DE60044717D1 - Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen - Google Patents
Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungenInfo
- Publication number
- DE60044717D1 DE60044717D1 DE60044717T DE60044717T DE60044717D1 DE 60044717 D1 DE60044717 D1 DE 60044717D1 DE 60044717 T DE60044717 T DE 60044717T DE 60044717 T DE60044717 T DE 60044717T DE 60044717 D1 DE60044717 D1 DE 60044717D1
- Authority
- DE
- Germany
- Prior art keywords
- recipient
- prevention
- treatment
- rejection
- xenografts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9910835.9A GB9910835D0 (en) | 1999-05-10 | 1999-05-10 | Organic compounds |
GBGB9925443.5A GB9925443D0 (en) | 1999-10-27 | 1999-10-27 | Organic compounds |
PCT/EP2000/004250 WO2000067773A2 (en) | 1999-05-10 | 2000-05-10 | Combinations of immunosupressive agents for the treatment or prevention of graft rejections |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60044717D1 true DE60044717D1 (de) | 2010-09-02 |
Family
ID=26315533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60044717T Expired - Lifetime DE60044717D1 (de) | 1999-05-10 | 2000-05-10 | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
Country Status (7)
Country | Link |
---|---|
US (5) | US20020132764A1 (de) |
EP (2) | EP1181034B1 (de) |
JP (1) | JP2002544167A (de) |
AT (1) | ATE474590T1 (de) |
AU (1) | AU4565000A (de) |
DE (1) | DE60044717D1 (de) |
WO (1) | WO2000067773A2 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1208847E (pt) * | 1996-07-30 | 2007-07-24 | Novartis Ag | Composições farmacêuticas para o tratamento da rejeição de transplantes, doenças autoimunes ou inflamatórias compreendendo ciclosporina a e 40-0-(2-hidroxietil)-rapamicina |
AU3095601A (en) | 2000-01-14 | 2001-07-24 | Univ Pennsylvania | O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders |
GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
CA2924681C (en) | 2013-09-24 | 2019-12-31 | Giner, Inc. | System for gas treatment of a cell implant |
US11033666B2 (en) | 2016-11-15 | 2021-06-15 | Giner Life Sciences, Inc. | Percutaneous gas diffusion device suitable for use with a subcutaneous implant |
US11642501B2 (en) | 2017-05-04 | 2023-05-09 | Giner, Inc. | Robust, implantable gas delivery device and methods, systems and devices including same |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5178858A (en) * | 1987-12-02 | 1993-01-12 | Reichert Thomas A | Method for prevention of graft versus host disease |
US5135934A (en) | 1990-07-06 | 1992-08-04 | Du Pont Merck Pharmaceutical Company | 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents |
ATE232730T1 (de) | 1991-08-23 | 2003-03-15 | Alberta Res Council | Verfahren und zusammensetzungen zur verhinderung der antikörper-vermittelten abstossung von xenogenen transplantaten |
US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
GB9221220D0 (en) | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
US5843452A (en) * | 1992-11-09 | 1998-12-01 | Pharmagenesis, Inc. | Immunotherapy composition and method |
EP0804734B1 (de) | 1994-05-13 | 2005-05-04 | Miltenyi Biotec GmbH | An protein gebundene sterile und pyrogenfreie säulen zum binden und entfernen von substanzen aus blut |
US5624946A (en) * | 1994-07-05 | 1997-04-29 | Williams; James | Use of leflunomide to control and reverse chronic allograft rejection |
IL115742A (en) | 1994-10-26 | 2000-06-01 | Novartis Ag | Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant |
US5697109A (en) | 1994-10-28 | 1997-12-16 | Barton Medical Corporation | Patient transport system |
US5631282A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | Triterpenes |
BE1009856A5 (fr) | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
GB9601120D0 (en) | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
ID18663A (id) | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
PT1208847E (pt) * | 1996-07-30 | 2007-07-24 | Novartis Ag | Composições farmacêuticas para o tratamento da rejeição de transplantes, doenças autoimunes ou inflamatórias compreendendo ciclosporina a e 40-0-(2-hidroxietil)-rapamicina |
GB9619706D0 (en) | 1996-09-20 | 1996-11-06 | Pharmacia Spa | Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und |
US5962415A (en) * | 1996-09-20 | 1999-10-05 | Bristol-Myers Squibb Co. | Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof |
WO1998047915A1 (en) | 1997-04-18 | 1998-10-29 | Novartis Ag | Neoglycoproteins |
WO1999003336A1 (fr) | 1997-07-14 | 1999-01-28 | Nippon Meat Packers, Inc. | Mammiferes transgeniques |
-
2000
- 2000-05-10 AT AT00927193T patent/ATE474590T1/de active
- 2000-05-10 DE DE60044717T patent/DE60044717D1/de not_active Expired - Lifetime
- 2000-05-10 WO PCT/EP2000/004250 patent/WO2000067773A2/en active Application Filing
- 2000-05-10 AU AU45650/00A patent/AU4565000A/en not_active Abandoned
- 2000-05-10 EP EP00927193A patent/EP1181034B1/de not_active Expired - Lifetime
- 2000-05-10 JP JP2000616798A patent/JP2002544167A/ja active Pending
- 2000-05-10 EP EP08158054A patent/EP1980263A1/de not_active Withdrawn
-
2001
- 2001-11-07 US US10/035,663 patent/US20020132764A1/en not_active Abandoned
-
2005
- 2005-07-11 US US11/178,573 patent/US20050277585A1/en not_active Abandoned
-
2006
- 2006-11-15 US US11/599,814 patent/US20070060511A1/en not_active Abandoned
-
2008
- 2008-04-24 US US12/109,210 patent/US20080199478A1/en not_active Abandoned
-
2011
- 2011-02-11 US US13/025,347 patent/US8435520B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE474590T1 (de) | 2010-08-15 |
AU4565000A (en) | 2000-11-21 |
US20080199478A1 (en) | 2008-08-21 |
US20020132764A1 (en) | 2002-09-19 |
US20050277585A1 (en) | 2005-12-15 |
US8435520B2 (en) | 2013-05-07 |
EP1980263A1 (de) | 2008-10-15 |
US20110142953A1 (en) | 2011-06-16 |
EP1181034A2 (de) | 2002-02-27 |
WO2000067773A2 (en) | 2000-11-16 |
JP2002544167A (ja) | 2002-12-24 |
EP1181034B1 (de) | 2010-07-21 |
US20070060511A1 (en) | 2007-03-15 |
WO2000067773A3 (en) | 2001-06-28 |
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