DE60106666D1 - Continuous process for the production of microcapsules with delayed release of water-soluble peptides - Google Patents

Continuous process for the production of microcapsules with delayed release of water-soluble peptides

Info

Publication number
DE60106666D1
DE60106666D1 DE60106666T DE60106666T DE60106666D1 DE 60106666 D1 DE60106666 D1 DE 60106666D1 DE 60106666 T DE60106666 T DE 60106666T DE 60106666 T DE60106666 T DE 60106666T DE 60106666 D1 DE60106666 D1 DE 60106666D1
Authority
DE
Germany
Prior art keywords
microcapsules
production
water
continuous process
delayed release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60106666T
Other languages
German (de)
Other versions
DE60106666T2 (en
Inventor
Nora Moyano
Jose Iturraspe
Jose Lucio Nunez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eriochem SA
Original Assignee
Eriochem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eriochem SA filed Critical Eriochem SA
Publication of DE60106666D1 publication Critical patent/DE60106666D1/en
Application granted granted Critical
Publication of DE60106666T2 publication Critical patent/DE60106666T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
DE60106666T 2000-05-03 2001-05-01 Continuous process for the preparation of sustained-release microcapsules of water-soluble peptides Expired - Lifetime DE60106666T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ARP000102102A AR023940A1 (en) 2000-05-03 2000-05-03 PROCEDURE FOR THE PRODUCTION OF PROLONGED WATERPROOF PEPTIDE MICROCAPSULES IN WATER
AR0102102 2000-05-03

Publications (2)

Publication Number Publication Date
DE60106666D1 true DE60106666D1 (en) 2004-12-02
DE60106666T2 DE60106666T2 (en) 2005-03-24

Family

ID=3460812

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60106666T Expired - Lifetime DE60106666T2 (en) 2000-05-03 2001-05-01 Continuous process for the preparation of sustained-release microcapsules of water-soluble peptides

Country Status (6)

Country Link
US (1) US6534094B2 (en)
EP (1) EP1151748B1 (en)
AR (1) AR023940A1 (en)
AT (1) ATE280573T1 (en)
DE (1) DE60106666T2 (en)
ES (1) ES2230231T3 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000156A1 (en) * 2001-06-22 2003-01-03 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
CN1194688C (en) * 2001-07-03 2005-03-30 山东绿叶制药股份有限公司 Slow releasing microspheres of transcutaneous huperzine A and its derivative or salt for injection and its preparing process
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
KR101175774B1 (en) * 2002-11-04 2012-08-21 오션 뉴트리션 캐나다 리미티드 Microcapsules having multiple shells and method for the preparation thereof
RU2358795C2 (en) * 2003-10-16 2009-06-20 Базелль Полиолефин Италия С.Р.Л. Continuous emulsification method
US8808746B2 (en) * 2004-04-30 2014-08-19 Fresenius Kabi Usa, Llc Sustained-release microspheres and methods of making and using same
US6969530B1 (en) 2005-01-21 2005-11-29 Ocean Nutrition Canada Ltd. Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
US20080139649A1 (en) * 2005-01-27 2008-06-12 Barrow Colin J Fatty Acid-Benzenediol Derivatives and Methods of Making and Using Thereof
AR048220A1 (en) * 2005-01-28 2006-04-12 Lkm S A Lab ARRANGEMENT OF DEVICES USED IN THE ELABORATION OF MICROCAPSULES FOR THE CONTROLLED RELEASE OF PEPTIDES AND PROCEDURE OF ELABORATION OF SAID OPTIONALLY REPLACED
WO2006123361A2 (en) * 2005-03-01 2006-11-23 Sun Pharmaceutical Industries Limited Microspheres containing goserelin or a pharmaceutically acceptable salt thereof
WO2006123359A2 (en) * 2005-03-01 2006-11-23 Sun Pharmaceutical Industries Limited A process of making microspheres
KR100622996B1 (en) 2005-03-03 2006-09-14 한국과학기술원 Nonporous microspheres including drug and manufacturing method thereof
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
US8882747B2 (en) * 2005-11-09 2014-11-11 The Invention Science Fund I, Llc Substance delivery system
JP2009533490A (en) * 2006-04-07 2009-09-17 オーシャン ニュートリッション カナダ リミテッド Emulsions and microcapsules containing substances with low interfacial tension, and methods of making and using them
NZ596403A (en) * 2006-06-05 2013-02-22 Ocean Nutrition Canada Ltd Microcapsules with improved shells with wax in the outer shell
KR100853309B1 (en) 2006-11-01 2008-08-20 나재운 Bio-degradable nanoparticles of polyDL-lactide-co-glycolide encapsulating ciprofloxacin HCl having extended-release properties, and manufacturing method thereof
KR100816065B1 (en) * 2006-11-27 2008-03-24 동국제약 주식회사 Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby
CN101641087B (en) 2007-01-10 2013-08-21 加拿大海洋营养食品有限公司 Vegetarian microcapsules
EP2979729A3 (en) 2007-02-05 2016-05-11 Apellis Pharmaceuticals, Inc. Compstatin analogues for use in the treatment of inflammatory conditions of the respiratory system
US8673859B2 (en) * 2007-03-20 2014-03-18 New York University GM-CSF cosmeceutical compositions and methods of use thereof
EP2090605B1 (en) * 2008-02-13 2011-07-13 Bayer MaterialScience AG Method for making polycarbonates
WO2010121307A1 (en) * 2009-04-21 2010-10-28 The University Of Queensland Complex emulsions
US20110053776A1 (en) * 2009-09-01 2011-03-03 Bahr James T Blends of micro-encapsulated pesticide formulations
MX2012006441A (en) * 2009-12-22 2012-06-28 Takeda Pharmaceutical Sustained-release formulation.
ES2513569T3 (en) * 2010-06-25 2014-10-27 Takeda Pharmaceutical Company Limited Prolonged release formulation comprising a metastin derivative
CN103857465B (en) * 2011-09-13 2017-07-28 理研维他命股份有限公司 The manufacture method of multi-core type gelatin microcapsule
ES2746057T3 (en) 2011-12-14 2020-03-04 Abraxis Bioscience Llc Use of polymeric excipients for lyophilization or freezing of particles
CN103191021A (en) * 2012-01-10 2013-07-10 山东绿叶制药有限公司 Equipment for continuously producing microspheres and application of equipment
EP2689835B1 (en) * 2012-07-26 2019-05-08 Papierfabrik August Koehler SE Aromatic oil encapsulation
EP2934562A1 (en) * 2012-08-14 2015-10-28 Wockhardt Limited Pharmaceutical microparticulate compositions of polypeptides
JP6135292B2 (en) * 2013-05-10 2017-05-31 ニプロ株式会社 Method for producing microcapsule preparation
KR101686986B1 (en) * 2014-07-28 2016-12-16 에스케이케미칼주식회사 Immediate-release and sustained-release pharmaceutical compositon comprising leuprolide
US20190380967A1 (en) * 2017-01-23 2019-12-19 Savior Lifetec Corporation Preparation of microparticles of an active ingredient
CN107766606B (en) * 2017-09-01 2020-03-31 燕山大学 Method for improving lubricating property of emulsion process of direct injection system of secondary cold rolling unit
KR102171829B1 (en) 2019-11-15 2020-10-29 한국신발피혁연구원 Chloroprene foam composition for wet suit
CN111000798B (en) * 2019-12-26 2021-11-23 四川恒博生物科技有限公司 Non-operative castration injection for dogs by adopting in-situ gel technology
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
CN115501143B (en) * 2022-10-21 2023-08-22 中科未来(无锡)生物技术研究院有限公司 Anti-allergy relieving composition containing saussurea involucrata culture and preparation method thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800457A (en) 1953-06-30 1957-07-23 Ncr Co Oil-containing microscopic capsules and method of making them
FR1362934A (en) 1962-07-11 1964-06-05 Gevaert Photo Prod Nv Method for the encapsulation of water and compounds in the aqueous phase
FR1362933A (en) 1962-07-11 1964-06-05 Gevaert Photo Prod Nv Process for the encapsulation of water and compounds in the aqueous phase
US3297033A (en) 1963-10-31 1967-01-10 American Cyanamid Co Surgical sutures
BE744162A (en) 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd ENCAPSULATION PROCESS
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3839297A (en) 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
GB1413186A (en) 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
DE2438350C3 (en) 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptides with a strong LH-RH / FSH-RH action, process for their production and pharmaceutical preparations containing them
US4010125A (en) 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
GB1524747A (en) 1976-05-11 1978-09-13 Ici Ltd Polypeptide
US4234571A (en) 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4273920A (en) 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4675189A (en) 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
CH653553A5 (en) * 1982-11-01 1986-01-15 Sandoz Ag Microencapsulation process
CH661206A5 (en) 1983-09-23 1987-07-15 Debiopharm Sa PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF HORMONDEPENDENT DISEASES.
JPS60100516A (en) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd Preparation of sustained release microcapsule
DE3678308D1 (en) 1985-02-07 1991-05-02 Takeda Chemical Industries Ltd METHOD FOR PRODUCING MICROCAPSULES.
US5271945A (en) 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
DE69220317T2 (en) 1991-10-01 1997-10-16 Takeda Chemical Industries Ltd Microparticle summary for extended release and manufacture of the same
FR2693905B1 (en) 1992-07-27 1994-09-02 Rhone Merieux Process for the preparation of microspheres for the sustained release of the hormone LHRH and its analogs, microspheres and formulations obtained.
DE69316101T2 (en) 1992-08-07 1998-10-22 Takeda Chemical Industries Ltd Manufacture of microcapsules containing water-soluble drugs
JPH09505308A (en) * 1993-11-19 1997-05-27 アルカーミズ・コントロールド・セラピューティクス・インコーポレイテッド・トゥー Production of biodegradable microparticles containing biologically active agents
FR2718642B1 (en) * 1994-04-15 1996-07-12 Pf Medicament Biodegradable controlled release microspheres and their preparation process.
JP2909418B2 (en) 1995-09-18 1999-06-23 株式会社資生堂 Delayed release microsphere of drug
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
DE19925184A1 (en) * 1999-05-26 2000-11-30 Schering Ag Continuous process for the production of morphologically uniform micro and nanoparticles by means of a micromixer as well as particles produced by this process

Also Published As

Publication number Publication date
EP1151748A1 (en) 2001-11-07
AR023940A1 (en) 2002-09-04
US6534094B2 (en) 2003-03-18
US20020031553A1 (en) 2002-03-14
ATE280573T1 (en) 2004-11-15
EP1151748B1 (en) 2004-10-27
ES2230231T3 (en) 2005-05-01
DE60106666T2 (en) 2005-03-24

Similar Documents

Publication Publication Date Title
DE60106666D1 (en) Continuous process for the production of microcapsules with delayed release of water-soluble peptides
HUP0203875A3 (en) Microcapsule and process for production thereof
DE60043983D1 (en) PROCESS FOR THE PRODUCTION OF PHENYLALKANES
HK1063589A1 (en) Personal ornament having white coating film and process for producing the same.
DE60121878D1 (en) Microactuator and its production process
PL371671A1 (en) Method for producing cyclohexane dicarboxylic acids and the derivatives thereof
DE60122533D1 (en) PISTON AND METHOD FOR THE PRODUCTION
DE69922288D1 (en) Micropump and manufacturing process for the micropump
HK1049355A1 (en) Personal ornament having white coating layer and process for producing the same
DE60017550D1 (en) CASTING FOR THE PRODUCTION OF CONTACT LENSES
ID26478A (en) DESCRIPTION OF THE FIRST KINDS OF PRODUCTION STEPS
DE69837984D1 (en) Colored photoresists and methods and articles comprising them
DE60219188D1 (en) PROCESS FOR THE PRODUCTION OF OLEFINES.
AU2002327085A1 (en) Sustained release micropellets and process for producing the same
AR028078A1 (en) PROCESS FOR THE PRODUCTION OF ENZYME GRRNULES
ZA200204816B (en) Processes and organisms for the production of anti-freeze proteins.
DE60225585D1 (en) SUSPENSION PROCESS FOR HYDRO-ISOLATED HYDROGENOMERY IN THE SYNTHETIC ACTIVE HYDROGENOMERY.
IT1305122B1 (en) TRIMETHYLALKANE PRODUCTION PROCESS.
DE60107042D1 (en) Process for the production of microencapsulated gyricon balls
BR0015986B1 (en) process for the continuous production of copolyamides.
DE10085304T1 (en) Mechanical fastening system with several engagement parts that contain stem parts
IS5019A (en) Process for the production of hydroxamic acids
DE60134845D1 (en) NEW PROCESS FOR THE PREPARATION OF POLYACETYLENE DERIVATIVES
DE60113323D1 (en) Process for the preparation of L-phenylalanine
EP1273657A4 (en) Novel protein, process for producing the same and use thereof

Legal Events

Date Code Title Description
8364 No opposition during term of opposition