DE602004002464D1 - IMIDAZOi4,5-BöCHINOLINDERIVATE UND IHRE VERWENDUNG ALS INHIBITOREN DER INDUZIERBAREN NO-SYNTHASE - Google Patents

IMIDAZOi4,5-BöCHINOLINDERIVATE UND IHRE VERWENDUNG ALS INHIBITOREN DER INDUZIERBAREN NO-SYNTHASE

Info

Publication number
DE602004002464D1
DE602004002464D1 DE602004002464T DE602004002464T DE602004002464D1 DE 602004002464 D1 DE602004002464 D1 DE 602004002464D1 DE 602004002464 T DE602004002464 T DE 602004002464T DE 602004002464 T DE602004002464 T DE 602004002464T DE 602004002464 D1 DE602004002464 D1 DE 602004002464D1
Authority
DE
Germany
Prior art keywords
inhibitors
bochinoline
imidazoi4
synthase
inducible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602004002464T
Other languages
English (en)
Other versions
DE602004002464T2 (de
Inventor
Thomas Martin
Wolf-Ruediger Ulrich
Rainer Boer
Ulrich Graedler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of DE602004002464D1 publication Critical patent/DE602004002464D1/de
Application granted granted Critical
Publication of DE602004002464T2 publication Critical patent/DE602004002464T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE602004002464T 2003-02-25 2004-02-24 Imidazo[4,5-b]chinolinderivate und ihre Verwendung als Inhibitoren der induzierbaren NO-Synthase Expired - Fee Related DE602004002464T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03004102 2003-02-25
EP03004102 2003-02-25
PCT/EP2004/050201 WO2004076451A1 (en) 2003-02-25 2004-02-24 Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors

Publications (2)

Publication Number Publication Date
DE602004002464D1 true DE602004002464D1 (de) 2006-11-02
DE602004002464T2 DE602004002464T2 (de) 2007-10-04

Family

ID=32921577

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004002464T Expired - Fee Related DE602004002464T2 (de) 2003-02-25 2004-02-24 Imidazo[4,5-b]chinolinderivate und ihre Verwendung als Inhibitoren der induzierbaren NO-Synthase

Country Status (19)

Country Link
US (1) US7390819B2 (de)
EP (1) EP1599473B1 (de)
JP (1) JP2006518724A (de)
KR (1) KR20050107433A (de)
CN (1) CN1751043A (de)
AT (1) ATE340175T1 (de)
AU (1) AU2004215664A1 (de)
BR (1) BRPI0407573A (de)
CA (1) CA2516522A1 (de)
DE (1) DE602004002464T2 (de)
ES (1) ES2273225T3 (de)
HR (1) HRP20050799A8 (de)
IS (1) IS8034A (de)
MX (1) MXPA05008839A (de)
NO (1) NO20054289D0 (de)
PL (1) PL377613A1 (de)
RS (1) RS20050627A (de)
WO (1) WO2004076451A1 (de)
ZA (1) ZA200505725B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2328626T3 (es) * 2005-03-31 2009-11-16 Nycomed Gmbh Derivados de imidazopiridina utiles como inhibidores de inos.
WO2008031788A1 (en) * 2006-09-12 2008-03-20 Nycomed Gmbh Aminoazepine derivatives as highly efficient inhibitors of the inducible nitric oxide synthase
US8969349B2 (en) 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
ES8401486A1 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
ES2187775T3 (es) 1996-05-15 2003-06-16 Altana Pharma Ag Imidazopiridinas.

Also Published As

Publication number Publication date
BRPI0407573A (pt) 2006-02-14
ZA200505725B (en) 2006-05-31
ES2273225T3 (es) 2007-05-01
RS20050627A (en) 2007-09-21
NO20054289L (no) 2005-09-16
PL377613A1 (pl) 2006-02-06
NO20054289D0 (no) 2005-09-16
WO2004076451A1 (en) 2004-09-10
MXPA05008839A (es) 2005-10-05
KR20050107433A (ko) 2005-11-11
HRP20050799A2 (en) 2006-11-30
US7390819B2 (en) 2008-06-24
EP1599473B1 (de) 2006-09-20
EP1599473A1 (de) 2005-11-30
ATE340175T1 (de) 2006-10-15
HRP20050799A8 (en) 2007-10-31
IS8034A (is) 2005-09-16
US20060160839A1 (en) 2006-07-20
CA2516522A1 (en) 2004-09-10
DE602004002464T2 (de) 2007-10-04
CN1751043A (zh) 2006-03-22
AU2004215664A1 (en) 2004-09-10
JP2006518724A (ja) 2006-08-17

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee