DE60042836D1 - POLYNUCLEOTIDE CODING FOR THE RG1 POLYPEPTIDE - Google Patents

POLYNUCLEOTIDE CODING FOR THE RG1 POLYPEPTIDE

Info

Publication number
DE60042836D1
DE60042836D1 DE60042836T DE60042836T DE60042836D1 DE 60042836 D1 DE60042836 D1 DE 60042836D1 DE 60042836 T DE60042836 T DE 60042836T DE 60042836 T DE60042836 T DE 60042836T DE 60042836 D1 DE60042836 D1 DE 60042836D1
Authority
DE
Germany
Prior art keywords
polypeptides
polypeptide
polynucleotide coding
methods
polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60042836T
Other languages
German (de)
Inventor
Richard Harkins
Deborah Parkes
Gordon Parry
Douglas W Schneider
Renate Steinbrecher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Application granted granted Critical
Publication of DE60042836D1 publication Critical patent/DE60042836D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to novel human extracellular matrix polypeptides, designated RG1, polynucleotides encoding the polypeptides, methods for producing the polypeptides, expression vectors and genetically engineered host cells for expression of the polypeptides. The invention further relates to methods for utilizing the polynucleotides and polypeptides in research, diagnosis, and therapeutic applications.
DE60042836T 1999-12-16 2000-12-15 POLYNUCLEOTIDE CODING FOR THE RG1 POLYPEPTIDE Expired - Lifetime DE60042836D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17237099P 1999-12-16 1999-12-16
US09/732,357 US6682902B2 (en) 1999-12-16 2000-12-07 DNA encoding a novel RG1 polypeptide
PCT/US2000/033901 WO2001044291A2 (en) 1999-12-16 2000-12-15 Polynucleotid encoding the rg1 polypeptide

Publications (1)

Publication Number Publication Date
DE60042836D1 true DE60042836D1 (en) 2009-10-08

Family

ID=26868022

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60042836T Expired - Lifetime DE60042836D1 (en) 1999-12-16 2000-12-15 POLYNUCLEOTIDE CODING FOR THE RG1 POLYPEPTIDE

Country Status (32)

Country Link
US (5) US6682902B2 (en)
EP (2) EP1237915B1 (en)
JP (1) JP4979867B2 (en)
KR (1) KR100752434B1 (en)
CN (1) CN1297566C (en)
AT (1) ATE440862T1 (en)
AU (1) AU784674B2 (en)
BG (1) BG65898B1 (en)
BR (1) BR0017022A (en)
CA (1) CA2394574A1 (en)
CZ (1) CZ299232B6 (en)
DE (1) DE60042836D1 (en)
DK (1) DK1237915T3 (en)
EE (1) EE05293B1 (en)
ES (1) ES2331106T3 (en)
HR (1) HRP20020549B1 (en)
HU (1) HU229001B1 (en)
IL (2) IL150115A0 (en)
LT (1) LT5046B (en)
ME (1) MEP37808A (en)
MX (1) MXPA02005914A (en)
NO (1) NO330924B1 (en)
NZ (1) NZ519598A (en)
PL (1) PL207634B1 (en)
PT (1) PT1237915E (en)
RO (1) RO122543B1 (en)
RS (1) RS50831B (en)
RU (1) RU2283130C2 (en)
SI (2) SI1237915T1 (en)
SK (2) SK286384B6 (en)
WO (1) WO2001044291A2 (en)
ZA (1) ZA200205638B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020161199A1 (en) * 1998-04-08 2002-10-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP1251139A3 (en) * 1998-04-08 2002-12-18 Genentech, Inc. Human mindin-like protein and nucleic acids encoding it
US6960433B1 (en) 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20070031901A1 (en) * 1999-03-08 2007-02-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
UY28424A1 (en) * 2003-07-22 2005-02-28 Schering Ag RGI ANTIBODIES AND USES OF THE SAME.
US7294704B2 (en) 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
TWI438207B (en) * 2007-02-21 2014-05-21 Oncotherapy Science Inc Peptide vaccines for cancers expressing tumor-associated antigens
TW200930407A (en) * 2007-11-30 2009-07-16 Medarex Inc Conjugates of anti-RG-1 antibodies
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN102346184B (en) * 2010-08-03 2014-03-26 中国人民解放军军事医学科学院生物工程研究所 Novel application of Spondin-2 (SPON2)
DE202012012998U1 (en) 2011-08-31 2014-06-13 Daniel Elias Bioactive, regenerative mixture for the preparation of a supplementary food

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657760A (en) 1979-03-20 1987-04-14 Ortho Pharmaceutical Corporation Methods and compositions using monoclonal antibody to human T cells
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US5246692A (en) * 1986-09-05 1993-09-21 The United States Of America As Represented By The Secretary Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5399493A (en) 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
US5437994A (en) 1989-06-15 1995-08-01 Regents Of The University Of Michigan Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
US5225212A (en) 1989-10-20 1993-07-06 Liposome Technology, Inc. Microreservoir liposome composition and method
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
WO1992003918A1 (en) 1990-08-29 1992-03-19 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1993023057A1 (en) 1992-05-14 1993-11-25 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting cancer development
US5871969A (en) 1996-02-12 1999-02-16 Human Genome Sciences, Inc. Nucleic acids encoding human neuronal attachment factor-1
US6287777B1 (en) 1996-05-10 2001-09-11 Beth Israel Deaconess Medical Center NPG-1 gene that is differentially expressed in prostate tumors
US6177244B1 (en) 1996-05-10 2001-01-23 Beth Israel Deaconess Medical Center Inc. NPG-1 gene that is differentially expressed in prostate tumors
US5804382A (en) 1996-05-10 1998-09-08 Beth Israel Deaconess Medical Center, Inc. Methods for identifying differentially expressed genes and differences between genomic nucleic acid sequences
JP3494529B2 (en) * 1996-06-06 2004-02-09 Ｙｋｋ株式会社 Integral molded surface fastener
CA2263895C (en) * 1996-08-26 2012-06-26 University Of Washington Therapeutic and diagnostic applications of perlecan domain i splice variants
AU6961398A (en) 1997-04-10 1998-10-30 Zymogenetics Inc. Secreted f-spondin homologs
EP1002090A2 (en) * 1997-05-06 2000-05-24 Human Genome Sciences, Inc. $i(ENTEROCOCCUS FAECALIS) POLYNUCLEOTIDES AND POLYPEPTIDES
WO1998050073A1 (en) 1997-05-09 1998-11-12 Smithkline Beecham Corporation Integrin ligand, human mindin
ES2312205T3 (en) 1998-03-10 2009-02-16 Genentech, Inc. NEW POLYPEPTIDE AND NUCLEIC ACIDS THAT CODE IT.
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US6960433B1 (en) * 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
WO2000023108A1 (en) 1998-10-19 2000-04-27 Diadexus Llc Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
EE05627B1 (en) * 1998-12-23 2013-02-15 Pfizer Inc. Human monoclonal antibodies to CTLA-4
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
US6682902B2 (en) 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide

Also Published As

Publication number Publication date
PT1237915E (en) 2009-11-04
RS50831B (en) 2010-08-31
US7307154B2 (en) 2007-12-11
US20090214422A1 (en) 2009-08-27
RU2002119208A (en) 2004-02-27
BR0017022A (en) 2002-11-05
WO2001044291A2 (en) 2001-06-21
ATE440862T1 (en) 2009-09-15
US20040152139A1 (en) 2004-08-05
AU784674B2 (en) 2006-05-25
KR100752434B1 (en) 2007-08-27
NZ519598A (en) 2004-03-26
CZ299232B6 (en) 2008-05-21
CN1434832A (en) 2003-08-06
MXPA02005914A (en) 2003-02-27
HRP20020549A2 (en) 2004-04-30
CN1297566C (en) 2007-01-31
EP2048157B1 (en) 2012-10-10
HU229001B1 (en) 2013-07-29
IL150115A0 (en) 2002-12-01
EP2048157A1 (en) 2009-04-15
SI21140A (en) 2003-08-31
BG65898B1 (en) 2010-04-30
NO20022836L (en) 2002-08-15
AU3074601A (en) 2001-06-25
ES2331106T3 (en) 2009-12-22
US20090292112A1 (en) 2009-11-26
CA2394574A1 (en) 2001-06-21
HUP0204224A2 (en) 2003-03-28
NO20022836D0 (en) 2002-06-14
LT2002070A (en) 2003-04-25
MEP37808A (en) 2011-05-10
US6682902B2 (en) 2004-01-27
PL356220A1 (en) 2004-06-28
SK286384B6 (en) 2008-08-05
WO2001044291A3 (en) 2002-01-17
PL207634B1 (en) 2011-01-31
DK1237915T3 (en) 2009-11-16
US20040023307A1 (en) 2004-02-05
IL150115A (en) 2013-11-28
EP1237915A2 (en) 2002-09-11
SK8482002A3 (en) 2003-02-04
RU2283130C2 (en) 2006-09-10
EP1237915B1 (en) 2009-08-26
SK288147B6 (en) 2013-12-02
US7893217B2 (en) 2011-02-22
BG106823A (en) 2003-04-30
ZA200205638B (en) 2003-10-15
NO330924B1 (en) 2011-08-22
SI1237915T1 (en) 2009-12-31
EE05293B1 (en) 2010-04-15
JP4979867B2 (en) 2012-07-18
US20020004047A1 (en) 2002-01-10
HUP0204224A3 (en) 2004-12-28
HRP20020549B1 (en) 2013-09-30
LT5046B (en) 2003-08-25
YU44602A (en) 2005-06-10
JP2003521244A (en) 2003-07-15
EE200200323A (en) 2003-10-15
US7887804B2 (en) 2011-02-15
KR20020065575A (en) 2002-08-13
RO122543B1 (en) 2009-08-28

Similar Documents

Publication Publication Date Title
ATE440862T1 (en) POLYNUCLEOTIDE CODING FOR THE RG1 POLYPEPTIDE
DE60330923D1 (en) Human coagulation factor VII polypeptides
ATE440951T1 (en) EXTENDED CDNS CODING SECRETED PROTEINS
ATE352626T1 (en) POLYPEPTIDES WITH GALACTOSE OXIDASE ACTIVITY AND NUCLEIC ACIDS CODING THEREFOR
WO2003080856A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
BR9910396A (en) Polynucleotide (s) and basb029 polypeptides from neisseria meningitidis
ATE285416T1 (en) EXPRESSION AND PURIFICATION OF CLONED HUMAN ALPHA FETOPROTEIN
DE60118359D1 (en) HUMAN PELLINO POLYPEPTIDE
ATE155526T1 (en) POLYPEPTIDE HAVING HUMAN MONOCYTE CHEMOTACTIC FACTOR ACTIVITY AND DNA CODING THE POLYPEPTIDE
NZ516237A (en) Meth1 and meth2 polynucleotides and polypeptides
WO2003029423A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
ES2150937T3 (en) AUTOTAXIN: STIMULATING PROTEIN OF USEFUL MOTILITY IN DIAGNOSIS AND CANCER THERAPY.
WO2001081577A3 (en) Dna encoding the prost 03 polypeptide
ES8605296A1 (en) Recominant factor VIII-R.
DE59109085D1 (en) Epididymis-specific polypeptides and their use
WO2003085124A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
ATE554793T1 (en) CONJUGATE
ATE394420T1 (en) GENE RELATED TO HAIR LOSS, THE POLYPEPTIDE ENCODED BY IT AND USES THEREOF
DE60120507D1 (en) HUMAN LEUCINE AREAS REPEATS CONTAINING PROTEIN, PRESENTLY EXPRESSED IN THE THIN DARN, HLRRSI1
WO2003050245A8 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2003004617A8 (en) Novel human proteins, polynucleotides encoding them and methods of using the same
WO2004055158A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2003064629A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
ATE311458T1 (en) BASB111 POLYPEPTIDE AND POLYNUCLEOTIDE FROM MORAXELLA CATHARRALIS

Legal Events

Date Code Title Description
8364 No opposition during term of opposition