DE60040156D1 - Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten - Google Patents
Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamentenInfo
- Publication number
- DE60040156D1 DE60040156D1 DE60040156T DE60040156T DE60040156D1 DE 60040156 D1 DE60040156 D1 DE 60040156D1 DE 60040156 T DE60040156 T DE 60040156T DE 60040156 T DE60040156 T DE 60040156T DE 60040156 D1 DE60040156 D1 DE 60040156D1
- Authority
- DE
- Germany
- Prior art keywords
- electroporation
- gene
- protein
- array
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12981799P | 1999-04-16 | 1999-04-16 | |
PCT/US2000/010337 WO2000062855A1 (en) | 1999-04-16 | 2000-04-17 | Apparatus for electroporation of gene, protein, or drug therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60040156D1 true DE60040156D1 (de) | 2008-10-16 |
Family
ID=22441736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040156T Expired - Fee Related DE60040156D1 (de) | 1999-04-16 | 2000-04-17 | Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten |
Country Status (6)
Country | Link |
---|---|
US (1) | US6593130B1 (de) |
EP (1) | EP1210144B1 (de) |
AT (1) | ATE406936T1 (de) |
AU (1) | AU4465600A (de) |
DE (1) | DE60040156D1 (de) |
WO (1) | WO2000062855A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8177743B2 (en) | 1998-05-18 | 2012-05-15 | Boston Scientific Scimed, Inc. | Localized delivery of drug agents |
US7729756B2 (en) * | 2000-01-18 | 2010-06-01 | Siemens Aktiengesellschaft | Measurement system for examining a section of tissue on a patient and the use of a measurement system of this type |
US8263756B2 (en) * | 2001-04-06 | 2012-09-11 | Chugai Seiyaku Kabushiki Kaisha | Method of gene transfer via vascular system or ureter |
WO2003047689A1 (en) * | 2001-11-29 | 2003-06-12 | Microlin Llc | Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices |
US7104985B2 (en) * | 2003-03-06 | 2006-09-12 | Martinelli Michael A | Apparatus and method for causing selective necrosis of abnormal cells |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US8802643B1 (en) | 2003-05-30 | 2014-08-12 | University Of South Florida | Method for the treatment of malignancies |
WO2004110371A2 (en) | 2003-05-30 | 2004-12-23 | University Of South Florida | Method for the treatment of malignancies |
WO2006085987A2 (en) * | 2004-07-09 | 2006-08-17 | University Of Iowa Research Foundation | Rna interference in respiratory epitheial cells |
US7729761B2 (en) * | 2004-07-14 | 2010-06-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlled gene or protein delivery |
US7776373B2 (en) * | 2004-11-19 | 2010-08-17 | Eteka Llc | Apparatus and method for the enhancement of food properties and food prepared therefrom |
US8101169B2 (en) * | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
US7923251B2 (en) * | 2005-02-23 | 2011-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for avalanche-mediated transfer of agents into cells |
EP1865969A4 (de) * | 2005-03-19 | 2009-07-15 | Univ California | Ultraschwach elektrofeldnetz-vermittelte ex vivo gen-, protein- und arzneiabgabe in zellen |
EP1759714A1 (de) * | 2005-09-02 | 2007-03-07 | Bioalliance Pharma | Elektrotransfer von Nukleinsäuren in Gewebezellen |
WO2007117651A2 (en) * | 2006-04-07 | 2007-10-18 | University Of South Florida | Passive electric field focus system for in vivo and in vitro applications |
US20100121253A1 (en) * | 2007-03-14 | 2010-05-13 | The Regents Of The University Of California | Method and Apparatus of Low Strength Electric Field Network-Mediated Delivery of Drug, Gene, SI-RNA, SH-RNA Protein, Peptide, Antibody or Other Biomedical and Therapeutic Molecules and Reagents in Solid Organs |
US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
US20090227948A1 (en) * | 2008-03-06 | 2009-09-10 | Boston Scientific Scimed, Inc. | Balloon catheter devices with sheath covering |
CN101274120B (zh) | 2008-04-29 | 2013-03-13 | 圣太科医疗科技(上海)有限公司 | 生物与医用多路低电压微电场发生仪 |
EP2662027B1 (de) | 2008-05-09 | 2017-09-27 | Holaira, Inc. | Systeme, Baugruppen und Verfahren zur Behandlung eines Bronchialbaumes |
WO2009140161A1 (en) * | 2008-05-13 | 2009-11-19 | Bio-Rad Laboratories, Inc. | Electroporation of adherent cells with an array of closely spaced electrodes |
EP2319913A4 (de) * | 2008-07-18 | 2013-08-28 | Suntek Medical Scient And Technologies Shanghai | Mehrzweck-mikroelektrisches-feld-netzwerk-zellprozessierungsvorrichtung |
US20110125081A1 (en) * | 2008-07-18 | 2011-05-26 | Luyi Sen | Drug delivery apparatus guided by Micro Electrical Field Network for target cell of liver |
US8207138B2 (en) | 2009-05-19 | 2012-06-26 | Medtronic, Inc. | Methods and devices for improved efficiency of RNA delivery to cells |
US20100298697A1 (en) * | 2009-05-19 | 2010-11-25 | Medtronic, Inc. | Method and devices for improved efficiency of rna delivery to cells |
US8932055B2 (en) * | 2009-06-11 | 2015-01-13 | Roberto Armanino | Method employing electric fields to selectively kill microbes in a root canal preparation |
EP2445584A4 (de) | 2009-06-24 | 2014-06-11 | Internat Scient Pty Ltd | Vorrichtung und behandlungsverfahren mit einem variierenden elektromagnetischen energisierungsprofil |
EP2470232B1 (de) * | 2009-08-27 | 2016-03-30 | Boston Scientific Scimed, Inc. | Ballonkathetervorrichtungen mit wirkstoffbeschichteter schleuse |
CA2779135C (en) | 2009-10-27 | 2018-09-04 | Innovative Pulmonary Solutions, Inc. | Delivery devices with coolable energy emitting assemblies |
US8870857B2 (en) | 2009-11-05 | 2014-10-28 | Greatbatch Ltd. | Waveguide neural interface device |
US9149328B2 (en) | 2009-11-11 | 2015-10-06 | Holaira, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
EP2614159B1 (de) | 2010-09-10 | 2017-11-08 | Bio-Rad Laboratories, Inc. | Grössenauswahl von dna zur chromatinanalyse |
US20120208193A1 (en) | 2011-02-15 | 2012-08-16 | Bio-Rad Laboratories, Inc. | Detecting methylation in a subpopulation of genomic dna |
US8728987B2 (en) | 2011-08-03 | 2014-05-20 | Bio-Rad Laboratories, Inc. | Filtering small nucleic acids using permeabilized cells |
US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
US20210393894A1 (en) * | 2018-01-23 | 2021-12-23 | The Regents Of The University Of California | Downstream delivery of agents in solid organ transplantation |
US10918861B2 (en) * | 2018-07-24 | 2021-02-16 | Wisconsin Alumni Research Foundation | In vivo gene therapy delivery procedure and device |
CA3117715A1 (en) * | 2018-10-26 | 2020-04-30 | Kytopen Corporation | Devices, systems, and kits for electroporation and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236413B1 (en) | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5507724A (en) | 1992-07-01 | 1996-04-16 | Genetronics, Inc. | Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells |
US5304120A (en) | 1992-07-01 | 1994-04-19 | Btx Inc. | Electroporation method and apparatus for insertion of drugs and genes into endothelial cells |
US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
US5634899A (en) * | 1993-08-20 | 1997-06-03 | Cortrak Medical, Inc. | Simultaneous cardiac pacing and local drug delivery method |
US5807306A (en) | 1992-11-09 | 1998-09-15 | Cortrak Medical, Inc. | Polymer matrix drug delivery apparatus |
US5795755A (en) * | 1994-07-05 | 1998-08-18 | Lemelson; Jerome H. | Method of implanting living cells by laser poration at selected sites |
US6041252A (en) * | 1995-06-07 | 2000-03-21 | Ichor Medical Systems Inc. | Drug delivery system and method |
US6090617A (en) * | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
ES2273408T3 (es) | 1997-04-03 | 2007-05-01 | Electrofect As. | Metodo para introducir medicamentos y acidos nucleicos en el musculo esqueletico. |
US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
-
2000
- 2000-04-14 US US09/549,904 patent/US6593130B1/en not_active Expired - Lifetime
- 2000-04-17 DE DE60040156T patent/DE60040156D1/de not_active Expired - Fee Related
- 2000-04-17 WO PCT/US2000/010337 patent/WO2000062855A1/en active Application Filing
- 2000-04-17 EP EP00926064A patent/EP1210144B1/de not_active Expired - Lifetime
- 2000-04-17 AT AT00926064T patent/ATE406936T1/de not_active IP Right Cessation
- 2000-04-17 AU AU44656/00A patent/AU4465600A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE406936T1 (de) | 2008-09-15 |
EP1210144A1 (de) | 2002-06-05 |
US6593130B1 (en) | 2003-07-15 |
AU4465600A (en) | 2000-11-02 |
EP1210144B1 (de) | 2008-09-03 |
WO2000062855A1 (en) | 2000-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |