DE60019098D1 - Verfahren zur reinigung von polyhydroxyalkanoaten - Google Patents

Verfahren zur reinigung von polyhydroxyalkanoaten

Info

Publication number
DE60019098D1
DE60019098D1 DE60019098T DE60019098T DE60019098D1 DE 60019098 D1 DE60019098 D1 DE 60019098D1 DE 60019098 T DE60019098 T DE 60019098T DE 60019098 T DE60019098 T DE 60019098T DE 60019098 D1 DE60019098 D1 DE 60019098D1
Authority
DE
Germany
Prior art keywords
biomass
pha
slurry
solvent
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60019098T
Other languages
English (en)
Other versions
DE60019098T2 (de
Inventor
Daniel Horowitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yield10 Bioscience Inc
Original Assignee
Metabolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolix Inc filed Critical Metabolix Inc
Publication of DE60019098D1 publication Critical patent/DE60019098D1/de
Application granted granted Critical
Publication of DE60019098T2 publication Critical patent/DE60019098T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/90Purification; Drying
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/89Recovery of the polymer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • C12P7/625Polyesters of hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE60019098T 1999-05-12 2000-05-12 Verfahren zur reinigung von polyhydroxyalkanoaten Expired - Lifetime DE60019098T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13374799P 1999-05-12 1999-05-12
US133747P 1999-05-12
PCT/US2000/013039 WO2000068409A1 (en) 1999-05-12 2000-05-12 Methods for purifying polyhydroxyalkanoates

Publications (2)

Publication Number Publication Date
DE60019098D1 true DE60019098D1 (de) 2005-05-04
DE60019098T2 DE60019098T2 (de) 2006-02-02

Family

ID=22460122

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60019098T Expired - Lifetime DE60019098T2 (de) 1999-05-12 2000-05-12 Verfahren zur reinigung von polyhydroxyalkanoaten

Country Status (9)

Country Link
US (2) US6340580B1 (de)
EP (1) EP1175499B1 (de)
JP (1) JP4790912B2 (de)
AT (1) ATE292188T1 (de)
AU (1) AU750835B2 (de)
CA (1) CA2373131C (de)
DE (1) DE60019098T2 (de)
ES (1) ES2239004T3 (de)
WO (1) WO2000068409A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10013514C2 (de) * 2000-03-14 2002-06-27 Ufz Leipzighalle Gmbh Verfahren zur Gewinnung von Polyhydroxyalkanoaten (PHA) oder deren Copolymeren
GB2373743B (en) * 2001-03-27 2004-11-03 Membrane Extraction Tech Ltd Solvent exchange process
BR0313251A (pt) * 2002-08-06 2005-07-05 Metabolix Inc Métodos de extração de polìmero
DE10247157A1 (de) * 2002-10-09 2004-04-22 Messo-Chemietechnik Gmbh Formgebung und Wäsche gelbildender Biopolymere
US8283435B2 (en) * 2003-02-21 2012-10-09 Metabolix, Inc. PHA adhesive compositions
JP5079321B2 (ja) * 2003-02-21 2012-11-21 メタボリックス インコーポレイティッド Pha接着組成物
TW200613560A (en) * 2004-06-29 2006-05-01 Procter & Gamble Solvent extraction of polyhydroxyalkanoates from biomass
TW200617171A (en) * 2004-06-29 2006-06-01 Procter & Gamble Improved process for the solvent-based extraction of polyhydroxyalkanoates from biomass
JP4945447B2 (ja) * 2004-09-13 2012-06-06 メタボリックス インコーポレイティッド 単一溶媒ポリマーの抽出方法
US7118897B2 (en) * 2004-09-15 2006-10-10 The Procter & Gamble Company Process for the extraction of polyhydroxyalkanoates from biomass
US20060057691A1 (en) * 2004-09-15 2006-03-16 Karunakaran Narasimhan Process for the extraction of polyhydroxyalkanoates from biomass
JPWO2008026619A1 (ja) * 2006-08-30 2010-01-21 株式会社カネカ 3−ヒドロキシアルカン酸共重合体の製造方法
US7514525B2 (en) * 2007-03-09 2009-04-07 University Of Hawaii Recovery and purification of polyhydroxyalkanoates
EP2663287A1 (de) 2011-01-12 2013-11-20 Intervet International B.V. Verwendung eines flüssigmedienaustauschs durch querstromfilterung bei der herstellung von wirkstoffsuspensionen
ES2448823B1 (es) 2012-08-14 2014-10-13 Neol Biosolutions, S.A. Producción de bioplásticos
CN109054254B (zh) 2012-08-17 2021-02-02 Cj第一制糖株式会社 用于聚合物共混物的生物基橡胶改性剂
US10669417B2 (en) 2013-05-30 2020-06-02 Cj Cheiljedang Corporation Recyclate blends
EP3122817B1 (de) 2014-03-27 2020-07-29 CJ CheilJedang Corporation Hoch gefüllte polymersysteme
CN109173422B (zh) * 2018-10-09 2021-03-09 飞潮(无锡)过滤技术有限公司 一种医药生产中转晶前工序api药液的批次完全过滤工艺

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336334A (en) * 1979-02-21 1982-06-22 Imperial Chemical Industries Limited Microbiological process for the production of poly(β-hydroxybutyric acid)
EP0015123B1 (de) * 1979-02-21 1982-12-22 Imperial Chemical Industries Plc Verfahren zur Extraktion von Poly-(3-Hydroxybuttersäure) aus mikrobiellen Zellen
FR2567149B1 (fr) * 1984-07-06 1986-12-05 Solvay Procede pour l'extraction de poly-beta-hydroxybutyrates au moyen d'un solvant a partir d'une suspension aqueuse de micro-organismes
GB8927794D0 (en) * 1989-12-08 1990-02-14 Ici Plc Copolymer production
US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
US5281691A (en) * 1992-06-19 1994-01-25 Eastman Kodak Company Poly(3-hydroxyalkanoates)
KR100262358B1 (ko) * 1995-08-21 2000-08-01 데이비드 엠 모이어 피에이치에이에대한한계적비용매를사용하여촉진되는바이오매스로부터폴리하이드록시알카노에이트의용매추출방법
US5942597A (en) * 1995-08-21 1999-08-24 The Procter & Gamble Company Solvent extraction of polyhydroxyalkanoates from biomass
US6083729A (en) * 1995-10-26 2000-07-04 Metabolix, Inc. Methods for isolating polyhydroxyalkanoates from plants
US5821299A (en) * 1996-02-16 1998-10-13 The Proctor & Gamble Company Solvent extraction of polyhydroxy-alkanoates from biomass facilitated by the use of marginal nonsolvent
DE69837914T2 (de) * 1997-04-15 2008-02-21 Metabolix, Inc., Cambridge Hochtemperatur-PHA Extraktion mit schlecht-lösenden Lösungsmittel für PHA
US6043063A (en) * 1997-04-15 2000-03-28 Monsanto Company Methods of PHA extraction and recovery using non-halogenated solvents
US6156852A (en) * 1997-04-21 2000-12-05 Monsanto Company Hydroxy-terminated polyhydroxyalkanoates

Also Published As

Publication number Publication date
AU750835B2 (en) 2002-08-01
ATE292188T1 (de) 2005-04-15
AU4844000A (en) 2000-11-21
JP4790912B2 (ja) 2011-10-12
EP1175499A1 (de) 2002-01-30
US6340580B1 (en) 2002-01-22
WO2000068409A1 (en) 2000-11-16
CA2373131C (en) 2004-11-02
EP1175499B1 (de) 2005-03-30
JP2002543794A (ja) 2002-12-24
CA2373131A1 (en) 2000-11-16
ES2239004T3 (es) 2005-09-16
US20020058316A1 (en) 2002-05-16
DE60019098T2 (de) 2006-02-02

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