DE60026452D1 - Verfahren zur Identifizierung von Peptidensequenzen und Proteinensequenzen mittels Massenspektromterie - Google Patents

Verfahren zur Identifizierung von Peptidensequenzen und Proteinensequenzen mittels Massenspektromterie

Info

Publication number
DE60026452D1
DE60026452D1 DE60026452T DE60026452T DE60026452D1 DE 60026452 D1 DE60026452 D1 DE 60026452D1 DE 60026452 T DE60026452 T DE 60026452T DE 60026452 T DE60026452 T DE 60026452T DE 60026452 D1 DE60026452 D1 DE 60026452D1
Authority
DE
Germany
Prior art keywords
sequences
identification
mass spectrometry
peptide sequences
protein sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60026452T
Other languages
English (en)
Other versions
DE60026452T2 (de
Inventor
John Skilling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9907810.7A external-priority patent/GB9907810D0/en
Priority claimed from GBGB9908684.5A external-priority patent/GB9908684D0/en
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Application granted granted Critical
Publication of DE60026452D1 publication Critical patent/DE60026452D1/de
Publication of DE60026452T2 publication Critical patent/DE60026452T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60026452T 1999-04-06 2000-04-06 Verfahren zur Identifizierung von Peptidensequenzen und Proteinensequenzen mittels Massenspektromterie Expired - Lifetime DE60026452T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9907810.7A GB9907810D0 (en) 1999-04-06 1999-04-06 A method of determining peptide sequences by mass spectrometry
GB9907810 1999-04-06
GBGB9908684.5A GB9908684D0 (en) 1999-04-16 1999-04-16 Improved methods of identifying peptides and proteins by mass spectrometry
GB9908684 1999-04-16
EP00302897A EP1047107B1 (de) 1999-04-06 2000-04-06 Verfahren zur Identifizierung von Peptiden und Proteinen mittels Massenspektromterie

Publications (2)

Publication Number Publication Date
DE60026452D1 true DE60026452D1 (de) 2006-05-04
DE60026452T2 DE60026452T2 (de) 2006-08-10

Family

ID=57132898

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60026452T Expired - Lifetime DE60026452T2 (de) 1999-04-06 2000-04-06 Verfahren zur Identifizierung von Peptidensequenzen und Proteinensequenzen mittels Massenspektromterie

Country Status (4)

Country Link
US (1) US6489608B1 (de)
EP (2) EP1688987A1 (de)
CA (1) CA2303761C (de)
DE (1) DE60026452T2 (de)

Cited By (1)

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CN111830113A (zh) * 2019-04-15 2020-10-27 布鲁克道尔顿有限公司 确定蛋白质和肽的异构氨基酸残基的方法

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WO2001069219A2 (en) * 2000-03-14 2001-09-20 National Research Council Canada Faims apparatus and method with laser-based ionization source
US7091479B2 (en) * 2000-05-30 2006-08-15 The Johns Hopkins University Threat identification in time of flight mass spectrometry using maximum likelihood
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
GB0014342D0 (en) * 2000-06-13 2000-08-02 Scient Analysis Instr Limited Method of analysis
SE517259C2 (sv) * 2000-06-14 2002-05-14 Jan Eriksson System för molekylidentifiering
AUPR116100A0 (en) 2000-11-01 2000-11-23 University Of Sydney, The P450 gene regulation
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
WO2003056299A2 (en) * 2001-11-05 2003-07-10 Irm Llc Labeling reagent and methods of use
DE10155707B4 (de) 2001-11-13 2006-11-16 Bruker Daltonik Gmbh Massenbestimmung für Biopolymere
US20030153007A1 (en) * 2001-12-28 2003-08-14 Jian Chen Automated systems and methods for analysis of protein post-translational modification
CA2476412C (en) 2002-03-22 2008-02-19 Phenomenome Discoveries Inc. Method of visualizing non-targeted metabolomic data generated from fourier transform ion cyclotron resonance mass spectrometers
US8715309B2 (en) 2002-04-29 2014-05-06 Steven Schraga Lancet device
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US7409296B2 (en) * 2002-07-29 2008-08-05 Geneva Bioinformatics (Genebio), S.A. System and method for scoring peptide matches
JP4686450B2 (ja) * 2003-04-28 2011-05-25 セルノ・バイオサイエンス・エルエルシー 質量スペクトル分析の計算方法およびシステム
US20070158542A1 (en) * 2003-05-15 2007-07-12 Electrophoretics Limited Mass spectrometry
US7072772B2 (en) * 2003-06-12 2006-07-04 Predicant Bioscience, Inc. Method and apparatus for modeling mass spectrometer lineshapes
US20050255606A1 (en) * 2004-05-13 2005-11-17 Biospect, Inc., A California Corporation Methods for accurate component intensity extraction from separations-mass spectrometry data
EP1644860A4 (de) * 2003-06-27 2008-08-06 Locus Pharmaceuticals Inc Verfahren und computerprogrammprodukt zum entdecken von drogen durch verwendung gewichteter grosser kanonischer metropolis-monte-carlo-stichproben
US20040267456A1 (en) * 2003-06-27 2004-12-30 Stephan Brunner Method and computer program product for drug discovery using weighted grand canonical metropolis Monte Carlo sampling
WO2005031343A1 (en) * 2003-10-01 2005-04-07 Proteome Systems Intellectual Property Pty Ltd A method for determining the biological likelihood of candidate compositions or structures
WO2005057208A1 (en) * 2003-12-03 2005-06-23 Prolexys Pharmaceuticals, Inc. Methods of identifying peptides and proteins
US7415361B2 (en) * 2003-12-09 2008-08-19 Locus Pharmaceuticals, Inc. Methods and systems for analyzing and determining ligand-residue interaction
DE102004012524B4 (de) * 2004-03-15 2006-11-16 Mosaiques Diagnostics And Therapeutics Ag Verfahren zur Bestimmung wahrer Molekülmassen von Konstituenten biologischer Proben
US20050222776A1 (en) * 2004-03-31 2005-10-06 Locus Pharmaceuticals, Inc. Method for fragment preparation
GB0409676D0 (en) * 2004-04-30 2004-06-02 Micromass Ltd Mass spectrometer
GB2413695B (en) * 2004-04-30 2009-01-21 Micromass Ltd Mass spectrometer
EP1931995A4 (de) 2005-09-12 2010-08-04 Phenomenome Discoveries Inc Verfahren zur diagnose von gesundheitszuständen bei kolorektal- und ovarialkarzinom
GB2432712B (en) 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
US7429727B2 (en) * 2005-12-13 2008-09-30 Palo Alto Research Center Incorporated Method, apparatus, and program product for quickly selecting complex molecules from a data base of molecules
US8108153B2 (en) * 2005-12-13 2012-01-31 Palo Alto Research Center Incorporated Method, apparatus, and program product for creating an index into a database of complex molecules
GB0609253D0 (en) 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer
WO2008074067A1 (en) * 2006-12-18 2008-06-26 Macquarie University Detection and quantification of polypeptides using mass spectrometry
US7755744B1 (en) * 2007-08-15 2010-07-13 Thomas Leberer Environment sensor that conveys information about objects in the vicinity of the visually impaired user
CN101886928A (zh) * 2009-05-14 2010-11-17 深圳富泰宏精密工业有限公司 具有导盲功能的便携式电子装置
GB201100302D0 (en) * 2011-01-10 2011-02-23 Micromass Ltd A method of correction of data impaired by hardware limitions in mass spectrometry
GB201100300D0 (en) * 2011-01-10 2011-02-23 Micromass Ltd A method of deadtime correction in mass spectrometry
AU2014214709B2 (en) 2013-02-08 2018-05-31 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Biomolecular processing platform and uses thereof
DK3548652T3 (da) 2016-12-01 2024-07-08 Nautilus Subsidiary Inc Fremgangsmåder til proteinanalyse
CA3079832A1 (en) * 2017-10-23 2019-05-02 Nautilus Biotechnology, Inc. Methods and systems for protein identification
US11721412B2 (en) 2017-10-23 2023-08-08 Nautilus Subsidiary, Inc. Methods for identifying a protein in a sample of unknown proteins
JP7458678B2 (ja) 2017-12-29 2024-04-01 ノーティラス・サブシディアリー・インコーポレイテッド タンパク質同定のためのデコーディングアプローチ方法
CN108491690B (zh) * 2018-03-16 2020-06-05 中国科学院数学与***科学研究院 一种蛋白质组学中肽段的肽段定量效率预测方法
EP3598135A1 (de) * 2018-07-20 2020-01-22 Univerzita Palackého v Olomouci Verfahren zur identifizierung von entitäten aus massenspektren

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US5331158A (en) * 1992-12-07 1994-07-19 Hewlett-Packard Company Method and arrangement for time of flight spectrometry
US6017693A (en) 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
GB2308917B (en) * 1996-01-05 2000-04-12 Maxent Solutions Ltd Reducing interferences in elemental mass spectrometers
GB9616105D0 (en) * 1996-07-31 1996-09-11 Univ Kingston TrkA binding site of NGF
GB9710582D0 (en) 1997-05-22 1997-07-16 Oxford Glycosciences Uk Ltd A method for de novo peptide sequence determination

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111830113A (zh) * 2019-04-15 2020-10-27 布鲁克道尔顿有限公司 确定蛋白质和肽的异构氨基酸残基的方法
CN111830113B (zh) * 2019-04-15 2023-09-22 布鲁克·道尔顿有限及两合公司 确定蛋白质和肽的异构氨基酸残基的方法

Also Published As

Publication number Publication date
EP1047107A3 (de) 2002-12-18
DE60026452T2 (de) 2006-08-10
EP1047107A2 (de) 2000-10-25
CA2303761A1 (en) 2000-10-06
US6489608B1 (en) 2002-12-03
CA2303761C (en) 2005-12-20
EP1047107B1 (de) 2006-10-04
EP1688987A1 (de) 2006-08-09

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