Jong Shin Yoo
Jin Young Kim
Kun Cho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Basic Science Institute KBSI
Original Assignee
Korea Basic Science Institute KBSI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Basic Science Institute KBSI filed Critical Korea Basic Science Institute KBSI
Publication of DE602004015989D1 publication Critical patent/DE602004015989D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602004015989T 2004-02-10 2004-02-10 Methode zur analyse phosphorylierter stellen und selektives markierungsmittel Expired - Lifetime DE602004015989D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2004/000256 WO2005075993A1 (en) 2004-02-10 2004-02-10 Selective labeling agent for phosphoproteome analysis and phosphorylated site analysis

Publications (1)

Publication Number Publication Date
DE602004015989D1 true DE602004015989D1 (de) 2008-10-02

Family

ID=34836659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015989T Expired - Lifetime DE602004015989D1 (de) 2004-02-10 2004-02-10 Methode zur analyse phosphorylierter stellen und selektives markierungsmittel

Country Status (6)

Country Link
US (1) US7250266B2 (de)
EP (1) EP1642129B1 (de)
JP (1) JP4271687B2 (de)
AT (1) ATE405831T1 (de)
DE (1) DE602004015989D1 (de)
WO (1) WO2005075993A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1799278A2 (de) * 2004-09-28 2007-06-27 Baylor University Räumlich definierte modifikation frischen gewebes mithilfe kovalenter chemie
KR100805775B1 (ko) 2005-08-08 2008-02-21 한국기초과학지원연구원 변형된 폴리펩티드(Ｍｏｄｉｆｉｅｄｐｏｌｙｐｅｐｔｉｄｅ)의 서열 및 변형 정보를 분석하는방법
DK1991273T4 (da) * 2006-02-10 2022-02-07 Life Technologies Corp Mærkning og påvisning af post-translationelt modificerede proteiner
US8859734B2 (en) * 2006-09-29 2014-10-14 Intel Corporation Method for the selective enrichment and labeling of phosphorproteins
CN103502818B (zh) 2011-02-16 2016-08-10 创革医疗科技有限公司 丝氨酸、苏氨酸的翻译后修饰解析用标记剂
US9328275B2 (en) 2014-03-07 2016-05-03 Prc Desoto International, Inc. Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions
KR101675303B1 (ko) * 2014-08-19 2016-11-11 한국표준과학연구원 마이크로 중공사막 효소 반응기-텐덤 질량분석법을 이용한 단세포군 항체 기반 온라인 인단백질 프로테오믹스 분석방법
US10814036B2 (en) 2016-11-07 2020-10-27 Baylor University Drug-eluting live tissue for transplantation
CN110609078B (zh) * 2019-09-20 2022-03-11 南京谱利健生物技术有限公司 一种检测蛋白磷酸化和乙酰氨基葡萄糖化关联作用的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344456T1 (de) * 2000-05-05 2006-11-15 Purdue Research Foundation Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
JP4141834B2 (ja) * 2000-10-23 2008-08-27 ジェネティックス インスティテュート エルエルシー マトリックス支援レーザー脱離イオン化マススペクトロメトリーを使用したハイスループットなタンパク質の同定及び定量のための同位体コードイオン化増強試薬（ｉｃｉｅｒ）
US6818454B2 (en) * 2001-02-16 2004-11-16 Battelle Memorial Institute Phosphoprotein binding agents and methods of their use
US20030017507A1 (en) * 2001-05-30 2003-01-23 Johnson Richard S. Relative protein quantitation phosphoproteins using stable isotope labeling
JP4163103B2 (ja) * 2001-06-07 2008-10-08 エレクトロフォレティクス リミテッド ポリペプチドの特徴分析方法
US7425451B2 (en) * 2002-12-13 2008-09-16 Agilent Technologies, Inc. Triazine derivatives as universal peptide isotope tag reagents (U-PIT)

Also Published As

Publication number Publication date
US20050176093A1 (en) 2005-08-11
WO2005075993A1 (en) 2005-08-18
ATE405831T1 (de) 2008-09-15
JP2006515674A (ja) 2006-06-01
EP1642129A1 (de) 2006-04-05
JP4271687B2 (ja) 2009-06-03
EP1642129A4 (de) 2006-07-26
EP1642129B1 (de) 2008-08-20
US7250266B2 (en) 2007-07-31

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