DE60039095D1 - Taxolverbindung und Verfahren zu ihrer Herstellung - Google Patents

Taxolverbindung und Verfahren zu ihrer Herstellung

Info

Publication number
DE60039095D1
DE60039095D1 DE60039095T DE60039095T DE60039095D1 DE 60039095 D1 DE60039095 D1 DE 60039095D1 DE 60039095 T DE60039095 T DE 60039095T DE 60039095 T DE60039095 T DE 60039095T DE 60039095 D1 DE60039095 D1 DE 60039095D1
Authority
DE
Germany
Prior art keywords
preparation
taxol compound
taxol
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039095T
Other languages
English (en)
Inventor
Tadakatsu Mandai
Hiroshi Okumoto
Katsuyoshi Nakanishi
Koji Hara
Katsuhiko Mikuni
Kozo Hara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ensuiko Sugar Refining Co Ltd
Bio Research Corp of Yokohama
Original Assignee
Ensuiko Sugar Refining Co Ltd
Bio Research Corp of Yokohama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ensuiko Sugar Refining Co Ltd, Bio Research Corp of Yokohama filed Critical Ensuiko Sugar Refining Co Ltd
Application granted granted Critical
Publication of DE60039095D1 publication Critical patent/DE60039095D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60039095T 1999-09-17 2000-03-01 Taxolverbindung und Verfahren zu ihrer Herstellung Expired - Lifetime DE60039095D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26397499A JP4502338B2 (ja) 1999-09-17 1999-09-17 タキソイド化合物の製造法

Publications (1)

Publication Number Publication Date
DE60039095D1 true DE60039095D1 (de) 2008-07-17

Family

ID=17396812

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039095T Expired - Lifetime DE60039095D1 (de) 1999-09-17 2000-03-01 Taxolverbindung und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
US (1) US6136990A (de)
EP (1) EP1085018B1 (de)
JP (1) JP4502338B2 (de)
AU (1) AU724835B1 (de)
CA (1) CA2299967C (de)
DE (1) DE60039095D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100551945B1 (ko) * 1997-12-19 2006-02-20 가부시키가이샤 야쿠루트 혼샤 택산 유도체
US6410757B1 (en) 1999-02-16 2002-06-25 Bio Research Corporation Of Yokohama Baccatin derivatives and a process for producing the same
WO2000073293A1 (en) * 1999-05-28 2000-12-07 Bristol-Myers Squibb Co. Semi-synthesis of paclitaxel using dialkyldichlorosilanes
US6479679B1 (en) * 2001-04-25 2002-11-12 Napro Biotherapeutics, Inc. Two-step conversion of protected taxane ester to paclitaxel
AU2008288651A1 (en) * 2007-08-22 2009-02-26 6570763 Canada Inc. Process for converting 9-dihydro-13-acetylbaccatin III into docetaxel or paclitaxel
JP6205530B2 (ja) * 2015-07-07 2017-09-27 忠勝 萬代 パクリタキセル及びドセタキセルの側鎖前駆体の製造方法
CN114573631B (zh) * 2022-03-10 2024-06-18 清远中大创新药物研究中心 一种利用三组分反应一步合成紫杉醇侧链及其类似物的方法及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
FR2696464B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2697522B1 (fr) * 1992-10-30 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
US6040466A (en) * 1996-03-25 2000-03-21 Rhone Poulenc Rorer Sa Taxoids, their preparation and pharmaceutical compositions containing them
US5948919A (en) * 1993-02-05 1999-09-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
ES2193154T3 (es) * 1993-03-05 2003-11-01 Univ Florida State Procedimiento para la preparacion de 9-desoxotaxanos.
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
US5786489A (en) * 1994-02-08 1998-07-28 The Scripps Research Institute Transformations of taxol
JPH09509431A (ja) * 1994-11-04 1997-09-22 フアルマシア・エツセ・ピー・アー タキサン誘導体
US5773461A (en) * 1996-06-06 1998-06-30 Bristol-Myers Squibb Company 7-deoxy-6-substituted paclitaxels
JPH11116562A (ja) * 1997-10-13 1999-04-27 Tanabe Seiyaku Co Ltd バッカチン誘導体の製法
US5917062A (en) * 1997-11-21 1999-06-29 Indena S.P.A Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
US6066748A (en) * 1997-12-17 2000-05-23 Han; Man Woo Process of extracting TAXOL® from taxus cuspidata
US6066749A (en) * 1998-05-01 2000-05-23 Napro Biotherapeutics, Inc. Method for conversion of C-2'-O-protected-10-hydroxy taxol to c-2'-O-protected taxol:useful intermediates in paclitaxel synthesis
US6410757B1 (en) * 1999-02-16 2002-06-25 Bio Research Corporation Of Yokohama Baccatin derivatives and a process for producing the same

Also Published As

Publication number Publication date
JP4502338B2 (ja) 2010-07-14
CA2299967C (en) 2005-04-19
AU724835B1 (en) 2000-09-28
CA2299967A1 (en) 2001-03-17
EP1085018A1 (de) 2001-03-21
JP2001089464A (ja) 2001-04-03
US6136990A (en) 2000-10-24
EP1085018B1 (de) 2008-06-04

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