DE602004011235D1 - Verfahren zur gewinnung von urethangeschützten n-carboxyanhydriden von alpha-aminosäuren - Google Patents
Verfahren zur gewinnung von urethangeschützten n-carboxyanhydriden von alpha-aminosäurenInfo
- Publication number
- DE602004011235D1 DE602004011235D1 DE602004011235T DE602004011235T DE602004011235D1 DE 602004011235 D1 DE602004011235 D1 DE 602004011235D1 DE 602004011235 T DE602004011235 T DE 602004011235T DE 602004011235 T DE602004011235 T DE 602004011235T DE 602004011235 D1 DE602004011235 D1 DE 602004011235D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha
- protected
- carboxyanhydrides
- aminoacids
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001371 alpha-amino acids Chemical class 0.000 title abstract 7
- 235000008206 alpha-amino acids Nutrition 0.000 title abstract 6
- IMNIMPAHZVJRPE-UHFFFAOYSA-N triethylenediamine Chemical compound C1CN2CCN1CC2 IMNIMPAHZVJRPE-UHFFFAOYSA-N 0.000 abstract 6
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 230000003197 catalytic effect Effects 0.000 abstract 2
- ZFTFAPZRGNKQPU-UHFFFAOYSA-N dicarbonic acid Chemical class OC(=O)OC(O)=O ZFTFAPZRGNKQPU-UHFFFAOYSA-N 0.000 abstract 2
- 230000008018 melting Effects 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0310101 | 2003-08-22 | ||
| FR0310101A FR2858976B1 (fr) | 2003-08-22 | 2003-08-22 | Procede d'obtention de n-carboxyanhydrides d'alpha-aminoacides a protection urethane |
| PCT/FR2004/002148 WO2005021517A1 (fr) | 2003-08-22 | 2004-08-17 | Procede d’obtention de n-carboxyanhydrides d’alpha-aminoacides a protection urethane |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004011235D1 true DE602004011235D1 (de) | 2008-02-21 |
| DE602004011235T2 DE602004011235T2 (de) | 2009-01-02 |
Family
ID=34112854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004011235T Active DE602004011235T2 (de) | 2003-08-22 | 2004-08-17 | Verfahren zur gewinnung von urethangeschützten n-carboxyanhydriden von alpha-aminosäuren |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7667051B2 (de) |
| EP (1) | EP1660466B1 (de) |
| JP (1) | JP2007503419A (de) |
| KR (1) | KR20060120590A (de) |
| CN (1) | CN1839123A (de) |
| AT (1) | ATE383348T1 (de) |
| CA (1) | CA2536308A1 (de) |
| DE (1) | DE602004011235T2 (de) |
| DK (1) | DK1660466T3 (de) |
| ES (1) | ES2298827T3 (de) |
| FR (1) | FR2858976B1 (de) |
| MX (1) | MXPA06002113A (de) |
| WO (1) | WO2005021517A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8474853B2 (en) | 2006-11-28 | 2013-07-02 | G3 Genuine Guide Gear Inc. | Apparatus for attaching climbing skins |
| FR2913978B1 (fr) * | 2007-03-21 | 2009-07-03 | Centre Nat Rech Scient | Procede de synthese de peptides sans solvant |
| FR2928372B1 (fr) * | 2008-03-10 | 2010-12-31 | Solvay | Procede de synthese peptidique |
| CN110988246B (zh) * | 2019-11-29 | 2022-03-08 | 荆门医药工业技术研究院 | 一种检测z-l-缬氨酸及其中间体(s)-4-异丙基恶唑-2,5-二酮含量的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946942A (en) * | 1988-03-11 | 1990-08-07 | Bioresearch, Inc. | Urethane-protected amino acid-N-carboxyanhydrides |
| US5028693A (en) * | 1988-03-11 | 1991-07-02 | Bioresearch, Inc. | Urethane-protected amino acid-N-carboxyanhydrides |
| EP0492254B1 (de) * | 1990-12-20 | 1999-03-17 | Siemens Aktiengesellschaft | Verfahren zur Herstellung von N-tert.-Butoxycarbonyl-maleinimid |
| GB9604669D0 (en) * | 1996-03-05 | 1996-05-01 | Ciba Geigy Ag | Chemical compounds |
| ATE290564T1 (de) * | 1999-06-17 | 2005-03-15 | Univ Gent | Funktionsfähige poly-alpha-aminosäurederivate zur modifizierung von biologisch wirksamen stoffen und deren herstellung |
-
2003
- 2003-08-22 FR FR0310101A patent/FR2858976B1/fr not_active Expired - Fee Related
-
2004
- 2004-08-17 KR KR1020067003457A patent/KR20060120590A/ko not_active Application Discontinuation
- 2004-08-17 DE DE602004011235T patent/DE602004011235T2/de active Active
- 2004-08-17 DK DK04786315T patent/DK1660466T3/da active
- 2004-08-17 MX MXPA06002113A patent/MXPA06002113A/es unknown
- 2004-08-17 AT AT04786315T patent/ATE383348T1/de not_active IP Right Cessation
- 2004-08-17 US US10/569,320 patent/US7667051B2/en not_active Expired - Fee Related
- 2004-08-17 JP JP2006524387A patent/JP2007503419A/ja active Pending
- 2004-08-17 WO PCT/FR2004/002148 patent/WO2005021517A1/fr active IP Right Grant
- 2004-08-17 ES ES04786315T patent/ES2298827T3/es active Active
- 2004-08-17 CA CA002536308A patent/CA2536308A1/fr not_active Abandoned
- 2004-08-17 CN CNA2004800241572A patent/CN1839123A/zh active Pending
- 2004-08-17 EP EP04786315A patent/EP1660466B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP1660466B1 (de) | 2008-01-09 |
| US7667051B2 (en) | 2010-02-23 |
| FR2858976B1 (fr) | 2006-02-10 |
| KR20060120590A (ko) | 2006-11-27 |
| FR2858976A1 (fr) | 2005-02-25 |
| CN1839123A (zh) | 2006-09-27 |
| DK1660466T3 (da) | 2008-05-05 |
| ES2298827T3 (es) | 2008-05-16 |
| CA2536308A1 (fr) | 2005-03-10 |
| JP2007503419A (ja) | 2007-02-22 |
| WO2005021517A1 (fr) | 2005-03-10 |
| EP1660466A1 (de) | 2006-05-31 |
| US20060287534A1 (en) | 2006-12-21 |
| ATE383348T1 (de) | 2008-01-15 |
| DE602004011235T2 (de) | 2009-01-02 |
| MXPA06002113A (es) | 2006-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |