DE60030450D1 - Von MUC-1 abgeleitete Peptide - Google Patents
Von MUC-1 abgeleitete PeptideInfo
- Publication number
- DE60030450D1 DE60030450D1 DE60030450T DE60030450T DE60030450D1 DE 60030450 D1 DE60030450 D1 DE 60030450D1 DE 60030450 T DE60030450 T DE 60030450T DE 60030450 T DE60030450 T DE 60030450T DE 60030450 D1 DE60030450 D1 DE 60030450D1
- Authority
- DE
- Germany
- Prior art keywords
- muc
- polypeptides
- peptides
- derived peptides
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 9
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 9
- 102100034256 Mucin-1 Human genes 0.000 title abstract 3
- 108010008707 Mucin-1 Proteins 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9921242.5A GB9921242D0 (en) | 1999-09-08 | 1999-09-08 | Cancer vaccine and diagnosis |
GB9921242 | 1999-09-08 | ||
EP99402237 | 1999-09-10 | ||
EP99402237 | 1999-09-10 | ||
US18721500P | 2000-03-03 | 2000-03-03 | |
US187215P | 2000-03-03 | ||
PCT/EP2000/008761 WO2001018035A2 (en) | 1999-09-08 | 2000-09-07 | Muc-1 derived peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60030450D1 true DE60030450D1 (de) | 2006-10-12 |
DE60030450T2 DE60030450T2 (de) | 2007-08-30 |
Family
ID=27240232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60030450T Expired - Lifetime DE60030450T2 (de) | 1999-09-08 | 2000-09-07 | Von MUC-1 abgeleitete Peptide |
Country Status (11)
Country | Link |
---|---|
US (3) | US20050142640A1 (de) |
EP (1) | EP1210430B1 (de) |
JP (1) | JP2003510094A (de) |
AT (1) | ATE338121T1 (de) |
AU (1) | AU778701B2 (de) |
CA (1) | CA2383737C (de) |
DE (1) | DE60030450T2 (de) |
DK (1) | DK1210430T3 (de) |
ES (1) | ES2270870T3 (de) |
PT (1) | PT1210430E (de) |
WO (1) | WO2001018035A2 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090004212A1 (en) * | 1997-12-30 | 2009-01-01 | Franz-Georg Hanisch | Tumour vaccines for MUC1-positive carcinomas |
EP1257565A4 (de) * | 2000-02-01 | 2005-04-06 | Austin Research Inst | Von mucin-1 abgeleitete antigene und ihre verwendung in der immuntherapie |
EP1958642A1 (de) | 2000-12-22 | 2008-08-20 | Dana-Farber Cancer Institute | Regulierung des Zellwachstums durch MUC1 |
ES2424131T3 (es) | 2001-03-27 | 2013-09-27 | Oncothyreon Inc. | Vacuna para modular respuestas inmunitarias entre T1 y T2 |
DE60238864D1 (de) | 2001-11-07 | 2011-02-17 | Mankind Corp | Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption |
JP2006504630A (ja) * | 2002-04-22 | 2006-02-09 | ダイアックス コーポレイション | ムチンポリペプチドに特異的な抗体 |
GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
GB0212046D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
GB0304634D0 (en) * | 2003-02-28 | 2003-04-02 | Glaxo Group Ltd | Vaccines |
US7696306B2 (en) | 2003-07-11 | 2010-04-13 | Board of Agents of the University of Nebraska | Compositions and methods for preventing or treating cancer |
GB0321614D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Vaccines |
WO2005042573A1 (en) | 2003-10-24 | 2005-05-12 | Dana-Farber Cancer Institute, Inc. | Modulation of the interaction of muc1 with muc1 ligands |
CA2547635C (en) * | 2003-12-12 | 2016-02-09 | Jeffrey Schlom | A human cytotoxic t-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of muc-1 |
TW201204410A (en) | 2004-04-01 | 2012-02-01 | Oncothyreon Inc | Mucinous glycoprotein (MUC-1) vaccine |
TWI511738B (zh) * | 2005-06-28 | 2015-12-11 | Oncothyreon Inc | 以黏液性糖蛋白(muc-1)疫苗治療病人之方法 |
WO2008011672A1 (en) * | 2006-07-25 | 2008-01-31 | 4G Vaccines Pty Ltd | A cancer vaccine comprising a mucin 1 (muc1) t cell epitope-derived peptide |
WO2008035350A1 (en) * | 2006-09-21 | 2008-03-27 | Vaxil Biotherapeutics Ltd. | Antigen specific multi epitope vaccines |
US7972870B2 (en) | 2007-02-02 | 2011-07-05 | Dana-Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3 |
US7871784B2 (en) | 2007-02-02 | 2011-01-18 | Dana-Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins |
US9156906B2 (en) | 2008-02-26 | 2015-10-13 | The Regents Of The University Of California | Glycopeptides and methods of making and using them |
CN102245632B (zh) | 2008-10-17 | 2018-10-12 | 达娜-法勃肿瘤研究所公司 | Muc-1胞质结构域肽作为癌症的抑制剂 |
WO2010138740A1 (en) | 2009-05-27 | 2010-12-02 | Dana-Farber Cancer Institute, Inc. | Inhibition 0f inflammation using antagonists of muc1 |
US8685928B2 (en) | 2010-02-12 | 2014-04-01 | Dana-Farber Cancer Institute, Inc. | Antagonists of MUC1 |
EP2374470A1 (de) * | 2010-04-08 | 2011-10-12 | Beta Innov | Therapeutische Anwendung von Protein Beta-2-M |
CA2798856C (en) | 2010-05-10 | 2019-04-23 | Ascend Biopharmaceuticals Pty Ltd | Immunostimulatory and vaccine compositions |
WO2012116225A2 (en) | 2011-02-24 | 2012-08-30 | Oncothyreon Inc. | Muc1 based glycolipopeptide vaccine with adjuvant |
RU2642300C2 (ru) | 2011-08-17 | 2018-01-24 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения |
WO2013103658A1 (en) * | 2012-01-03 | 2013-07-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Native and agonist ctl epitopes of the muc1 tumor antigen |
US9044421B2 (en) | 2012-03-28 | 2015-06-02 | Genus Oncology, Llc | Treating MUC1-expressing cancers with combination therapies |
EP3269726A4 (de) * | 2015-03-09 | 2018-12-05 | Nec Corporation | Peptid aus muc1, pharmazeutische zusammensetzung zur behandlung oder vorbeugung von krebs damit, immunitätsinduzierer und verfahren zur herstellung von antigen-präsentierenden zellen |
EP3903811A1 (de) * | 2020-05-01 | 2021-11-03 | R.G.C.C. Holdings AG | Pharmazeutische zusammensetzung und verfahren zur induzierung einer immunantwort |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
JPH02273195A (ja) * | 1988-11-17 | 1990-11-07 | Univ Melbourne | ヒト多型性上皮ムチンと反応するモノクローナル抗体 |
FR2668064B1 (fr) * | 1990-10-23 | 1994-12-16 | Transgene Sa | Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne. |
WO1993024525A1 (en) * | 1992-05-26 | 1993-12-09 | Rijksuniversiteit Leiden | PEPTIDES OF HUMAN p53 PROTEIN FOR USE IN HUMAN T CELL RESPONSE INDUCING COMPOSITIONS, AND HUMAN p53 PROTEIN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES |
IL110464A0 (en) | 1994-07-26 | 1994-10-21 | Univ Ramot | Novel proteins for the diagnosis, imaging, and therapy of human cancer |
US6548643B1 (en) * | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
US6024965A (en) | 1996-10-18 | 2000-02-15 | Erasums University Rotterdam | Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection |
DK1634949T3 (da) * | 1997-05-08 | 2011-03-28 | Oncothyreon Inc | Fremgangsmåde til at generere aktiverede T-celler og antigen-inkuberede antigen-præsenterende celler |
KR20010041656A (ko) * | 1998-03-05 | 2001-05-25 | 개리 이. 프라이드만 | 비-펩타이드 성선자극호르몬-방출 호르몬 제제 |
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
-
2000
- 2000-09-07 JP JP2001527622A patent/JP2003510094A/ja active Pending
- 2000-09-07 DK DK00965943T patent/DK1210430T3/da active
- 2000-09-07 WO PCT/EP2000/008761 patent/WO2001018035A2/en active IP Right Grant
- 2000-09-07 DE DE60030450T patent/DE60030450T2/de not_active Expired - Lifetime
- 2000-09-07 AT AT00965943T patent/ATE338121T1/de active
- 2000-09-07 CA CA2383737A patent/CA2383737C/en not_active Expired - Fee Related
- 2000-09-07 ES ES00965943T patent/ES2270870T3/es not_active Expired - Lifetime
- 2000-09-07 EP EP00965943A patent/EP1210430B1/de not_active Expired - Lifetime
- 2000-09-07 PT PT00965943T patent/PT1210430E/pt unknown
- 2000-09-07 AU AU76515/00A patent/AU778701B2/en not_active Ceased
-
2005
- 2005-02-11 US US11/055,119 patent/US20050142640A1/en not_active Abandoned
-
2008
- 2008-03-04 US US12/042,196 patent/US20080227082A1/en not_active Abandoned
-
2009
- 2009-10-13 US US12/578,499 patent/US7892828B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2001018035A3 (en) | 2001-11-08 |
AU7651500A (en) | 2001-04-10 |
AU778701B2 (en) | 2004-12-16 |
DE60030450T2 (de) | 2007-08-30 |
JP2003510094A (ja) | 2003-03-18 |
PT1210430E (pt) | 2006-12-29 |
EP1210430B1 (de) | 2006-08-30 |
DK1210430T3 (da) | 2006-11-20 |
US20080227082A1 (en) | 2008-09-18 |
WO2001018035A2 (en) | 2001-03-15 |
CA2383737A1 (en) | 2001-03-15 |
WO2001018035A9 (en) | 2002-09-06 |
ES2270870T3 (es) | 2007-04-16 |
ATE338121T1 (de) | 2006-09-15 |
US20100255501A1 (en) | 2010-10-07 |
EP1210430A2 (de) | 2002-06-05 |
CA2383737C (en) | 2011-01-18 |
US20050142640A1 (en) | 2005-06-30 |
US7892828B2 (en) | 2011-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |