DE60143892D1 - Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung - Google Patents
Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellungInfo
- Publication number
- DE60143892D1 DE60143892D1 DE60143892T DE60143892T DE60143892D1 DE 60143892 D1 DE60143892 D1 DE 60143892D1 DE 60143892 T DE60143892 T DE 60143892T DE 60143892 T DE60143892 T DE 60143892T DE 60143892 D1 DE60143892 D1 DE 60143892D1
- Authority
- DE
- Germany
- Prior art keywords
- similar
- heart
- manufacture
- cell layer
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2539/00—Supports and/or coatings for cell culture characterised by properties
- C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000221385 | 2000-07-21 | ||
PCT/JP2001/005722 WO2002008387A1 (fr) | 2000-07-21 | 2001-07-02 | Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60143892D1 true DE60143892D1 (de) | 2011-03-03 |
Family
ID=18715796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60143892T Expired - Lifetime DE60143892D1 (de) | 2000-07-21 | 2001-07-02 | Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040009566A1 (de) |
EP (2) | EP2275532B1 (de) |
JP (2) | JP4679795B2 (de) |
AT (1) | ATE495766T1 (de) |
DE (1) | DE60143892D1 (de) |
ES (2) | ES2385301T3 (de) |
WO (1) | WO2002008387A1 (de) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8889417B2 (en) | 2000-07-21 | 2014-11-18 | Cellseed Inc. | Epidermal cultured cell sheet, multi-layered cultured skin sheet and processes for producing those sheets |
DE60143892D1 (de) * | 2000-07-21 | 2011-03-03 | Cellseed Ind | Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung |
JP5226923B2 (ja) * | 2002-04-15 | 2013-07-03 | 株式会社セルシード | 心筋細胞シートによる心筋症治療薬 |
US7560276B2 (en) | 2003-06-27 | 2009-07-14 | Ethicon, Incorporated | Soft tissue repair and regeneration using postpartum-derived cells |
EP2267115B8 (de) * | 2003-02-06 | 2014-07-23 | Cellseed Inc. | Zellblatt des vorderen Augensegments, dreidimensionale Strukturen und Herstellungsverfahren dafür |
EP1600498B1 (de) * | 2003-02-06 | 2012-08-15 | Cellseed Inc. | Substraten für hochdichte-zellanordnungsleiterplatte, prozess zum herstellen und verfahren zum verwenden derselben |
ES2538696T3 (es) | 2003-02-06 | 2015-06-23 | Cellseed Inc. | Láminas de células para la formación de la ectocórnea, método para producir las mismas y método para usar las mismas |
WO2004073761A1 (ja) * | 2003-02-20 | 2004-09-02 | Cellseed Inc. | 再生角膜内皮細胞シート、製造方法及びその利用方法 |
JP4756816B2 (ja) * | 2003-03-10 | 2011-08-24 | 株式会社アドバンス | 骨再生補綴物の製造方法 |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
WO2005011808A1 (en) * | 2003-07-28 | 2005-02-10 | Medtronic, Inc. | Myocardial stimulation |
JP4943844B2 (ja) * | 2003-08-01 | 2012-05-30 | 株式会社セルシード | 三次元組織構造体 |
EP1748064B1 (de) * | 2004-04-25 | 2019-04-17 | CellSeed Inc. | Kultivierte Periodontalverbindungzellage, Herstellungsverfahren sowie Verwendung davon |
JP4303643B2 (ja) | 2004-06-01 | 2009-07-29 | 育男 森田 | 人工組織体およびその製造方法 |
GB0425266D0 (en) * | 2004-11-16 | 2004-12-15 | Norton Healthcare Ltd | Pharmaceutical manufacturing process |
US20060166361A1 (en) * | 2004-12-21 | 2006-07-27 | Agnieszka Seyda | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
US20060171930A1 (en) * | 2004-12-21 | 2006-08-03 | Agnieszka Seyda | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
ES2621847T3 (es) | 2004-12-23 | 2017-07-05 | DePuy Synthes Products, Inc. | Células posparto derivadas de tejido de cordón umbilical, y métodos de elaboración y uso de las mismas |
JP2006223106A (ja) * | 2005-02-15 | 2006-08-31 | Fuji Photo Film Co Ltd | 細胞培養担体 |
EP1859817A4 (de) | 2005-02-28 | 2012-11-07 | Cellseed Inc | Gezüchtete zellplatte, verfahren zu ihrer herstellung und verfahren zur wiederherstellung von gewebe unter verwendung der platte |
WO2006093151A1 (ja) * | 2005-02-28 | 2006-09-08 | Cellseed Inc. | 培養細胞シート、製造方法及びその利用方法 |
EP1728856B1 (de) | 2005-06-01 | 2009-05-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur optischen Bestimmung des dynamischen Verhaltens von kontrahierenden Zellen |
US9249386B2 (en) * | 2005-06-06 | 2016-02-02 | Dai Nippon Printing Co., Ltd. | Substrate for cell transfer |
WO2007050314A2 (en) * | 2005-10-24 | 2007-05-03 | Hosheng Tu | Medical device with living cell sheet |
US8492150B2 (en) * | 2006-02-03 | 2013-07-23 | President And Fellows Of Harvard College | Engineered cell growth on polymeric films and biotechnological applications thereof |
WO2008045506A2 (en) * | 2006-10-10 | 2008-04-17 | President And Fellows Of Harvard College | Biopolymer structures |
JP5424538B2 (ja) * | 2007-03-19 | 2014-02-26 | 株式会社セルシード | 移植用成熟誘導化樹状細胞、製造方法及びその利用方法 |
EP2626413B8 (de) | 2007-05-11 | 2016-07-20 | Dai Nippon Printing Co., Ltd. | Zellschicht mit guter dimensionaler Stabilität, Herstellungsverfahren dafür und Zellkulturträger zur Verwendung in diesem Verfahren |
US8202720B2 (en) * | 2007-06-08 | 2012-06-19 | Mitsubishi Chemical Medience Corporation | Model cell chip, apparatus for evaluating drug effect using the model cell chip and method of evaluating drug effect |
US9068168B2 (en) * | 2007-09-26 | 2015-06-30 | President And Fellows Of Harvard College | Boundary conditions for the arrangement of cells and tissues |
US8748181B2 (en) | 2008-05-23 | 2014-06-10 | President And Fellows Of Harvard College | Methods of generating patterned soft substrates and uses thereof |
EP2348099B1 (de) * | 2008-10-14 | 2017-07-05 | CellSeed Inc. | Temperaturreaktives zellkultursubstrat und verfahren zu seiner herstellung |
JP5614928B2 (ja) | 2008-12-05 | 2014-10-29 | 国立大学法人 東京医科歯科大学 | 心筋毒性検査装置、心筋毒性検査チップおよび心筋毒性検査方法 |
US20100166822A1 (en) * | 2008-12-31 | 2010-07-01 | Howmedica Osteonics Corp. | Adhesive cartilage implant |
JP5725560B2 (ja) | 2009-03-04 | 2015-05-27 | 学校法人東京女子医科大学 | 細胞シートを利用した細胞評価システム及びその利用方法 |
WO2010127280A1 (en) | 2009-05-01 | 2010-11-04 | President And Fellows Of Harvard College | High throughput assays for determining contractile function and devices for use therein |
WO2011058813A1 (ja) | 2009-11-13 | 2011-05-19 | Sawa Yoshiki | 心筋再生用細胞シート、製造方法及びその利用方法 |
US20120308533A1 (en) | 2009-12-03 | 2012-12-06 | Osaka University | Adipocyte sheet, three-dimensional structure thereof, and method for producing the same |
WO2012006320A1 (en) | 2010-07-06 | 2012-01-12 | President And Fellows Of Harvard College | Photosensitive cardiac rhythm modulation systems |
EP2617810B1 (de) | 2010-09-14 | 2016-04-13 | Tokyo Women's Medical University | Verfahren zur herstellung geschichteter zellschichten, geschichtete zellschichten mit einem dadurch gewonnenen gefässnetz sowie verfahren zu ihrer verwendung |
JP5322333B2 (ja) | 2010-09-14 | 2013-10-23 | 学校法人東京女子医科大学 | 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法 |
JP5367672B2 (ja) * | 2010-09-27 | 2013-12-11 | 株式会社セルシード | 心筋細胞シートによる心筋症治療薬 |
JP5370376B2 (ja) | 2011-01-13 | 2013-12-18 | 横河電機株式会社 | 機器情報表示装置、機器情報表示プログラム、及び記録媒体 |
JP5840855B2 (ja) | 2011-03-30 | 2016-01-06 | 学校法人東京女子医科大学 | 胚性幹細胞から心筋シートを製造する方法 |
JP5816452B2 (ja) | 2011-03-31 | 2015-11-18 | 株式会社セルシード | 細胞シート移植治具及びその利用方法 |
US9857356B2 (en) | 2011-12-09 | 2018-01-02 | President And Fellows Of Havard College | Muscle chips and methods of use thereof |
EP2826855B1 (de) | 2012-03-15 | 2018-08-29 | iHeart Japan Corporation | Myocardiale zellschicht |
JP5990403B2 (ja) * | 2012-05-31 | 2016-09-14 | 株式会社 ジャパン・ティッシュ・エンジニアリング | 培養皿及び培養キット |
WO2014015251A2 (en) | 2012-07-20 | 2014-01-23 | President And Fellows Of Harvard College | Tissue-engineered pumps and valves and uses thereof |
JP6301098B2 (ja) * | 2013-10-02 | 2018-03-28 | テルモ株式会社 | シート状細胞培養物の剥離方法および製造方法ならびにこれらに用いる容器 |
US10591458B2 (en) | 2014-02-18 | 2020-03-17 | President And Fellows Of Harvard College | Anisotropic muscular tissue devices with integrated electrical force readouts |
JP6459458B2 (ja) * | 2014-03-03 | 2019-01-30 | ソニー株式会社 | 細胞評価装置 |
JP6653437B2 (ja) | 2014-06-24 | 2020-02-26 | 薫 鷲尾 | インプラント培養歯根膜細胞シート複合体、その製造方法及びその利用方法 |
WO2016069142A2 (en) | 2014-09-24 | 2016-05-06 | President And Fellows Of Harvard College | Contractile function measuring devices, systems, and methods of use thereof |
WO2017087759A1 (en) | 2015-11-18 | 2017-05-26 | President And Fellows Of Harvard College | Cartridge-based system for long term culture of cell clusters |
JP2017140109A (ja) | 2016-02-08 | 2017-08-17 | テルモ株式会社 | 治療方法および医療用装置 |
EP4349972A3 (de) | 2016-02-22 | 2024-05-29 | Osaka University | Verfahren zur herstellung von dreidimensionalem zellgewebe |
JP7130198B2 (ja) * | 2017-06-29 | 2022-09-05 | 日本光電工業株式会社 | 積層化細胞シートの製造方法、及びそれにより作製される積層化細胞シート |
US11111611B2 (en) | 2017-06-30 | 2021-09-07 | Board Of Regents, The University Of Texas System | Electrospun PNIPAAm/PCL fiber mats for aligned cell sheets |
US11629318B2 (en) | 2017-10-20 | 2023-04-18 | President And Fellows Of Harvard College | Methods for producing mature adipocytes and methods of use thereof |
CN112657051B (zh) * | 2020-12-25 | 2023-08-04 | 上海交通大学医学院附属上海儿童医学中心 | 一种基于共轭同轴静电纺丝技术的生物型心室辅助泵及其制备方法 |
US20240124834A1 (en) | 2021-02-17 | 2024-04-18 | Fukuoka University | Cell sheet support, cell sheet laminate and method for producing same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4304866A (en) * | 1979-11-14 | 1981-12-08 | Massachusetts Institute Of Technology | Transplantable sheets of living keratinous tissue |
JP2549151B2 (ja) | 1988-07-13 | 1996-10-30 | 株式会社東芝 | マンコンベヤ |
JPH06104061B2 (ja) | 1989-02-10 | 1994-12-21 | 花王株式会社 | 細胞培養支持体材料 |
US5543318A (en) * | 1991-06-12 | 1996-08-06 | Smith; David A. | Method of isolation, culture and proliferation of human atrial myocytes |
JPH05192138A (ja) | 1992-01-22 | 1993-08-03 | Kao Corp | 皮膚細胞培養法及び培養皮膚 |
US6099832A (en) * | 1997-05-28 | 2000-08-08 | Genzyme Corporation | Transplants for myocardial scars |
JP2000023191A (ja) | 1998-06-30 | 2000-01-21 | Aqueous Reserch:Kk | 動画像圧縮装置 |
DE60143892D1 (de) * | 2000-07-21 | 2011-03-03 | Cellseed Ind | Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung |
-
2001
- 2001-07-02 DE DE60143892T patent/DE60143892D1/de not_active Expired - Lifetime
- 2001-07-02 EP EP10181984A patent/EP2275532B1/de not_active Expired - Lifetime
- 2001-07-02 EP EP01945762A patent/EP1302535B1/de not_active Expired - Lifetime
- 2001-07-02 US US10/333,473 patent/US20040009566A1/en not_active Abandoned
- 2001-07-02 JP JP2002513872A patent/JP4679795B2/ja not_active Expired - Fee Related
- 2001-07-02 ES ES10181984T patent/ES2385301T3/es not_active Expired - Lifetime
- 2001-07-02 WO PCT/JP2001/005722 patent/WO2002008387A1/ja active Application Filing
- 2001-07-02 ES ES01945762T patent/ES2357764T3/es not_active Expired - Lifetime
- 2001-07-02 AT AT01945762T patent/ATE495766T1/de not_active IP Right Cessation
-
2010
- 2010-07-27 JP JP2010168577A patent/JP5086398B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP5086398B2 (ja) | 2012-11-28 |
JP2011004750A (ja) | 2011-01-13 |
JP4679795B2 (ja) | 2011-04-27 |
JPWO2002008387A1 (ja) | 2004-02-05 |
ES2357764T3 (es) | 2011-04-29 |
WO2002008387A1 (fr) | 2002-01-31 |
ES2385301T3 (es) | 2012-07-20 |
EP2275532B1 (de) | 2012-06-06 |
EP1302535A1 (de) | 2003-04-16 |
US20040009566A1 (en) | 2004-01-15 |
EP1302535B1 (de) | 2011-01-19 |
EP2275532A1 (de) | 2011-01-19 |
EP1302535A4 (de) | 2007-08-29 |
ATE495766T1 (de) | 2011-02-15 |
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