DE60139399D1 - Gpr8 ligand und dafuer kodierende dna - Google Patents
Gpr8 ligand und dafuer kodierende dnaInfo
- Publication number
- DE60139399D1 DE60139399D1 DE60139399T DE60139399T DE60139399D1 DE 60139399 D1 DE60139399 D1 DE 60139399D1 DE 60139399 T DE60139399 T DE 60139399T DE 60139399 T DE60139399 T DE 60139399T DE 60139399 D1 DE60139399 D1 DE 60139399D1
- Authority
- DE
- Germany
- Prior art keywords
- gpr8
- dafuer
- ligand
- encoding dna
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101000603411 Homo sapiens Neuropeptides B/W receptor type 2 Proteins 0.000 title abstract 5
- 102100038843 Neuropeptides B/W receptor type 2 Human genes 0.000 title abstract 5
- 239000003446 ligand Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 1
- 102000003946 Prolactin Human genes 0.000 abstract 1
- 108010057464 Prolactin Proteins 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 239000002948 appetite stimulant Substances 0.000 abstract 1
- 229940029995 appetite stimulants Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229940097325 prolactin Drugs 0.000 abstract 1
- 238000001525 receptor binding assay Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000191089 | 2000-06-21 | ||
JP2000275013 | 2000-09-06 | ||
JP2001116000 | 2001-04-13 | ||
PCT/JP2001/005257 WO2001098494A1 (fr) | 2000-06-21 | 2001-06-20 | Ligand de gpr8 et son adn |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60139399D1 true DE60139399D1 (de) | 2009-09-10 |
Family
ID=27343845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60139399T Expired - Lifetime DE60139399D1 (de) | 2000-06-21 | 2001-06-20 | Gpr8 ligand und dafuer kodierende dna |
Country Status (7)
Country | Link |
---|---|
US (2) | US7193033B2 (de) |
EP (1) | EP1293567B1 (de) |
AT (1) | ATE437949T1 (de) |
AU (1) | AU2001274562A1 (de) |
CA (1) | CA2413195C (de) |
DE (1) | DE60139399D1 (de) |
WO (1) | WO2001098494A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE371863T1 (de) | 2001-05-15 | 2007-09-15 | Takeda Pharmaceutical | Screening-verfahren |
ATE400584T1 (de) * | 2001-06-14 | 2008-07-15 | Takeda Pharmaceutical | Neuer ligand und dna davon |
WO2003057236A1 (fr) * | 2001-12-28 | 2003-07-17 | Takeda Chemical Industries, Ltd. | Inhibiteur de prise de poids corporel |
WO2003081234A2 (en) * | 2002-03-26 | 2003-10-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with homo sapiens g - protein - coupled receptor 8 (gpr8) |
WO2003082907A1 (en) * | 2002-03-29 | 2003-10-09 | Euroscreen Sa | Ligands for g protein coupled receptor gpr7 and uses thereof |
AU2003277553A1 (en) * | 2002-11-06 | 2004-06-07 | Takeda Pharmaceutical Company Limited | Antidiuretics |
JP2004292444A (ja) * | 2003-03-13 | 2004-10-21 | Takeda Chem Ind Ltd | 上部消化管疾患の予防・治療剤 |
JP4504098B2 (ja) * | 2003-05-28 | 2010-07-14 | 武田薬品工業株式会社 | 抗体およびその用途 |
WO2004106382A1 (ja) * | 2003-05-28 | 2004-12-09 | Takeda Pharmaceutical Company Limited | 抗体およびその用途 |
CN101631454A (zh) | 2006-12-08 | 2010-01-20 | 衣阿华州立大学研究基金公司 | 参与硝酸盐吸收和代谢的植物基因 |
KR20100061679A (ko) * | 2007-09-11 | 2010-06-08 | 몬도바이오테크 래보래토리즈 아게 | 치료적 적용을 위한 티로트로핀 방출 호르몬 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
US5591602A (en) * | 1993-11-05 | 1997-01-07 | O'dowd; Brian F. | Nucleic acid encoding opioid receptor |
JPH09121865A (ja) | 1995-10-30 | 1997-05-13 | Takeda Chem Ind Ltd | 新規g蛋白質共役型レセプター蛋白質、その製造法および用途 |
US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
EP1304376A4 (de) | 2000-07-25 | 2004-12-29 | Takeda Chemical Industries Ltd | Verfahren zur herstellung eines rekombinanten proteins |
EP1344823A4 (de) | 2000-11-30 | 2005-03-16 | Takeda Chemical Industries Ltd | Neue g-protein-gekoppelte rezeptorproteine und deren dnas |
ATE371863T1 (de) | 2001-05-15 | 2007-09-15 | Takeda Pharmaceutical | Screening-verfahren |
-
2001
- 2001-06-20 US US10/311,019 patent/US7193033B2/en not_active Expired - Fee Related
- 2001-06-20 AU AU2001274562A patent/AU2001274562A1/en not_active Abandoned
- 2001-06-20 DE DE60139399T patent/DE60139399D1/de not_active Expired - Lifetime
- 2001-06-20 CA CA2413195A patent/CA2413195C/en not_active Expired - Fee Related
- 2001-06-20 WO PCT/JP2001/005257 patent/WO2001098494A1/ja active Application Filing
- 2001-06-20 EP EP01941117A patent/EP1293567B1/de not_active Expired - Lifetime
- 2001-06-20 AT AT01941117T patent/ATE437949T1/de not_active IP Right Cessation
-
2007
- 2007-01-26 US US11/699,352 patent/US7671174B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20050153391A1 (en) | 2005-07-14 |
EP1293567B1 (de) | 2009-07-29 |
ATE437949T1 (de) | 2009-08-15 |
US7193033B2 (en) | 2007-03-20 |
EP1293567A4 (de) | 2005-02-16 |
WO2001098494A1 (fr) | 2001-12-27 |
CA2413195C (en) | 2012-01-17 |
CA2413195A1 (en) | 2002-12-17 |
EP1293567A1 (de) | 2003-03-19 |
US20080305998A1 (en) | 2008-12-11 |
AU2001274562A1 (en) | 2002-01-02 |
US7671174B2 (en) | 2010-03-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |