DE60140960D1 - Verwendung von serp-1 in kombination mit einem immunosuppressor zur behandlung von arthritis - Google Patents
Verwendung von serp-1 in kombination mit einem immunosuppressor zur behandlung von arthritisInfo
- Publication number
- DE60140960D1 DE60140960D1 DE60140960T DE60140960T DE60140960D1 DE 60140960 D1 DE60140960 D1 DE 60140960D1 DE 60140960 T DE60140960 T DE 60140960T DE 60140960 T DE60140960 T DE 60140960T DE 60140960 D1 DE60140960 D1 DE 60140960D1
- Authority
- DE
- Germany
- Prior art keywords
- serp
- treatment
- combination
- immunosup
- pressor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23693900P | 2000-09-29 | 2000-09-29 | |
PCT/CA2001/001369 WO2002026245A2 (en) | 2000-09-29 | 2001-09-28 | Use of serp-1 in combination with an immunosuppressant for influencing inflammatory and immune reactions |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60140960D1 true DE60140960D1 (de) | 2010-02-11 |
Family
ID=22891637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60140960T Expired - Lifetime DE60140960D1 (de) | 2000-09-29 | 2001-09-28 | Verwendung von serp-1 in kombination mit einem immunosuppressor zur behandlung von arthritis |
Country Status (8)
Country | Link |
---|---|
US (1) | US7419670B2 (de) |
EP (1) | EP1365798B1 (de) |
JP (1) | JP2004509171A (de) |
AT (1) | ATE453402T1 (de) |
AU (2) | AU9157901A (de) |
CA (1) | CA2423313A1 (de) |
DE (1) | DE60140960D1 (de) |
WO (1) | WO2002026245A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2243314T3 (es) | 1999-10-27 | 2005-12-01 | Alexandra Lucas | Composiciones para la prevencion y el tratamiento del rechazo de trasplantes. |
AU9157901A (en) | 2000-09-29 | 2002-04-08 | Z Robert Zhong | Methods of treating inflammatory and immune reactions and compositions therefor |
WO2004039391A1 (en) * | 2002-11-01 | 2004-05-13 | Lucas Alexandra R | Viral serpin regulation of inflamation |
FR2849598B1 (fr) * | 2003-01-07 | 2006-09-22 | Merck Sante Sas | Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans |
US7285530B2 (en) | 2004-10-21 | 2007-10-23 | Viron Therapeutics, Inc. | Use of SERP-1 as an antiplatelet agent |
EP2023948A1 (de) * | 2006-05-04 | 2009-02-18 | Michel Ovize | Verwendung von cyclosporin a oder melle4-cyclosporin zur behandlung von akutem myokardinfarkt |
US8251876B2 (en) | 2008-04-22 | 2012-08-28 | Hill-Rom Services, Inc. | Breathing exercise apparatus |
US9518107B2 (en) | 2010-08-31 | 2016-12-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Pharmaceutical compositions containing polypeptides derived from α-1 antitrypsin and methods of use thereof |
US20130203650A1 (en) | 2010-08-31 | 2013-08-08 | Yissum Research Development Company Of The Hebrew Uviversity Of Jerusalem | Polypeptides derived from alpha-1 antitrypsin and methods of use thereof |
US20140050728A1 (en) * | 2011-01-28 | 2014-02-20 | Board Of Regents Of The University Of Nebraska | Methods and compositions for inhibiting cyclophilin d for the treatment and prevention of obesity and kidney indications |
US9180271B2 (en) | 2012-03-05 | 2015-11-10 | Hill-Rom Services Pte. Ltd. | Respiratory therapy device having standard and oscillatory PEP with nebulizer |
US10842763B2 (en) | 2015-07-31 | 2020-11-24 | The Johns Hopkins University | Methods for cancer and immunotherapy using prodrugs of glutamine analogs |
CN108290827B (zh) | 2015-07-31 | 2021-01-01 | 约翰霍普金斯大学 | 谷氨酰胺类似物的前药 |
EP3328375B1 (de) | 2015-07-31 | 2022-08-31 | The Johns Hopkins University | Verfahren für krebs und immuntherapie mit glutaminanaloga, einschliesslich don |
WO2018144718A1 (en) | 2017-02-01 | 2018-08-09 | The Johns Hopkins University | Prodrugs of glutamine analogs |
EP3911351A4 (de) * | 2019-01-14 | 2022-10-19 | Arizona Board of Regents on behalf of Arizona State University | Serinproteinasehemmer: wirkung von serp-1- und serp-1-rcl-derivierten peptiden auf mikrobiomzusammensetzung und deren verwendungen |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5206017A (en) | 1986-06-03 | 1993-04-27 | Incyte Pharmaceuticals, Inc. | Use of protease nexin-I as an antiinflammatory |
DE3829523A1 (de) | 1988-08-31 | 1990-03-01 | Behringwerke Ag | Verwendung von plasminogen-aktivator-inhibitor (pai-2) zur immunsuppression |
GB9007971D0 (en) | 1990-04-09 | 1990-06-06 | Imutran Ltd | Pharmaceutical formulations |
EP0512090B2 (de) | 1990-10-16 | 2006-11-22 | Sonoran Desert Chemicals LLC | Behandlung von entzündungen |
WO1992022320A1 (en) | 1991-06-14 | 1992-12-23 | Genentech, Inc. | C1 inhibitor variants and treating inflammatory response with c1 inhibitor |
DE4214215A1 (de) | 1992-04-30 | 1993-11-04 | Behringwerke Ag | Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen |
US5686409A (en) | 1994-04-08 | 1997-11-11 | Research Corporation Technologies, Inc. | Antirestenosis protein |
US5624946A (en) | 1994-07-05 | 1997-04-29 | Williams; James | Use of leflunomide to control and reverse chronic allograft rejection |
US5939525A (en) | 1995-03-27 | 1999-08-17 | Viron Therapeutics, Inc. | Methods of treating inflammation and compositions therefor |
AU7108496A (en) | 1995-09-11 | 1997-04-01 | Governors Of The University Of Alberta, The | Method for inhibiting cell-mediated killing of target cells |
GB9811854D0 (en) * | 1998-06-02 | 1998-07-29 | Ciba Geigy Ag | Organic compounds |
EP0982035B1 (de) | 1998-08-18 | 2004-03-31 | Panacea Biotec Limited | Zusammensetzung enthalten Cyclsoporin in einem hydrophilen Träger |
US20020006901A1 (en) | 1999-02-05 | 2002-01-17 | Aldo T. Iacono | Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease |
WO2000053793A1 (en) | 1999-03-10 | 2000-09-14 | Human Genome Sciences, Inc. | Brain-associated inhibitor of tissue-type plasminogen activator |
ES2243314T3 (es) | 1999-10-27 | 2005-12-01 | Alexandra Lucas | Composiciones para la prevencion y el tratamiento del rechazo de trasplantes. |
US6428308B1 (en) | 1999-11-29 | 2002-08-06 | Honeywell Inc. | Electronic fuel convertibility selection |
WO2001039790A1 (en) | 1999-12-02 | 2001-06-07 | Viron Therapeutics, Inc. | Methods of treating inflammation and compositions therefor |
AU9157901A (en) | 2000-09-29 | 2002-04-08 | Z Robert Zhong | Methods of treating inflammatory and immune reactions and compositions therefor |
WO2004039391A1 (en) | 2002-11-01 | 2004-05-13 | Lucas Alexandra R | Viral serpin regulation of inflamation |
US7285530B2 (en) | 2004-10-21 | 2007-10-23 | Viron Therapeutics, Inc. | Use of SERP-1 as an antiplatelet agent |
-
2001
- 2001-09-28 AU AU9157901A patent/AU9157901A/xx active Pending
- 2001-09-28 WO PCT/CA2001/001369 patent/WO2002026245A2/en active Application Filing
- 2001-09-28 CA CA002423313A patent/CA2423313A1/en not_active Abandoned
- 2001-09-28 AT AT01971584T patent/ATE453402T1/de not_active IP Right Cessation
- 2001-09-28 EP EP01971584A patent/EP1365798B1/de not_active Expired - Lifetime
- 2001-09-28 JP JP2002530075A patent/JP2004509171A/ja active Pending
- 2001-09-28 US US10/381,875 patent/US7419670B2/en not_active Expired - Fee Related
- 2001-09-28 AU AU2001291579A patent/AU2001291579B2/en not_active Ceased
- 2001-09-28 DE DE60140960T patent/DE60140960D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1365798A2 (de) | 2003-12-03 |
JP2004509171A (ja) | 2004-03-25 |
US7419670B2 (en) | 2008-09-02 |
AU2001291579B2 (en) | 2006-08-31 |
WO2002026245A2 (en) | 2002-04-04 |
CA2423313A1 (en) | 2002-04-04 |
US20040029801A1 (en) | 2004-02-12 |
WO2002026245A3 (en) | 2003-10-09 |
AU9157901A (en) | 2002-04-08 |
EP1365798B1 (de) | 2009-12-30 |
ATE453402T1 (de) | 2010-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |